2020 2019 2018 2017


Marie Deleers, Adrien Breiman, Valery Daubie, Carine Maggetto, Isabelle Barreau, Tatiana Besse, Beatrice Clemenceau, Nathalie Ruvoen-Clouet, Jean-Francois Fils, Evelyne Maillart, Virginie Doyen, Bhavna Mahadeb, Jacques Jani, Philippe Van Der Linden, Mieke Cannie, Nabil Hayef, Francis Corazza, Jacques Le Pendu, and Hanane El Kenz. Covid-19 and blood groups: ABO antibody levels may also matter. International Journal of Infectious Diseases, December 2020. inserm-03094253.

Lea Dubreuil, Bercelin Maniangou, Patrice Chevallier, Agnes Quemener, Nolwenn Legrand, Marie C Bene, Catherine Willem, Gaelle David, Mehdi Alizadeh, Dhon Romeo Makanga, Anne Cesbron, Ketevan Gendzekhadze, Katia Gagne, and Christelle Retiere. Centromeric KIR AA Individuals Harbor Particular KIR Alleles Conferring Bene cial NK Cell Features with Implications in Haplo-Identical Hematopoietic Stem Cell Transplantation. Cancers, December 2020. inserm-03035170.

Piera Filomena Fiore, Sabina Di Matteo, Nicola Tumino, Francesca Romana Mariotti, Gabriella Pietra, Selene Ottonello, Simone Negrini, Barbara Bottazzi, Lorenzo Moretta, Erwan Mortier, and Bruno Azzarone. Interleukin-15 and cancer: some solved and many unsolved questions. Journal for Immunotherapy of Cancer, November 2020. inserm-03013809.

Dhon Romeo Makanga, Francesca Da Rin de Lorenzo, Gaelle David, Catherine Willem, Lea Dubreuil, Nolwenn Legrand, Thierry Guillaume, Pierre Peterlin, Amandine Lebourgeois, Marie Christine Bene, Alice Garnier, Patrice Chevallier, Ketevan Gendzekhadze, Anne Cesbron, Katia Gagne, Beatrice Clemenceau, and Christelle Retiere. Genetic and Molecular Basis of Heterogeneous NK Cell Re-sponses against Acute Leukemia. Cancers, July 2020. inserm-02913794.

Sophie Vantyghem, Pierre Peterlin, Sylvain Thepot, Audrey Menard, Viviane Dubruille, Camille Debord, Thierry Guillaume, Alice Garnier, Amandine Le Bourgeois, Soraya Wuilleme, Catherine Godon, Olivier Theisen, Marion Eveillard, Jacques Delaunay, Herv Maisonneuve, Nadine Morineau, Bruno Villemagne, Stephane Vigouroux, Francois Subiger, Elsa Lestang, Marion Loirat, Anne Parcelier, Pascal Godmer, Melanie Mercier, Adrien Trebouet, Damien Luque Paz, Ronan Le Calloch, Lena g Le Clech, Celine Bossard, Anne Moreau, Valerie Ugo, Mathilde Hunault, Philippe Moreau, Steven Le Gouill, Patrice Chevallier, Marie C Bene, and Yannick Le Bris. Diagnosis and prognosis are comforted by integrated assessment of next-generation sequencing in chronic myeloid malignancies. A real-life study. Haematologica, April 2020. inserm-02552097.

Celine Vandamme, Rebecca Xicluna, Leslie Hesnard, Marie Devaux, Nicolas Jaulin, Mickael Guilbaud, Johanne Le Du , Celia Couzinie, Philippe Moullier, Xavier Saulquin, and Oumeya Adjali. Tetramer-Based Enrichment of Preexisting Anti-AAV8 CD8 + T Cells in Human Donors Allows the Detection of a T EMRA Subpopulation. Frontiers in Immunology, January 2020. inserm-02447186.

Christelle Harly, Devin Kenney, Yueqiang Wang, Yi Ding, Yongge Zhao, Parirokh Awasthi, and Avinash Bhandoola. A Shared Regulatory Element Controls the Initiation of Tcf7 Expression During Early T Cell and Innate Lymphoid Cell Developments. Frontiers in Immunology, 2020. inserm-02541580.

