Publications 2021 par équipe - CRCINA - Centre de Recherche en Cancérologie et Immunologie Nantes Angers

Equipe 01

Capitao M., Perrin J., Simon S., Gouard S., Chouin N., Bruchertseifer F., Morgenstern A., Rbah-Vidal L., Chérel M., Scotet E., Labarrière N., Guilloux Y., Gaschet J., Anti-Tumor Efficacy of PD-L1 Targeted Alpha-Particle Therapy in a Human Melanoma Xenograft Model. Cancers., 2021, 13(6):1256. Réf. HAL: inserm-03171640

David G., Willem C., Legrand N., Djaoud Z., Mérieau P., Walencik A., Guillaume T., Gagne K., Chevallier P., Retiere C., Deciphering the biology of KIR2DL3+ T lymphocytes that are associated to relapse in haploidentical HSCT. Scientific Reports., 2021, 11(1):15782. Réf. HAL: inserm-03317982

Dubreuil L., Chevallier P., Retiere C., Gagne K., Relevance of Polymorphic KIR and HLA Class I Genes in NK-Cell-Based Immunotherapies for Adult Leukemic Patients. Cancers., 2021, 13(15):3767. Réf. HAL: inserm-03317983

Johnnidis J. B, Muroyama Y., Foong Ngiow S., Chen Z., Manne S., Cai Z., Song S., Platt J. M, Schenkel J. M, Abdel-Hakeem M., Beltra J.C., Greenplate A. R, Ali M.A. A, Nzingha K., Giles J. R, Harly C., Attanasio J., Pauken K. E, Bengsch B., Paley M. A, Tomov V. T, Kurachi M., Vignali D. A A, Sharpe A. H, Reiner S. L, Bhandoola A., Johnson F. Bradley, Wherry E. John, Inhibitory signaling sustains a distinct early memory CD8 + T cell precursor that is resistant to DNA damage. Science Immunology., 2021, 6:eabe3702. Réf. HAL: inserm-03276330

Latypova X., Vincent M., Mollé A., Adebambo O. A, Fourgeux C., Khan T. N, Caro A., Rosello M., Orellana C., Niyazov D., Lederer D., Deprez M., Capri Y., Kannu P., Tabet A. Claude, Levy J., Aten E., Den Hollander N., Splitt M., Walia J., Immken L. L, Stankiewicz P., Mcwalter K., Suchy S., Louie R. J, Bell S., Stevenson R. E, Rousseau J., Willem C., Retiere C., Yang X.J., Campeau P. M, Martinez F., Rosenfeld J. A, Le Caignec C., Küry S., Mercier S., Moradkhani K., Conrad S., Besnard T., Cogné B., Katsanis N., Bézieau S., Poschmann J., Davis E. E, Isidor B., Haploinsufficiency of the Sin3/HDAC corepressor complex member SIN3B causes a syndromic intellectual disability/autism spectrum disorder. American Journal of Human Genetics., 2021, 108(5):929 – 941. Réf. HAL: inserm-03290535

Legrand N., David G., Rodallec A., Gaultier A., Salmon D., Cesbron A., Wittkop L., Raffi F., Gendzekhadze K., Retière C., Allavena C., Gagne K., Influence of HLA‐C environment on the spontaneous clearance of hepatitis C in European HIV–HCV co‐infected individuals. Clinical and Experimental Immunology., 2021, Online ahead of print. Réf. HAL: inserm-03136993

Lejeune M., Duray E., Peipp M., Clémenceau B., Baron F., Beguin Y., Caers J., Balancing the CD38 Expression on Effector and Target Cells in Daratumumab-Mediated NK Cell ADCC against Multiple Myeloma. Cancers., 2021, 13(12):3072. Réf. HAL: inserm-03290143

Makanga D. Roméo, Jullien M., David G., Legrand N., Willem C., Dubreuil L., Walencik A., Touzeau C., Gastinne T., Tessoulin B., Le Gouill S., Mahé B., Gagne K., Chevallier P., Clemenceau B., Retière C., Low number of KIR ligands in lymphoma patients favors a good rituximab-dependent NK cell response. OncoImmunology., 2021, 10(1):1936392. Réf. HAL: inserm-03287975

