Sophie Vantyghem, Pierre Peterlin, Sylvain Thepot, Audrey Menard, Viviane Dubruille, Camille De-bord, Thierry Guillaume, Alice Garnier, Amandine Le Bourgeois, Soraya Wuilleme, Catherine Godon, Olivier Theisen, Marion Eveillard, Jacques Delaunay, Herv Maisonneuve, Nadine Morineau, Bruno Villemagne, Stephane Vigouroux, Francois Subiger, Elsa Lestang, Marion Loirat, Anne Parcelier, Pascal Godmer, Melanie Mercier, Adrien Trebouet, Damien Luque Paz, Ronan Le Calloch, Lena g Le Clech, Celine Bossard, Anne Moreau, Valerie Ugo, Mathilde Hunault, Philippe Moreau, Steven Le Gouill, Patrice Chevallier, Marie C Bene, and Yannick Le Bris. Diagnosis and prognosis are comforted by integrated assessment of next-generation sequencing in chronic myeloid malignancies. A real-life study. Haematologica, 2020. inserm-02552097.
Marion Eveillard, Even Rustad, Mikhail Roshal, Yanming Zhang, Amanda Ciardiello, Neha Korde, Malin Hultcrantz, Sydney Lu, Urvi Shah, Hani Hassoun, Eric Smith, Alexander Lesokhin, Sham Mailankody, Ola Landgren, and Katie Thoren. Comparison of MALDI-TOF mass spectrometry analysis of peripheral blood and bone marrow-based ow cytometry for tracking measurable residual disease in patients with multiple myeloma. British Journal of Haematology, 2020. inserm-02534427.
Gregory Lazarian, Chloe Friedrich, Anne Quinquenel, Julie Tran, Souhail Ouriemmi, Elisabetta Dondi, Antoine Martin, Imane Mihoub, David Chiron, Celine Bellanger, Carole Fleury, Pascal Gelebart, Emmet McCormack, Dominique Ledoux, Catherine Thieblemont, Jacek Marzec, John Gribben, Florence Cymbalista, Nadine Varin-Blank, Laura Gardano, and Fanny Baran-Marszak. Stabilization of -catenin upon B-cell receptor signaling promotes NF-kB target genes transcription in mantle cell lymphoma. Oncogene, 2020. inserm-02534412.
Baptiste Le Calvez, Yannick Le Bris, Guillaume Herbreteau, Bastien Jamet, Celine Bossard, Benoit Tessoulin, Thomas Gastinne, Beatrice Mahe, Viviane Dubruille, Nicolas Blin, Chloe Antier, Olivier Theisen, Francoise Kraeber-Bodere, Steven Le Gouill, Marie C. Bene, Philippe Moreau, and Cyrille Touzeau. RASmutation leading to acquired resistance to dabrafenib and trametinib therapy in a multiplemyeloma patient harboring BRAF mutation. European Journal of Haematology, 2020. inserm-02874002.
Clement Bailly, Thomas M Carlier, Francoise Kraeber-Bodere, Steven L Le Gouill, and Caroline Bodet-Milin. Reply to E. La on et al. Haematologica, 2020. inserm-02908548.
Maxime Jullien, Patricia Gomez-Bougie, David Chiron, and Cyrille Touzeau. Restoring Apoptosis with BH3 Mimetics in Mature B-Cell Malignancies. Cells, 2020. inserm-02512852.
Steven Le Gouill, Franck Morschhauser, David Chiron, Krimo Bouabdallah, Guillaume Cartron, Olivier Casasnovas, Caroline M Bodet-Milin, Sylviane Ragot, Celine Bossard, Nathalie Nadal, Charles Herbaux, Benoit Tessoulin, Emmanuelle Tchernonog, Cedric Rossi, Rory Mc Culloch, Thomas Gastinne, Mary Callanan, and Simon Rule. Ibrutinib, Obinutuzumab And Venetoclax In Relapsed and Untreated Patients with Mantle-Cell Lymphoma, a phase I/II trial. Blood, 2020. inserm-03063717.
Carolane Seiller, Sophie Maiga, Cyrille Touzeau, Celine Bellanger, Charlotte Kervoelen, Geraldine Descamps, Laurent Maillet, Philippe Moreau, Catherine Pellat-Deceunynck, Patricia Gomez-Bougie, and Martine Amiot. Dual targeting of BCL2 and MCL1 rescues myeloma cells resistant to BCL2 and MCL1 inhibitors associated with the formation of BAX/ BAK hetero-complexes. Cell Death and Disease, 2020. inserm-02563554.