Jeanne Perroteau, Benjamin Navet, Marie-Claire Devilder, Leslie Hesnard, Emmanuel Scotet, Laurent Gapin, Xavier Saulquin, and Laetitia Gautreau-Rolland. Contribution of the SYK Tyrosine kinase expression to human iNKT self-reactivity. European Journal of Immunology, 2020. inserm-02874033.

Christelle Harly and Avinash Bhandoola. Switch hitter: Bcl11b in T cells and ILC2s. Journal of Experimental Medicine, 2020. inserm-02541576.

Kervarrec, M Tallegas, D. Schrama, R. Houben, J. Ollier, B. Clemenceau, H. Vie, A Touze, M. Samimi, and S. Guyetant. BerEP4 positivity in Merkel cell carcinoma: a potential diagnosis pitfall. Journal of the European Academy of Dermatology and Venereology, 2020. inserm-02908448.

Yannick Le Bris, Florence Magrangeas, Anne Moreau, David Chiron, Catherine Guerin-Charbonnel, Olivier Theisen, Olivier Pichon, Danielle Canioni, Barbara Burroni, Herv Maisonneuve, Catherine Thieblemont, Lucie Oberic, Emmanuel Gyan, Catherine Pellat-Deceunynck, Olivier Hermine, Marie-Helene Delfau-Larue, Benoit Tessoulin, Marie C Bene, Stephane Minvielle, and Steven Le Gouill. Whole genome copy number analysis in search of new prognostic biomarkers in rst line treatment of mantle cell lymphoma. A study by the LYSA group. Hematological Oncology, 2020. inserm-02874026.

Marion Rabe, Solenne Dumont, Arturo Alvarez-Arenas, Hicham Janati, Juan Belmonte-Beitia, Gabriel F Calvo, Christelle Thibault-Carpentier, Quentin Sery, Cynthia Chauvin, Noemie Joalland, Floriane Briand, Stephanie Blandin, Emmanuel Scotet, Claire Pecqueur, Jean Clairambault, Lisa Oliver, Victor Perez-Garcia, Arulraj M Nadaradjane, Pierre-Francois Cartron, Catherine Gratas, and Francois Vallette. Identification of a transient state during the acquisition of temozolomide resistance in glioblastoma. Cell Death and Disease, January 2020. hal-02429194.

Lucine Marotte, Sylvain Simon, Virginie Vignard, Emilie Dupre, Malika Gantier, Jonathan Cruard, Jean-Baptiste Alberge, Melanie Hussong, Cecile Deleine, Jean-Marie Heslan, Jonathan Shaffer, Tiffany Beauvais, Joelle Gaschet, Emmanuel Scotet, Delphine Fradin, Anne Jarry, Tuan Nguyen, and Nathalie Labarriere. Increased antitumor e cacy of PD-1- de cient melanoma-speci c human lymphocytes. Journal for Immunotherapy of Cancer, January 2020. inserm-02481085.

Raphael Carapito, Ismaïl Aouadi, Angelique Pichot, Perrine Spinnhirny, Aurore Morlon, Irina Kotova, Cecile Macquin, Veronique Rolli, Anne Cesbron, Katia Gagne, Machteld Oudshoorn, Bronno Van Der Holt, Myriam Labalette, Eric Spierings, Christophe Picard, Pascale Loiseau, Ryad Tamouza, Antoine Toubert, Anne Parissiadis, Valerie Dubois, Catherine Paillard, Myriam Maumy-Bertrand, Frederic Bertrand, Peter A. von dem Borne, Jurgen H. E. Kuball, Mauricette Michallet, Bruno Lioure, Regis Peffault De Latour, Didier Blaise, Jan J. Cornelissen, Ibrahim Yakoub Agha, Frans H.J. Claas, Philippe Moreau, Dominique Charron, Mohamad Mohty, Yasuo Morishima, Gerard Socie, and Seiamak Bahram. Compatibility at amino acid position 98 of MICB reduces the incidence of graft-versus host disease in conjunction with the CMV status. Bone Marrow Transplantation, 2020. inserm-02545513

Noemie Joalland and Emmanuel Scotet. Emerging Challenges of Preclinical Models of Anti-tumor Immunotherapeutic Strategies Utilizing V 9V 2 T Cells. Frontiers in Immunology, 2020. inserm-02908442.