Makanga D. Roméo, Jullien M., David G., Legrand N., Willem C., Dubreuil L., Walencik A., Touzeau C., Gastinne T., Tessoulin B., Le Gouill S., Mahé B., Gagne K., Chevallier P., Clemenceau B., Retiere C., Low number of KIR ligands in lymphoma patients favors a good rituximab-dependent NK cell response. OncoImmunology., 2021, 10(1):1936392. Réf. HAL: inserm-03290251

Marotte L., Capitao M., Deleine C., Beauvais T., Cadiou G., Perrin J., Chérel M., Scotet E., Guilloux Y., Bruchertseifer F., Morgenstern A., Jarry A., Gaschet J., Labarrière N., Anti-tumor efficacy of a combination therapy with PD-L1 targeted alpha therapy and adoptive cell transfer of PD-1 deficient melanoma-specific human T-lymphocytes. OncoImmunology., 2021, 10(1):e1940676. Réf. HAL: inserm-03271847

Moradi S., Stankovic S., O’connor G. M, Pymm P., Maclachlan B. J, Faoro C., Retiere C., Sullivan L. C, Saunders P. M, Widjaja J., Cox-Livingstone S., Rossjohn J., Brooks A. G, Vivian J. P, Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C. Nature Communications., 2021, 12(1):2173. Réf. HAL: inserm-03290537

Smadja J., Quéméner A., Maillasson M., Sicard B., Leray A., Arzel L., Lebreton J., Mortier E., Dubreuil D., Mathe-Allainmat M., Rational modification, synthesis and biological evaluation of N-substituted phthalazinone derivatives designed to target interleukine-15 protein. Bioorganic & Medicinal Chemistry Letters., 2021, 39:116161. Réf. HAL: inserm-03214947

Equipe 02

Dréno B., Khammari A., Fortun A., Vignard V., Saiagh S., Beauvais T., Jouand N., Bercegay S., Simon S., Lang F., Labarrière N., Phase I/II clinical trial of adoptive cell transfer of sorted specific T cells for metastatic melanoma patients. Cancer Immunology, Immunotherapy., 2021, Online ahead of print. Réf. HAL: inserm-03260784

Equipe 03

Barret J.M., Nicolas A., Jarry A., Dubreuil O., Meseure D., Passat T., Perrial E., Deleine C., Champenois G., Gaillard S., Duchalais E., Ray-Coquard I., Lahmar M., Dumontet C., Bennouna J., Bossard C., Roman-Roman S., Prost J.F., The Expression of Anti-Müllerian Hormone Type II Receptor (AMHRII) in Non-Gynecological Solid Tumors Offers Potential for Broad Therapeutic Intervention in Cancer. Biology., 2021, 10(4):305. Réf. HAL: inserm-03287927

Breiman A., Ruvoën-Clouet N., Deleers M., Beauvais T., Jouand N., Rocher J., Bovin N., Labarrière N., El Kenz H., Le Pendu J., Low levels of natural anti-a-N-acetylgalactosamine (Tn) antibodies are associated with COVID-19. Frontiers in Microbiology., 2021, Online ahead of print. Réf. HAL: inserm-03122540

Denis Musquer M., Jouand N., Pere M., Lamer J.E., Bézieau S., Matysiak T., Faroux R., Caroli Bosc F.X., Rousselet M.C., Leclair F., Mosnier J.F., Toquet C., Gervois N., Bossard C., High-Density of FcγRIIIA+ (CD16+) Tumor-Associated Neutrophils in Metastases Improves the Therapeutic Response of Cetuximab in Metastatic Colorectal Cancer Patients, Independently of the HLA-E/CD94-NKG2A Axis. Frontiers in Oncology., 2021, 11. Réf. HAL: hal-03292120

Marotte L., Capitao M., Deleine C., Beauvais T., Cadiou G., Perrin J., Chérel M., Scotet E., Guilloux Y., Bruchertseifer F., Morgenstern A., Jarry A., Gaschet J., Labarrière N., Anti-tumor efficacy of a combination therapy with PD-L1 targeted alpha therapy and adoptive cell transfer of PD-1 deficient melanoma-specific human T-lymphocytes. OncoImmunology., 2021, 10(1):e1940676. Réf. HAL: inserm-03271847

Mutala L. Bilonda, Deleine C., Karakachoff M., Dansette D., Ducoin K., Oger R., Rousseau O., Podevin J., Duchalais E., Fourquier P., Thomas W. El Alami, Gourraud P.A., Bennouna J., Brochier C., Gervois N., Bossard C., Jarry A., The Caspase-1/IL-18 Axis of the Inflammasome in Tumor Cells: A Modulator of the Th1/Tc1 Response of Tumor-Infiltrating T Lymphocytes in Colorectal Cancer. Cancers., 2021, 13(2):189. Réf. HAL: inserm-03287920