Yannick Le Bris, Florence Magrangeas, Anne Moreau, David Chiron, Catherine Guerin-Charbonnel, Olivier Theisen, Olivier Pichon, Danielle Canioni, Barbara Burroni, Hervé Maisonneuve, Catherine Thieblemont, Lucie Oberic, Emmanuel Gyan, Catherine Pellat-Deceunynck, Olivier Hermine, Marie-Helene Delfau-Larue, Benoit Tessoulin, Marie C Bene, Stephane Minvielle, and Steven Le Gouill. Whole genome copy number analysis in search of new prognostic biomarkers in rst line treatment of mantle cell lymphoma. A study by the LYSA group. Hematological Oncology, 2020. inserm-02874026.
Steven Lohard, Nathalie Bourgeois, Laurent A Maillet, Fabien P Gautier, Aurelie Fetiveau, Hamza Lasla, Frederique Nguyen, Celine Vuillier, Alison Dumont, Agnes Moreau-Aubry, Morgane Frapin, Laurent David, Delphine Loussouarn, Olivier Kerdraon, Mario Campone, Pascal Jezequel, Philippe Juin, and Sophie Barille-Nion. STING-dependent paracriny shapes apoptotic priming of breast tumors in response to anti-mitotic treatment. Nature Communications, 2020. inserm-02448103.
Clement Bailly, Thomas Carlier, Alina Berriolo-Riedinger, Olivier Casasnovas, Emmanuel Gyan, Michel Meignan, Anne Moreau, Barbara Burroni, Lo c Djaileb, Remy Gressin, Anne Devillers, Thierry Lamy, Catherine Thieblemont, Olivier Hermine, Francoise Kraeber-Bodere, Steven Le Gouill, and Caroline M Bodet-Milin. Prognostic value of FDG-PET in patients with mantle cell lym-phoma: results from the LyMa-PET Project. Haematologica, 2020. inserm-02266351.
Benoit Tessoulin, Kamal Bouabdallah, Barbara Burroni, Thierry Lamy, Remy Gressin, Guillaume Cartron, Catherine Thieblemont, Clementine Sarkozy, Corinne Haioun, Olivier Casasnovas, Clemen-tine Joubert, Emmanuel Gyan, Olivier Hermine, and Steven Le Gouill. Safety and e cacy of tem-sirolimus in combination with three di erent immuno-chemotherapy regimens in relapse and refrac-tory mantle cell lymphoma, nal results of the T phase IB trial of the LYSA. Annals of Hematology, 2020. hal-02890227.
Sophie Allain-Maillet, Adrien Bosseboeuf, Nicolas Mennesson, Megane Bostoen, Laura Dufeu, Eun Ho Choi, Cedric Cleyrat, Olivier Mansier, Eric Lippert, Yannick Le Bris, Jean-Marc Gombert, Francois Girodon, Magali Pettazzoni, Edith Bigot-Corbel, and Sylvie Hermouet. Anti-Glucosylsphingosine Autoimmunity, JAK2V617F-Dependent Interleukin-1 and JAK2V617F-Independent Cytokines in Myeloproliferative Neoplasms. Cancers, 2020. inserm-02945854.