Nolwenn Legrand, Gaelle David, Audrey Rodallec, Aurelie Gaultier, Dominique Salmon, Anne Cesbron, Linda Wittkop, Francois Ra , Ketevan Gendzekhadze, Christelle Retiere, Clotilde Allavena, and Katia Gagne. European HIV-HCV co-infected individuals Short title: HLA-C and sponta-neous clearance in HIV-HCV coinfection. Clinical and Experimental Immunology, 2020. inserm-03063756.

Erwan Mortier, Averil Ma, Barbara A Malynn, and Markus F Neurath. Modulating Cytokines as Treatment for Autoimmune. Diseases and Cancer, December 2020. inserm-03079706.

Carole Guillonneau, Ignacio Anegon, Erwan Mortier, and Agnes Quemener. Mutated Interleukin-34 (IL-34) Polypeptides and Uses Thereof in Therapy, [Brevet : WO2020148338] July 2020. inserm-02991886.

Xavier Saulquin. Methods and Kits for Generating and Selecting a Variant of a Binding Protein with Increased Binding Affinity and/or Specificity, [Brevet : PCT/EP2020/050646] 2020.  inserm-02547893.

Xavier Saulquin. Human Monoclonal Antibodies Binding to HLA-A2, [Brevet : PCT/EP2020/050649] 2020. inserm-02547885


Yoan Brissonnet, Coralie Assailly, Amelie Saumonneau, Julie Bouckaert, Mike Maillasson, Clemence Petitot, Benoit Roubinet, Blanka Didak, Ludovic Landemarre, Clarisse Bridot, Ralf Blossey, David Deniaud, Xibo Yan, Julien Bernard, Charles Tellier, Cyrille Grandjean, Franck Daligault, Sebastien G. Gouin. Multivalent Thiosialosides and Their Synergistic Interaction with Pathogenic Sialidases. Chemistry – A European Journal. (2019) 2358-2365. hal-02140863

Louise Bouard, Caroline Bodet-Milin, Clément Bailly, Thierry Guillaume, Pierre Peterlin, Alice Garnier, Amandine Bourgeois, Béatrice Mahé, Viviane Dubruille, Nicolas Blin, Cyrille Touzeau, Thomas Gastinne, Anne Lok, Antoine Bonnet, Marie Bene, Steven Gouill, Philippe Moreau, Françoise Kraeber-Bodéré, Patrice Chevallier. Deauville Scores 4 or 5 Assessed by Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Early Post-Allotransplant Is Highly Predictive of Relapse in Lymphoma Patients. Biology of Blood and Marrow Transplantation. (2019) 906-911. inserm-01981440

Pierre Peterlin, Joëlle Gaschet, Thierry Guillaume, Alice Garnier, Marion Eveillard, Amandine Le Bourgeois, Michel Chérel, Camille Debord, Yannick Le Bris, Olivier Theisen, Béatrice Mahé, Viviane Dubruille, Catherine Godon, Nelly Robillard, Soraya Wuilleme, Cyrille Touzeau, Thomas Gastinne, Nicolas Blin, Anne Lok, Antoine Bonnet, Steven Le Gouill, Philippe Moreau, Marie-Christine Béné, Patrice Chevallier. FLT3 ligand plasma levels in acute myeloid leukemia. Haematologica. (2019) Epub ahead of print. inserm-01993986

Thierry Guillaume, Virginie Dehame, Patrice Chevallier, Pierre Peterlin, Alice Garnier, Marc Grégoire, Edward Pichinuk, Daniel Rubinstein, Daniel Wreschner. Targeting cell-bound MUC1 on myelomonocytic, monocytic leukemias and phenotypically defined leukemic stem cells with anti-SEA module antibodies. Experimental Hematology. (2019) 97-108. inserm-01994077

Catherine Willem, Dhon Roméo Makanga, Thierry Guillaume, Bercelin Maniangou, Nolwenn Legrand, Katia Gagne, Pierre Peterlin, Alice Garnier, Marie Béné, Anne Cesbron, Amandine Le Bourgeois, Patrice Chevallier, Christelle Retière. Impact of KIR/HLA Incompatibilities on NK Cell Reconstitution and Clinical Outcome after T Cell–Replete Haploidentical Hematopoietic Stem Cell Transplantation with Posttransplant Cyclophosphamide. Journal of Immunology. (2019) 2141-2152. inserm-02080762