Pochard C., Gonzales J., Bessard A., Mahe M. M, Bourreille A., Cenac N., Jarry A., Coron E., Podevin J., Meurette G., Neunlist M., Rolli-Derkinderen M., PGI 2 Inhibits Intestinal Epithelial Permeability and Apoptosis to Alleviate Colitis. Cellular and Molecular Gastroenterology and Hepatology., 2021, S2352-345X(21)00090-4. Réf. HAL: inserm-03287962

Equipe 04

Briolay T., Petithomme T., Fouet M., Nguyen-Pham N., Blanquart C., Boisgerault N., Delivery of cancer therapies by synthetic and bio-inspired nanovectors. Molecular Cancer., 2021, 20(1):55. Réf. HAL: inserm-03187595

Sun S., Frontini F., Qi W., Hariharan A., Ronner M., Wipplinger M., Blanquart C., Rehrauer H., Fonteneau J.F., Felley-Bosco E., Endogenous Retrovirus expression activates type-I interferon signaling in an experimental mouse model of mesothelioma development. Cancer Letters., 2021, 507:26 – 38. Réf. HAL: inserm-03171655

Tournier P., Guicheux J., Paré A., Maltezeanu A., Blondy T., Veziers J., Vignes C., André M., Lesoeur J., Barbeito A. G., Bardonnet R., Blanquart C., Corre P., Geoffroy V., Weiss P., Gaudin A., A partially demineralized allogeneic bone graft: in vitro osteogenic potential and preclinical evaluation in two different intramembranous bone healing models. Scientific Reports., 2021, 11(1):4907. Réf. HAL: inserm-03157874

Lavy M., Gauttier V., Poirier N., Barillé-Nion S. C, Blanquart C., Specialized Pro-Resolving Mediators Mitigate Cancer-Related Inflammation: Role of Tumor-Associated Macrophages and Therapeutic Opportunities. Frontiers in Immunology., 2021, 12:702785. Réf. HAL: inserm-03319344

Equipe 05

Le Pendu J., Breiman A., Deleers M., El Kenz H., Ruvoën N., COVID-19 et groupes sanguins ABO : Où en est-on ? médecine/sciences., 2021, 37(6-7):565-568. Réf. HAL: hal-03273125

Lefebvre M., Vignier N., Pitard B., Botelho-Nevers E., Cohen R., Epaulard O., Covid-19 vaccines: frequently asked questions and updated answers. Infectious Diseases Now., 2021, Online ahead of print. Réf. HAL: inserm-03171616

Pendu J. Le, Breiman A., Rocher J., Dion M., Ruvoën-Clouet N., ABO Blood Types and COVID-19: Spurious, Anecdotal, or Truly Important Relationships? A Reasoned Review of Available Data. Viruses., 2021, 13(2):160. Réf. HAL: inserm-03122495

Equipe 06

Douillet D., Caillaud A., Riou J., Miroux P., Thibaud E., Noizet M., Oberlin M., Léger M., Mahieu R., Riquin E., Javaudin F., Morin F., Moumneh T., Savary D., Roy P.M., Hugli O., Assessment of physicians’ resilience level during the COVID-19 pandemic. Translational Psychiatry., 2021, 11:283. Réf. HAL: hal-03253675

Douillet D., Penaloza A., Mahieu R., Morin F., Chauvin A., Gennai S., Schotte T., Montassier E., Thiebaud P.C., Ghuysen A., Dall’acqua D., Benhammouda K., Bissokele P., Violeau M., Joly L.M., Andrianjafy H., Soulie C., Savary D., Riou J., Roy P.M., Outpatient Management of Patients With COVID-19: Multicenter Prospective Validation of the Hospitalization or Outpatient Management of Patients With SARS-CoV-2 Infection Rule to Discharge Patients Safely. Chest., 2021,. Réf. HAL: hal-03253811

Robbe-Saule M., Foulon M., Poncin I., Esnault L., Varet H., Legendre R., Besnard A., Grzegorzewicz A. E, Jackson M., Canaan S., Marsollier L., Marion E., Transcriptional adaptation of Mycobacterium ulcerans in an original mouse model: New insights into the regulation of mycolactone. Virulence., 2021, 12(1):1438 – 1451. Réf. HAL: pasteur-03257175