Bastien Jamet, Clément Bailly, Thomas Carlier, Cyrille Touzeau, Cristina Nanni, Elena Zamagni, Louisa Barré, Anne-Victoire Michaud, Michel Chérel, Philippe Moreau, Caroline Bodet-Milin, Françoise Kraeber-Bodéré. Interest of PET Imaging in Multiple Myeloma. Frontiers in Medicine. (2019) 69. hal-02088227
Benoit Tessoulin, Antonin Papin, Patricia Gomez-Bougie, Céline Bellanger, Martine Amiot, Catherine Pellat-Deceunynck, David Chiron. BCL2-Family Dysregulation in B-Cell Malignancies: From Gene Expression Regulation to a Targeted Therapy Biomarker. Frontiers in Oncology. (2019) 645. hal-02128662
Bastien Jamet, Clément Bailly, Thomas Carlier, Lucie Planche, Cyrille Touzeau, Françoise Kraeber-Bodéré, Philippe Moreau, Caroline Bodet-Milin. Added prognostic value of FDG-PET/CT in relapsing multiple myeloma patients. Leukemia & lymphoma. (2019) 222-225. inserm-01823037
Louise Bouard, Caroline Bodet-Milin, Clément Bailly, Thierry Guillaume, Pierre Peterlin, Alice Garnier, Amandine Bourgeois, Béatrice Mahé, Viviane Dubruille, Nicolas Blin, Cyrille Touzeau, Thomas Gastinne, Anne Lok, Antoine Bonnet, Marie Bene, Steven Gouill, Philippe Moreau, Françoise Kraeber-Bodéré, Patrice Chevallier. Deauville Scores 4 or 5 Assessed by Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Early Post-Allotransplant Is Highly Predictive of Relapse in Lymphoma Patients. Biology of Blood and Marrow Transplantation. (2019) 906-911. inserm-01981440
Benoit Tessoulin, Antonin Papin, Patricia Gomez-Bougie, Céline Bellanger, Martine Amiot, Catherine Pellat-Deceunynck, David Chiron. BCL2-Family Dysregulation in B-Cell Malignancies: From Gene Expression Regulation to a Targeted Therapy Biomarker. Frontiers in Oncology. (2019) 645. inserm-01990870
Kevin Louault, Thomas Bonneaud, Céline Séveno, Patricia Gomez-Bougie, Frédérique Nguyen, Fabien Gautier, Nathalie Bourgeois, Delphine Loussouarn, Olivier Kerdraon, Sophie Barillé-Nion, Pascal Jézéquel, Mario Campone, Martine Amiot, Philippe Juin, Frédérique Souazé. Interactions between cancer-associated fibroblasts and tumor cells promote MCL-1 dependency in estrogen receptor-positive breast cancers. Oncogene. (2019) Epub ahead of print. inserm-01991165
Pierre Peterlin, Joëlle Gaschet, Thierry Guillaume, Alice Garnier, Marion Eveillard, Amandine Le Bourgeois, Michel Chérel, Camille Debord, Yannick Le Bris, Olivier Theisen, Béatrice Mahé, Viviane Dubruille, Catherine Godon, Nelly Robillard, Soraya Wuilleme, Cyrille Touzeau, Thomas Gastinne, Nicolas Blin, Anne Lok, Antoine Bonnet, Steven Le Gouill, Philippe Moreau, Marie-Christine Béné, Patrice Chevallier. FLT3 ligand plasma levels in acute myeloid leukemia. Haematologica. (2019) Epub ahead of print. inserm-01993986
Agathe Dubuisson, Cécile Favreau, Eric Fourmaux, Sabrina Lareure, Rafael Rodrigues-Saraiva, Catherine Pellat-Deceunynck, Said El Alaoui, Olivier Micheau. Generation and characterization of novel anti-DR4 and anti-DR5 antibodies developed by genetic immunization. Cell Death and Disease. (2019) Epub ahead of print. inserm-02006230
Benoit Tessoulin, Géraldine Descamps, Christelle Dousset, Martine Amiot, Catherine Pellat-Deceunynck. Targeting Oxidative Stress With Auranofin or Prima-1Met to Circumvent p53 or Bax/Bak Deficiency in Myeloma Cells. Frontiers in Oncology. (2019). inserm-02055153
David Chiron. Three targets in 1 shot against ibrutinib resistance. Blood. (2019). inserm-02080892