Michael Dustin, Emmanuel Scotet, Daniel Olive. An X-ray Vision for Phosphoantigen Recognition. Immunity. (2019) 1026-1028. inserm-02102425

Marie-Claire Devilder, Melinda Moyon, Laetitia Gautreau-Rolland, Benjamin Navet, Jeanne Perroteau, Florent Delbos, Marie-Claude Gesnel, Richard Breathnach, Xavier Saulquin. Ex vivo evolution of human antibodies by CRISPR-X: from a naive B cell repertoire to affinity matured antibodies. BMC Biotechnology. (2019). inserm-02117156

Christelle Harly, Devin Kenney, Gang Ren, Binbin Lai, Tobias Raabe, Qi Yang, Margaret Cam, Hai-Hui Xue, Keji Zhao, Avinash Bhandoola. The transcription factor TCF-1 enforces commitment to the innate lymphoid cell lineage. Nature Immunology. (2019) Epub ahead of print. inserm-02265827

Pierre Peterlin, Joëlle Gaschet, Thierry Guillaume, Alice Garnier, Marion Eveillard, Amandine Le Bourgeois, Michel Chérel, Camille Debord, Yannick Le Bris, Olivier Theisen, Béatrice Mahé, Viviane Dubruille, Catherine Godon, Nelly Robillard, Soraya Wuilleme, Cyrille Touzeau, Thomas Gastinne, Nicolas Blin, Anne Lok, Antoine Bonnet, Steven Le Gouill, Philippe Moreau, Marie-C Béné, Patrice Chevallier. FLT3 ligand plasma levels have no impact on outcomes after allotransplant in acute leukemia. Cytokine. (2019) 85-87. inserm-02266372

Rui Sousa, Adèle Laurent, Agnès Quéméner, Erwan Mortier, Jean-Yves Le Questel. Mechanistic and Structural Insights on the IL-15 System through Molecular Dynamics Simulations. Molecules (2019) 3261. inserm-02289307

Marie Frutoso, Erwan Mortier. NK Cell Hyporesponsiveness: More Is Not Always Better. International Journal of Molecular Sciences. (2019) 4514. inserm-02289319

Cynthia Chauvin, Noémie Joalland, Jeanne Perroteau, Ulrich Jarry, Laura Lafrance, Catherine Willem, Christelle Retiere, Lisa Oliver, Catherine Gratas, Laetitia Gautreau-Rolland, Xavier Saulquin, François Vallette, Henri Vie, Emmanuel Scotet, Claire Pecqueur. NKG2D controls natural reactivity of Vγ9Vδ2 T lymphocytes against mesenchymal glioblastoma cells. Clinical Cancer Research (2019). inserm-02316604

Agnès Quéméner, Sébastien Morisseau, Rui Sousa, Kilian Trillet, Mike Maillasson, Isabelle Leray, Yannick Jacques, Johann Dion, Isabelle Barbieux, Marie Frutoso, Adèle Laurent, Jean-Yves Le Questel, Erwan Mortier. IL-15Rα membrane-anchorage either in cis or in trans is required for stabilization of IL-15 and optimal signaling. Journal of Cell Science (2019). inserm-02345095


Régine Vivien, Soraya Saïagh, Philippe Lemarre, Valérie Chabaud, Béline Jesson, Catherine Godon, Ulrich Jarry, Thierry Guillaume, Patrice Chevallier, Henri Vié, Béatrice Clémenceau. The doubling potential of T lymphocytes allows clinical-grade production of a bank of genetically modified monoclonal T-cell populations. Cytotherapy. (2018) 436 – 452. inserm-01813104

Bercelin Maniangou, Christelle Retière, Katia Gagne. Next-generation sequencing technology a new tool for killer cell immunoglobulin-like receptor allele typing in hematopoietic stem cell transplantation : Séquençage nouvelle génération, un nouvel outil pour typer les allèles killer cell immunoglobulin-like receptor en greffes de cellules souches hématopoïétiques. Transfusion Clinique et Biologique. (2018) 87 – 89. inserm-01807147

Lola Boutin, Emmanuel Scotet. Towards Deciphering the Hidden Mechanisms That Contribute to the Antigenic Activation Process of Human Vγ9Vδ2 T Cells. Frontiers in Immunology. (2018) 1-1. inserm-01807705