Equipe 07

Brilland B., Bach-Bunner M., Gomes C.N., Larochette V., Foucher E., Plaisance M., Saulnier P., Costedoat-Chalumeau N., Ghillani P., Belizna C., Delneste Y., Augusto J.F., Jeannin P., Serum Interleukin-26 Is a New Biomarker for Disease Activity Assessment in Systemic Lupus Erythematosus. Frontiers in Immunology., 2021, 12:663192. Réf. HAL: inserm-03267806

Brilland B., Vinatier E., Subra J.F., Jeannin P., Augusto J.F., Delneste Y., Anti-Pentraxin Antibodies in Autoimmune Diseases: Bystanders or Pathophysiological Actors? Frontiers in Immunology., 2021, Online ahead of print. Réf. HAL: inserm-03142425

Jourdain P., Brilland B., Medhioub O., Caron J., Samoreau C., Djema A., Gansey R., Coindre J.P., Cousin M., Garnier A.S., Henry N., Wacrenier S., Riou J., Piccoli G.B., Augusto J.F., Incidence and Temporal Trend in Risk Factors of Severe Infections in ANCA-Glomerulonephritis Patients. Kidney International Reports., 2021, 6(4):1161-1165. Réf. HAL: inserm-03267787

Lacombe V., Nunes Gomes C., Robin J., Thépot S., François S., Cottin L., Ugo V., Dieu X., Abgueguen P., Daniel V., Giltat A., Hunault M., Riou J., Orvain C., Schmidt A., Risk of infection according to the gamma globulin level in the 100 days following allogeneic stem cell transplantations. European Journal of Haematology., 2021, Online ahead of print. Réf. HAL: inserm-03315916

Luque Paz D., Riou J., Verger E., Cassinat B., Chauveau A., Ianotto J.C., Dupriez B., Boyer F., Renard M., Mansier O., Murati A., Rey J., Etienne G., Mansat-De Mas V., Tavitian S., Nibourel O., Girault S., Le Bris Y., Girodon F., Ranta D., Chomel J.C., Cony-Makhoul P., Sujobert P., Robles M., Ben Abdelali R., Kosmider O., Cottin L., Roy L., Sloma I., Vacheret F., Wemeau M., Mossuz P., Slama B., Cussac V., Denis G., Walter-Petrich A., Burroni B., Jézéquel N., Giraudier S., Lippert E., Socié G., Kiladjian J.J., Ugo V., Genomic analysis of primary and secondary myelofibrosis redefines the prognostic impact of ASXL1 mutations: a FIM study. Blood Advances., 2021, 5:1442 – 1451. Réf. HAL: inserm-03187575

Mabilleau G., Delneste Y., Papon N., Predicting Bone Regeneration with a Simple Blood Test. Trends in Molecular Medicine., 2021,. Réf. HAL: hal-03208763

Moulin C., Guillemin F., Remen T., Bouclet F., Hergalant S., Quinquenel A., Dartigeas C., Tausch E., Lazarian G., Blanchet O., Lomazzi S., Chapiro E., Schneider C., Nguyen‐khac F., Davi F., Hunault M., Tomowiak C., Roos‐weil D., Siebert R., Thieblemont C., Cymbalista F., Laribi K., Béné M., Stilgenbauer S., Guièze R., Feugier P., Broséus J., Clinical, biological, and molecular genetic features of Richter syndrome and prognostic significance: a study of the French Innovative Leukemia Organization. American Journal of Hematology., 2021,. Réf. HAL: hal-03238759

Prat M., Salon M., Allain T., Dubreuil O., Noël G., Preisser L., Jean B., Cassard L., Lemée F., Tabah-Fish I., Pipy B., Jeannin P., Prost J.F., Barret J.M., Coste A., Murlentamab, a Low Fucosylated Anti-Müllerian Hormone Type II Receptor (AMHRII) Antibody, Exhibits Anti-Tumor Activity through Tumor-Associated Macrophage Reprogrammation and T Cell Activation. Cancers., 2021, 13(8):1845. Réf. HAL: inserm-03215770