Antonin Papin, Benoit Tessoulin, Céline Bellanger, Anne Moreau, Yannick Le Bris, Hervé Maisonneuve, Philippe Moreau, Cyrille Touzeau, Martine Amiot, Catherine Pellat-Deceunynck, Steven Le Gouill, David Chiron. CSF1R and BTK inhibitions as novel strategies to disrupt the dialogue between mantle cell lymphoma and macrophages. Leukemia. (2019) Epub ahead of print. inserm-02081007
Clément Bailly, Thomas Carlier, Cyrille Touzeau, Nicolas Arlicot, Françoise Kraeber-Bodéré, Steven Le Gouill, Caroline Bodet-Milin. Interest of FDG-PET in the Management of Mantle Cell Lymphoma. Frontiers in Medicine. (2019) Epub ahead of print. inserm-02100231
Clément Bailly, Thomas Carlier, Bastien Jamet, Cyrille Touzeau, Philippe Moreau, Françoise Kraeber-Bodéré, Caroline Bodet-Milin. 18F-FDG PET/CT in multiple myeloma: critical insights and future directions. European Journal of Nuclear Medicine and Molecular Imaging. (2019) 1048-1050. inserm-02100540
Ludivine Morvan, Diana Mateus, Clément Bailly, Bastien Jamet, Caroline Bodet-Milin, Philippe Moreau, Cyrille Touzeau, Françoise Kraeber-Bodéré, Thomas Carlier. Prédiction de la progression chez des patients atteints de myélome multiple par « Random Survival Forest ».[Poster]. (2019). inserm-02100680
Aimeric Dabin, Thomas Goronflot, Benoît Tessoulin, David Chiron, Anne Monlien, Steven Le Gouill, Pierre-Antoine Gourraud, Matilde Karakachoff. Bridging Refract-Lyma and CHUN Clinical Data Warehouse: from a research cohort to a regional electronic medical record system and back. [Poster] (2019). inserm-02163132
Jonathan Harnoss, Adrien Le Thomas, Anna Shemorry, Scot Marsters, David Lawrence, Min Lu, Yung-Chia Chen, Jing Qing, Klara Totpal, David Kan, Ehud Segal, Mark Merchant, Mike Reichelt, Heidi Wallweber, Weiru Wang, Kevin Clark, Susan Kaufman, Maureen Beresini, Steven Laing, Wendy Sandoval, Maria Lorenzo, Jiansheng Wu, Justin Ly, Tom De Bruyn, Amy Heidersbach, Benjamin Haley, Alvin Gogineni, Robby Weimer, Dong Lee, Marie-Gabrielle Braun, Joachim Rudolph, Michael VanWyngarden, Daniel Sherbenou, Patricia Gomez-Bougie, Martine Amiot, Diego Acosta-Alvear, Peter Walter, Avi Ashkenazi. Disruption of IRE1α through its kinase domain attenuates multiple myeloma. Proceedings of the National Academy of Sciences of the United States of America. (2019) 201906999. inserm-02265831
Clément Bailly, Thomas Carlier, Alina Berriolo-Riedinger, Olivier Casasnovas, Emmanuel Gyan, Michel Meignan, Anne Moreau, Barbara Burroni, Loïc Djaileb, Rémy Gressin, Anne Devillers, Thierry Lamy, Catherine Thieblemont, Olivier Hermine, Françoise Kraeber-Bodéré, Steven Le Gouill, Caroline Bodet-Milin. Prognostic value of FDG-PET in patients with mantle cell lymphoma: results from the LyMa-PET Project. Haematologica. (2019) Epub ahead of print. inserm-02266351
Pierre Peterlin, Joëlle Gaschet, Thierry Guillaume, Alice Garnier, Marion Eveillard, Amandine Le Bourgeois, Michel Chérel, Camille Debord, Yannick Le Bris, Olivier Theisen, Béatrice Mahé, Viviane Dubruille, Catherine Godon, Nelly Robillard, Soraya Wuilleme, Cyrille Touzeau, Thomas Gastinne, Nicolas Blin, Anne Lok, Antoine Bonnet, Steven Le Gouill, Philippe Moreau, Marie-C Béné, Patrice Chevallier. FLT3 ligand plasma levels have no impact on outcomes after allotransplant in acute leukemia. Cytokine. (2019) 85-87. inserm-02266372
Tiphaine Douanne, Gwennan André-Grégoire, Kilian Trillet, An Thys, Antonin Papin, Magalie Feyeux, Philippe Hulin, David Chiron, Julie Gavard, Nicolas Bidère. Pannexin‐1 limits the production of proinflammatory cytokines during necroptosis. EMBO Reports. (2019) e47840. inserm-02281304