Trudy Straetemans, Guido Kierkels, Ruud Doorn, Koen Jansen, Sabine Heijhuurs, Joao dos Santos, Anna van Muyden, Henri Vié, Béatrice Clémenceau, Reinier Raymakers, Moniek de Witte, Zsolt Sebestyén, Jürgen Kuball. GMP-Grade Manufacturing of T Cells Engineered to Express a Defined γδTCR. Frontiers in Immunology. (2018) 1062. inserm-01823708

Christelle Retière, Catherine Willem, Thierry Guillaume, Henri Vié, Laetitia Gautreau-Rolland, Emmanuel Scotet, Xavier Saulquin, Katia Gagne, Marie Béné, Berthe-Marie Imbert, Béatrice Clémenceau, Pierre Peterlin, Alice Garnier, Patrice Chevallier. Impact on early outcomes and immune reconstitution of high- dose post-transplant cyclophosphamide vs anti-thymocyte globulin after reduced intensity conditioning peripheral blood stem cell allogeneic transplantation. Oncotarget. (2018) 11451 – 11464. inserm-01737944

Marie-Claire Devilder, Melinda Moyon, Xavier Saulquin, Laetitia Gautreau-Rolland. Generation of Discriminative Human Monoclonal Antibodies from Rare Antigen-specific B Cells Circulating in Blood. Journal of visualized experiments : JoVE. (2018) e56508. inserm-01745629

Marie Frutoso, Sébastien Morisseau, Fella Tamzalit, Agnès Quéméner, Dihia Meghnem, Isabelle Leray, Yannick Jacques, Erwan Mortier. Emergence of NK Cell Hyporesponsiveness after Two IL-15 Stimulation Cycles. Journal of Immunology. (2018) Epub ahead of print. inserm-01805185

Oisín Huhn, Olympe Chazara, Martin Ivarsson, Christelle Retière, Timothy Venkatesan, Paul Norman, Hugo Hilton, Jyothi Jayaraman, James Traherne, John Trowsdale, Mitsutero Ito, Christiane Kling, Peter Parham, Hormas Ghadially, Ashley Moffett, Andrew Sharkey, Francesco Colucci. High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia. Journal of Immunology. (2018) 2593-2601. inserm-01968722

Francesco Saraceni, Myriam Labopin, Rose-Marie Hamladji, Ghulam Mufti, Gerard Socie, Avichai Shimoni, Jeremy Delage, Eric Deconinck, Patrice Chevallier, Didier Blaise, Jaime Sanz, Anne Huynh, Edouard Forcade, Bipin N. Savani, Mohamad Mohty, Arnon Nagler, Acute Leukemia Working Party Europ. Thiotepa-busulfan-fludarabine compared to busulfan-fludarabine for sibling and unrelated donor transplant in acute myeloid leukemia in first remission. Oncotarget. (2018) 3379-3393. hal-02143546

Salyka Sengsayadeth, Myriam Labopin, Ariane Boumendil, Juergen Finke, Arnold Ganser, Matthias Stelljes, Gerhard Ehninger, Dietrich Beelen, Dietger Niederwieser, Didier Blaise, Peter Dreger, Ghulam Mufti, Patrice Chevallier, Audrey Mailhol, Katie S. Gatwood, Norbert Gorin, Jordi Esteve, Fabio Ciceri, Frederic Baron, Christoph Schmid, Sebastian Giebel, Mohamad Mohty, Bipin N. Savani, Arnon Nagler. Transplant Outcomes for Secondary Acute Myeloid Leukemia: Acute Leukemia Working Party of the European Society for Blood and Bone Marrow Transplantation Study. Biology of Blood and Marrow Transplantation. (2018) 1406-1414. hal-02143562

Raynier Devillier, Myriam Labopin, Patrice Chevallier, Marie-Pierre Ledoux, Gerard Socie, Anne Huynh, Jean-Henri Bourhis, Jean-Yves Cahn, Gabrielle Roth-Guepin, Ghulam Mufti, Deborah Desmier, Mauricette Michallet, Nathalie Fegueux, Fabio Ciceri, Frederic Baron, Didier Blaise, Arnon Nagler, Mohamad Mohty. Impact of antithymocyte globulin doses in reduced intensity conditioning before allogeneic transplantation from matched sibling donor for patients with acute myeloid leukemia: a report from the acute leukemia working party of European group of Bone Marrow Transplantation. Bone Marrow Transplantation. (2018) 431-437. hal-02143554

Emilie Dugast, Gaëlle David, Romain Oger, Richard Danger, Jean-Paul Judor, Katia Gagne, Mélanie Chesneau, Nicolas Degauque, Jean-Paul Soulillou, Pascale Paul, Christophe Picard, Pierrick Guerif, Sophie Conchon, Magali Giral, Nadine Gervois, Christelle Retière, Sophie Brouard. Corrigendum: Broad Impairment of Natural Killer Cells From Operationally Tolerant Kidney Transplanted Patients. Frontiers in Immunology. (2018) 589. inserm-01811913

Jocelyn Ollier, Thibault Kervarrec, Mahtab Samimi, Houssem Benlalam, Pascal Aumont, Régine Vivien, Antoine Touzé, Nathalie Labarrière, Henri Vié, Béatrice Clémenceau. Merkel cell carcinoma and cellular cytotoxicity: sensitivity to cellular lysis and screening for potential target antigens suitable for antibodydependent cellular cytotoxicity. Cancer Immunology, Immunotherapy. (2018) Epub ahead of print. inserm-01807689

Noémie Joalland, Cynthia Chauvin, Lisa Oliver, François Vallette, Claire Pecqueur, Ulrich Jarry, Emmanuel Scotet. IL-21 Increases the Reactivity of Allogeneic Human Vγ9Vδ2 T Cells Against Primary Glioblastoma Tumors. Journal of immunotherapy : official journal of the Society for Biological Therapy. (2018) 224-231. inserm-01804994

Ulrich Jarry, Noémie Joalland, Cynthia Chauvin, Béatrice Clémenceau, Claire Pecqueur, Emmanuel Scotet. Stereotactic Adoptive Transfer of Cytotoxic Immune Cells in Murine Models of Orthotopic Human Glioblastoma Multiforme Xenografts. Journal of visualized experiments : JoVE. (2018) 1(139). inserm-01885088

Pierre Peterlin, Joëlle Gaschet, Thierry Guillaume, Alice Garnier, Marion Eveillard, Amandine Le Bourgeois, Michel Chérel, Camille Debord, Yannick Le Bris, Olivier Theisen, Béatrice Mahé, Viviane Dubruille, Soraya Wuilleme, Catherine Godon, Cyrille Touzeau, Thomas Gastinne, Nicolas Blin, Anne Lok, Antoine Bonnet, Steven Le Gouill, Philippe Moreau, Marie Béné, Patrice Chevallier. Fms-like Tyrosine Kinase 3 Ligand Concentration Kinetic Profile during Induction Is Strongly Predictive of Survivals in AML: Results of the FLAM/Flal Study. Blood (2018) 1484. inserm-02341909


Stéphanie Dirou, Arnaud Chambellan, Patrice Chevallier, Patrick Germaud, Guillaume Lamirault, Pierre-Antoine Gourraud, Bastien Perrot, Béatrice Delasalle, Bastien Forestier, Thierry Guillaume, Pierre Peterlin, Alice Garnier, Antoine Magnan, François-Xavier Blanc, Patricia Lemarchand. Deconditioning, fatigue and impaired quality of life in long-term survivors after allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplantation. (2017) Epub ahead of print. inserm-01684314