Lina Benaniba, Benoit Tessoulin, Sabrina Trudel, Catherine Pellat-Deceunynck, Martine Amiot, Stephane Minvielle, Pierre Gourraud, Sophie de Visme, Hervé Maisonneuve, Anne Lok, Steven Le Gouill, Philippe Moreau, Cyrille Touzeau. The MYRACLE protocol study: a multicentric observational prospective cohort study of patients with multiple myeloma. BMC Cancer (2019) 19-1. inserm-02290127
Yassine Al Tabaa, Emmanuel Tchernonog, Pierre Faurie, Anne Ségolène Cottereau, Hélène Monjanel, Antoine Bonnet, Steven Le Gouill, Emmanuel Gyan, Hervé Ghesquières, Denis Mariano-Goulart, Guillaume Cartron. Post-treatment positron emission tomography-computed tomography is highly predictive of outcome in Plasmablastic lymphoma. European Journal of Nuclear Medicine and Molecular Imaging. (2018) 1705-1709. hal-01833550
Patrick Casara, James Davidson, Audrey Claperon, Gaëtane Le Toumelin-Braizat, Meike Vogler, Alain Bruno, Maïa Chanrion, Gaëlle Lysiak-Auvity, Thierry Le Diguarher, Jérôme-Benoît Starck, Ijen Chen, Neil Whitehead, Christopher Graham, Natalia Matassova, Pawel Dokurno, Christopher Pedder, Youzhen Wang, Shumei Qiu, Anne-Marie Girard, Emilie Schneider, Fabienne Gravé, Aurélie Studeny, Ghislaine Guasconi, Francesca Rocchetti, Sophie Maïga, Jean-Michel Henlin, Frédéric Colland, Laurence Kraus-Berthier, Steven Le Gouill, Martin Dyer, Roderick Hubbard, Mike Wood, Martine Amiot, Gerald Cohen, John Hickman, Erick Morris, James Murray, Olivier Geneste. S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth. Oncotarget. (2018) 20075 – 20088. inserm-01807731
Roch Houot, G Cartron, Fontanet Bijou, Sophie De Guibert, Gilles A. Salles, Christophe Fruchart, Krimo Bouabdallah, Marie Maerevoet, Pierre Feugier, Steven Le Gouill, Hervé Tilly, Rene-Olivier Casasnovas, Cécile Moluçon-Chabrot, Eric Van Den Neste, Pierre Zachee, Marc Andre, Christophe Bonnet, Corinne Haioun, Achiel Van Hoof, Koen Van Eygen, Lysiane Molina, Emmanuelle Nicolas-Virelizier, Philippe Ruminy, Franck Morschhauseur. Obinutuzumab plus Lenalidomide (GALEN) for the treatment of relapse/refractory aggressive lymphoma: a phase II LYSA study. Leukemia. (2018) 776-780. inserm-01934613
Alix Augustin, Steven Le Gouill, Remy Gressin, Aurélie Bertaut, Alain Monnereau, Anne Woronoff, Brigitte Tretarre, Patricia Delafosse, Xavier Troussard, Anne Moreau, Olivier Hermine, Marc Maynadié. Survival benefit of mantle cell lymphoma patients enrolled in clinical trials; a joint study from the LYSA group and French cancer registries. Journal of Cancer Research and Clinical Oncology. (2018) 629–635. inserm-01624838
Franck Morschhauser, Nathan Fowler, Pierre Feugier, Reda Bouabdallah, Hervé Tilly, M Palomba, Christophe Fruchart, Edward Libby, René-Olivier Casasnovas, Ian Flinn, Corinne Haioun, Hervé Maisonneuve, Loic Ysebaert, Nancy Bartlett, Kamal Bouabdallah, Pauline Brice, Vincent Ribrag, Nicolas Daguindau, Steven Le Gouill, Gian Pica, Alejandro Martin Garcia-Sancho, Armando Lopez-Guillermo, Jean-François Larouche, Kiyoshi Ando, Maria Gomes da Silva, Marc André, Pierre Zachee, Laurie Sehn, Kensei Tobinai, Guillaume Cartron, David Liu, Jianming Wang, Luc Xerri, Gilles Salles. Rituximab plus Lenalidomide in Advanced Untreated Follicular Lymphoma. New England Journal of Medicine. (2018) 934 – 947. inserm-01934589
Thierry Lamy, Gandhi Damaj, Pierre Soubeyran, Emmanuel Gyan, Guillaume Cartron, Krimo Bouabdallah, Rémy Gressin, Jérôme Cornillon, Anne Banos, Katell Le Du, Mohamed Benchalal, Marie-Pierre Moles, Steven Le Gouill, Joel Fleury, Pascal Godmer, Hervé Maisonneuve, Eric Deconinck, Roch Houot, Kamel Laribi, Jean Pierre Marolleau, Olivier Tournilhac, Bernard Branger, Anne Devillers, Philippe Vuilliez, Thierry Fest, Philippe Colombat, Valérie Costes, Vanessa Szablewski, Marie C. Béné, Vincent Delwail. R-CHOP 14 with or without radiotherapy in non-bulky limited-stage diffuse large B-cell lymphoma (DLBCL). Blood. (2018) 174-181. hal-01635792
Michael Wang, Simon Rule, Pier Zinzani, Andre Goy, Olivier Casasnovas, Stephen Smith, Gandhi Damaj, Jeanette Doorduijn, Thierry Lamy, Franck Morschhauser, Carlos Panizo, Bijal Shah, Andrew Davies, Richard Eek, Jehan Dupuis, Eric Jacobsen, Arnon Kater, Steven Le Gouill, Lucie Oberic, Taduesz Robak, Todd Covey, Richa Dua, Ahmed Hamdy, xin huang, Raquel Izumi, Priti Patel, Wayne Rothbaum, Greg Slatter, Wojciech Jurczak. Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial. Lancet. (2018) 659-667. inserm-01980627
Patricia Gomez-Bougie, Sophie Maïga, Benoit Tessoulin, Jessie Bourcier, Antoine Bonnet, Manuel Rodriguez, Steven Le Gouill, Cyrille Touzeau, Philippe Moreau, Catherine Pellat-Deceunynck, Martine Amiot. BH3-mimetic toolkit guides the respective use of BCL2 and MCL1 BH3-mimetics in myeloma treatment. Blood. (2018) Epub ahead of print. inserm-01900681
Cyrille Touzeau, Paulo Maciag, Martine Amiot, Philippe Moreau. Targeting Bcl-2 for the treatment of multiple myeloma. Leukemia. (2018) 1899 – 1907. inserm-01885190
Cyrille Touzeau, Philippe Moreau. Ixazomib in the management of relapsed multiple myeloma. Future Oncology. (2018) 2013 – 2020. inserm-01934497
Benoit Tessoulin, Agnès Moreau-Aubry, Géraldine Descamps, Patricia Gomez-Bougie, Sophie Maiga, Alban Gaignard, David Chiron, Emmanuelle Ménoret, Steven Le Gouill, Philippe Moreau, Martine Amiot, Catherine Pellat-Deceunynck. Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways. Journal of Hematology & Oncology. (2018) 137. inserm-01958772
Anne Lok, Géraldine Descamps, Benoit Tessoulin, David Chiron, Marion Eveillard, Catherine Godon, Yannick Le Bris, Astrid Vabret, Céline Bellanger, Laurent Maillet, Sophie Barillé-Nion, Marc Gregoire, Jean-François Fonteneau, Steven Le Gouill, Philippe Moreau, Frederic Tangy, Martine Amiot, Agnès Moreau-Aubry, Catherine Pellat-Deceunynck. p53 regulates CD46 expression and measles virus infection in myeloma cells. Blood Advances. (2018) 3492-3505. inserm-01957487
Pierre Sujobert, Yannick Le Bris, Laurence De Leval, Audrey Gros, Jean Philippe Merlio, Cedric Pastoret, Sarah Huet, Clémentine Sarkozy, Frederic Davi, Mary Callanan, Catherine Thieblemont, David Sibon, Vahid Asnafi, Claude Preudhomme, Philippe Gaulard, Fabrice Jardin, Gilles Salles, Elizabeth Macintyre. Definition of a minimal genes set for mature lymphoid blood diseases. Hématologie. (2018) 27-59. hal-01870189
Pierre Peterlin, Joëlle Gaschet, Thierry Guillaume, Alice Garnier, Marion Eveillard, Amandine Le Bourgeois, Michel Chérel, Camille Debord, Yannick Le Bris, Olivier Theisen, Béatrice Mahé, Viviane Dubruille, Soraya Wuilleme, Catherine Godon, Cyrille Touzeau, Thomas Gastinne, Nicolas Blin, Anne Lok, Antoine Bonnet, Steven Le Gouill, Philippe Moreau, Marie Béné, Patrice Chevallier. Fms-like Tyrosine Kinase 3 Ligand Concentration Kinetic Profile during Induction Is Strongly Predictive of Survivals in AML: Results of the FLAM/Flal Study. Blood (2018) 1484. inserm-02341909
Steven Le Gouill, René-Olivier Casasnovas. Interim PET-driven strategy in de novo diffuse large B-cell lymphoma: do we trust the driver ?. Blood. (2017) 3059-3070. inserm-01556383