Sébastien Küry, Geeske van Woerden, Thomas Besnard, Martina Onori, Xénia Latypova, Meghan Towne, Megan Cho, Trine Prescott, Melissa Ploeg, Stephan Sanders, Holly Stessman, Aurora Pujol, Ben Distel, Laurie Robak, Jonathan Bernstein, Anne-Sophie Denommé-Pichon, Gaëtan Lesca, Elizabeth Sellars, Jonathan Berg, Wilfrid Carré, Øyvind Busk, Bregje Van Bon, Jeff Waugh, Matthew Deardorff, George Hoganson, Katherine Bosanko, Diana Johnson, Tabib Dabir, Øystein Lunde Holla, Ajoy Sarkar, Kristian Tveten, Julitta De Bellescize, Geir Braathen, Paulien Terhal, Dorothy Grange, Arie Van Haeringen, Christina Lam, Ghayda Mirzaa, Jennifer Burton, Elizabeth Bhoj, Jessica Douglas, Avni Santani, Addie Nesbitt, Katherine Helbig, Marisa Andrews, Amber Begtrup, Sha Tang, Koen L.I. van Gassen, Jane Juusola, Kimberly Foss, Gregory Enns, Ute Moog, Katrin Hinderhofer, Nagarajan Paramasivam, Sharyn Lincoln, Brandon Kusako, Pierre Lindenbaum, Eric Charpentier, Catherine Nowak, Elouan Cherot, Thomas Simonet, Claudia A.L. Ruivenkamp, Sihoun Hahn, Catherine Brownstein, Fan Xia, Sébastien Schmitt, Wallid Deb, Dominique Bonneau, Mathilde Nizon, Delphine Quinquis, Jamel Chelly, Gabrielle Rudolf, Damien Sanlaville, Philippe Parent, Brigitte Gilbert-Dussardier, Annick Toutain, Vernon Sutton, Jenny Thies, Lisenka E.L.M. Peart-Vissers, Pierre Boisseau, Marie Vincent, Andreas Grabrucker, Christèle Dubourg, Undiagnosed Diseases Network, Wen-Hann Tan, Nienke Verbeek, Martin Granzow, Gijs W.E. Santen, Jay Shendure, Bertrand Isidor, Laurent Pasquier, Richard Redon, Yaping Yang, Matthew State, Tjitske Kleefstra, Benjamin Cogné, GEM HUGO, Deciphering Study, Slavé Petrovski, Kyle Retterer, Evan Eichler, Jill Rosenfeld, Pankaj Agrawal, Stéphane Bézieau, Sylvie Odent, Ype Elgersma, Sandra Mercier. De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability. American Journal of Human Genetics. (2017) 768 – 788. inserm-01813739

Raphaëlle Riou, Céline Bressollette-Bodin, David Boutoille, Katia Gagne, Audrey Rodallec, Maeva Lefebvre, François Raffi, David Senitzer, Berthe-Marie Imbert-Marcille, Christelle Retière. Severe Symptomatic Primary Human Cytomegalovirus Infection despite Effective Innate and Adaptive Immune Responses. Journal of Virology. (2017) e02245-16. inserm-01805573

Raphael Carapito, Martina Konantz, Catherine Paillard, Zhichao Miao, Angélique Pichot, Magalie Leduc, Yaping Yang, Katie Bergstrom, Donald Mahoney, Deborah Shardy, Ghada Alsaleh, Lydie Naegely, Aline Kolmer, Nicodème Paul, Antoine Hanauer, Véronique Rolli, Joëlle Müller, Elisa Alghisi, Loïc Sauteur, Cécile Macquin, Aurore Morlon, Consuelo Sebastia Sancho, Patrizia Amati-Bonneau, Vincent Procaccio, Anne-Laure Mosca-Boidron, Nathalie Marle, Nael Osmani, Olivier Lefebvre, Jacky Goetz, Sule Unal, Nurten Akarsu, Mirjana Radosavljevic, Marie-Pierre Chenard, Fanny Rialland, Audrey Grain, Marie-Christine Béné, Marion Eveillard, Vincent Vincent, Julien Guy, Laurence Faivre, Christel Thauvin-Robinet, Julien Thevenon, Kasiani Myers, Mark Fleming, Akiko Shimamura, Elodie Bottollier-Lemallaz, Eric Westhof, Claudia Lengerke, Bertrand Isidor, Seiamak Bahram. Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond–like features. Journal of Clinical Investigation. (2017) 4090-4103. hal-02171273

Pierre Boisseau, Camille Debord, Marion Eveillard, Agnès Quéméner, Marianne Sigaud, Mathilde Giraud, Patricia Talarmain, C. Thomas, G. Landeau, Stéphane Bezieau, Brigitte Pan-Petesch, Marie-Christine Béné, Marc Fouassier. Two novel variants of uncertain significance in GP9 associated with Bernard–Soulier syndrome: Are they true mutations? Platelets. (2017) 316 – 318. inserm-01807674

Mickael Vourc’h, Antoine Roquilly, Alexis Broquet, Gaëlle David, Philippe Hulin, Cédric Jacqueline, Jocelyne Caillon, Christelle Retière, Karim Asehnoune. Exoenzyme T Plays a Pivotal Role in the IFN-γ Production after Pseudomonas Challenge in IL-12 Primed Natural Killer Cells. Frontiers in Immunology. (2017) 1283 – 1283. inserm-01813287