Shaji Kumar, Jonathan Kaufman, Cristina Gasparetto, Joseph Mikhael, Ravi Vij, Brigitte Pegourie, Lofti Benboubker, Thierry Facon, Martine Amiot, Philippe Moreau, Elizabeth Punnoose, Stefanie Alzate, Martin Dunbar, Tu Xu, Suresh K. Agarwal, Sari Heitner Enschede, Joel D. Leverson, Jeremy A. Ross, Paulo C. Maciag, Maria Verdugo, Cyrille Touzeau. Efficacy of venetoclax as targeted therapy for relapsed/refractory t(11;14) multiple myeloma. Blood. (2017) 2401-2409. inserm-01631468
Laurence Lodé, Audrey Ménard, Laurent Flet, Steven Richebourg, Marion Loirat, Marion Eveillard, Yannick Le Bris, Catherine Godon, Olivier Theisen, Anne-Laure Gagez, Guillaume Cartron, Thérèse Commes-Maerten, Bruno Villemagne, Odile Luycx, Pascal Godmer, Catherine Pellat-Deceunynck, Thierry Soussi, Marie Béné, Jacques Delaunay, Pierre Peterlin. Emergence and evolution of TP53 mutations are a key feature of disease progression in myelodysplastic patients with lower-risk del(5q) treated with lenalidomide.. Haematologica. (2017) Epub ahead of print. inserm-01691580
Joel Leverson, Deepak Sampath, Andrew Souers, Saul Rosenberg, Wayne Fairbrother, Martine Amiot, Marina Konopleva, Anthony Letai. Found in Translation: How Preclinical Research Is Guiding the Clinical Development of the BCL2-Selective Inhibitor Venetoclax. Cancer Discovery / Cancer Discov. (2017) Epub ahead of print. inserm-01638832
Jeroen Guikema, Martine Amiot, Eric Eldering. Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer. Expert Opinion on Therapeutic Targets. (2017) 767-779. inserm-01558188
Hanna Karvonen, David Chiron, Wilhelmiina Niininen, Sara Ek, Mats Jerkeman, Elaheh Moradi, Matti Nykter, Caroline Heckman, Olli Kallioniemi, Astrid Murumägi, Daniela Ungureanu. Crosstalk between ROR1 and BCR pathways defines novel treatment strategies in mantle cell lymphoma. Blood. (2017) 2257-2268. inserm-01654519
Clément Bailly, Rodolphe Leforestier, Bastien Jamet, Thomas Carlier, Mickael Bourgeois, François Guérard, Cyrille Touzeau, Philippe Moreau, Michel Chérel, Françoise Kraeber-Bodéré, Caroline Bodet-Milin. PET Imaging for Initial Staging and Therapy Assessment in Multiple Myeloma Patients. International Journal of Molecular Sciences. (2017) pii: E445. inserm-01500327
Benoit Tessoulin, Marion Eveillard, Anne Lok, David Chiron, Philippe Moreau, Martine Amiot, Agnès Moreau-Aubry, Steven Le Gouill, Catherine Pellat-Deceunynck. p53 dysregulation in B-cell malignancies: More than a single gene in the pathway to hell. Blood Reviews. (2017) [Epub ahead of print]. inserm-01493742
Antonin Papin, Steven Le Gouill, David Chiron. Rationale for targeting tumor cells in their microenvironment for mantle cell lymphoma treatment. Leukemia & lymphoma. (2017) Epub ahead of print. inserm-01655227
Aline Clavert, Zinaida Peric, Eolia Brissot, Florent Malard, Thierry Guillaume, Jacques Delaunay, Viviane Dubruille, Steven Le Gouill, Beatrice Mahe, Thomas Gastinne, Nicolas Blin, Jean-Luc Harousseau, Philippe Moreau, Noel Milpied, Mohamad Mohty, Patrice Chevallier. Late Complications and Quality of Life after Reduced-Intensity Conditioning Allogeneic Stem Cell Transplantation.. Biology of Blood and Marrow Transplantation. (2017) 140-146. hal-01568571
Ali Younes, Gilles Montavon, Sebastien G. Gouin, Emy Andre-Joyaux, Roxane Peumery, Thibaut Chalopin, Cyrille Alliot, Marcel Mokili, Julie Champion, David Deniaud. Investigation of a new `’ N2S2O2 `’ chelating agent with high Po(IV) affinity. Chemical Communications. (2017) 6492-6495. hal-02141226
Ali Younes, Cyrille Alliot, Marcel Mokili, Gilles Montavon. Is Polonium-210 a Good Indicator for Anthropogenic Radioactivity?. DOI 10.1089/cbr.2018.2496. (2017) 356-360. hal-02004388