Jocelyn Ollier, Régine Vivien, Henri Vié, Béatrice Clémenceau. Transfection of FcγRIIIa (CD16) Alone Can Be Sufficient To Enable Human αβTCR T Lymphocytes To Mediate Antibody-Dependent Cellular Cytotoxicity. ImmunoHorizons. (2017) 63 – 70. inserm-01563703

Henri Vié, Béatrice Clémenceau. Transfert adoptif de lymphocytes T : Adoptive transfer of T lymphocytes. Transfusion Clinique et Biologique. (2017) 256 – 262. inserm-01806932

E. Rederstorff, Gildas Réthoré, Pierre Weiss, Sophie Sourice, Sarah Beck-Cormier, E. Mathieu, Mike Maillasson, Yannick Jacques, S. Colliec-Jouault, B. Fellah, Jérome Guicheux, Claire Vinatier. Enriching a cellulose hydrogel with a biologically active marine exopolysaccharide for cell-based cartilage engineering. Journal of Tissue Engineering and Regenerative Medicine. (2017) 1152 – 1164. inserm-01818096

Dihia Meghnem, Sébastien Morisseau, Marie Frutoso, Kilian Trillet, Mike Maillasson, Isabelle Barbieux, Sarah Khaddage, Isabelle Leray, Markus Hildinger, Agnès Quéméner, Yannick Jacques, Erwan Mortier. Cutting Edge: Differential Fine-Tuning of IL-2- and IL-15- Dependent Functions by targeting their Common IL-2/15Rβ/γc Receptor. Journal of Immunology. (2017) 4563-4568. inserm-01524397

Bercelin Maniangou, Nolwenn Legrand, Mehdi Alizadeh, Ulysse Guyet, Catherine Willem, Gaëlle David, Eric Charpentier, Alexandre Walencik, Christelle Retière, Katia Gagne. Killer Immunoglobulin-Like Receptor Allele Determination Using Next-Generation Sequencing Technology. Frontiers in Immunology. (2017) 547. inserm-01807094

Alexis Rossignol, Véronique Bonnaudet, Béatrice Clémenceau, Henri Vié, Laurent Bretaudeau. A high-performance, non-radioactive potency assay for measuring cytotoxicity: A full substitute of the chromium-release assay targeting the regulatory-compliance objective. mAbs. (2017) 521 – 535. inserm-01806965

Agnès Quéméner, Mike Maillasson, Laurence Arzel, Benoit Sicard, Romy Vomiandry, Erwan Mortier, Didier Dubreuil, Yannick Jacques, Jacques Lebreton, Monique Mathé-Allainmat. Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization. Journal of Medicinal Chemistry. (2017) 6249-6272. inserm-01550121

Emilie Dugast, Gaëlle David, Romain Oger, Richard Danger, Jean-Paul Judor, Katia Gagne, Mélanie Chesneau, Nicolas Degauque, Pascale Paul, Christophe Picard, Pierrick Guerif, Sophie Conchon, Magali Giral, Nadine Gervois, Christelle Retière, Sophie Brouard. Broad Impairment of Natural Killer Cells from Operationally Tolerant Kidney Transplanted Patients. Frontiers in Immunology. (2017) 1721. hal-01712225

Kristell Oizel, Cynthia Chauvin, Lisa Oliver, Catherine Gratas, Fanny Geraldo, Ulrich Jarry, Emmanuel Scotet, Marion Rabe, Marie-Clotilde Alves-Guerra, Raluca Teusan, Fabien Gautier, Delphine Loussouarn, Vincent Compan, Jean-Claude Martinou, François Vallette, Claire Pecqueur. Efficient Mitochondrial Glutamine Targeting Prevails Over Glioblastoma Metabolic Plasticity. Clinical Cancer Research. (2017) Epub ahead of print. inserm-01595798

Julien Fleurence, Sophie Fougeray, Meriem Bahri, Denis Cochonneau, Béatrice Clémenceau, François Paris, Andras Heczey, Stéphane Birklé. Targeting-Acetyl-GD2 Ganglioside for Cancer Immunotherapy. Journal of Immunology Research. (2017) [Epub ahead of print]. inserm-01474322