Staerck C., Yaakoub H., Vandeputte P., Tabiasco J., Godon C., Gastebois A., Giraud S., Guillemette T., Calenda A., Delneste Y., Fleury M., Bouchara J.P., The Glycosylphosphatidylinositol-Anchored Superoxide Dismutase of Scedosporium apiospermum Protects the Conidia from Oxidative Stress. Journal of Fungi., 2021, 7:575. Réf. HAL: inserm-03309902

Sureau L., Orvain C., Ianotto J.C., Ugo V., Kiladjian J.J., Luque Paz D., Riou J., Efficacy and tolerability of Janus kinase inhibitors in myelofibrosis: a systematic review and network meta-analysis. Blood Cancer Journal., 2021, 11(7):135. Réf. HAL: inserm-03315915

Wicker‐Planquart C., Tacnet‐Delorme P., Preisser L., Dufour S., Delneste Y., Housset D., Frachet P., Thielens N. M., Insights into the ligand binding specificity of SREC‐II (scavenger receptor expressed by endothelial cells). FEBS Open Bio., 2021, Online ahead of print. Réf. HAL: inserm-03315913

Lemoine S., Renard M., Bouvier A., Orvain C., Giltat A., Cottin L., Blanchet O., Hunault-Berger M., Ugo V., Luque Paz D., No detection of atypical one-base deletion of CALR exon 9 with fragment analysis: A molecular trap to avoid. Blood Cells, Molecules and Diseases., 2021, 90:102589. Réf. HAL: inserm-03315920

Equipe 08

Colombié M., Jézéquel P., Rubeaux M., Frenel J.S., Bigot F., Seegers V., Campone M., The EPICURE study: a pilot prospective cohort study of heterogeneous and massive data integration in metastatic breast cancer patients. BMC Cancer., 2021, 21(1):333. Réf. HAL: inserm-03218545

Duclos M., Prigent C., Le Borgne R., Guen V.J., Three-Dimensional Imaging of Organoids to Study Primary Ciliogenesis During ex vivo Organogenesis. Journal of visualized experiments : JoVE., 2021,(171). Réf. HAL: hal-03260699

Tea I., De Luca A., Schiphorst A.M., Grand M., Barillé-Nion S., Mirallié E., Drui D., Krempf M., Hankard R., Tcherkez G., Stable Isotope Abundance and Fractionation in Human Diseases. Metabolites., 2021, 11(6):370. Réf. HAL: hal-03313301

Equipe 09

Cadé M., Munoz-Garcia J., Babuty A., Marc Fouassier M., Heymann M.F., Monahan P. E, Heymann D., FVIII at the crossroad of coagulation, bone and immune biology: emerging evidence biological activities beyond hemostasis : Factor VIIIbeyond hemostasis. Drug Discovery Today., 2021, S1359-6446(21)00321-4. Réf. HAL: inserm-03298299

Clézardin P., Coleman R., Puppo M., Ottewell P., Bonnelye E. E, Paycha F., Confavreux C., Holen I., Bone Metastasis: Mechanisms, Therapies and Biomarkers. Physiological Reviews., 2021,. Réf. HAL: hal-03102895

Guérard A., Laurent V., Fromont G., Estève D., Gilhodes J., Bonnelye E. E, Gonidec S.L., Valet P., Malavaud B., Reina N., Attané C., Muller C., The Chemokine Receptor CCR3 Is Potentially Involved in the Homing of Prostate Cancer Cells to Bone: Implication of Bone-Marrow Adipocytes. International Journal of Molecular Sciences., 2021, 22(4):1994. Réf. HAL: hal-03146140

Jakobczyk H., Debaize L., Soubise B., Avner S., Rouger-Gaudichon J., Commet S., Jiang Y., Serandour A.A., Rio A.G., Carroll J., Wichmann C., Lie-A-Ling M., Lacaud G., Corcos L., Salbert G., Galibert M.D., Gandemer V., Troadec M.B., Reduction of RUNX1 transcription factor activity by a CBFA2T3-mimicking peptide: application to B cell precursor acute lymphoblastic leukemia. Journal of Hematology and Oncology., 2021, 14:47. Réf. HAL: hal-03215796

Lalier L., Mignard V., Joalland M.P., Lanoé D., Cartron P.F., Manon S., Vallette F. M, TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis. Cell Death and Disease., 2021, 12(2):182. Réf. HAL: inserm-03145368

Massy E., Rousseau J.C., Gueye M., Bonnelye E., Brevet M., Chambard L., Duruisseaux M., Borel O., Roger C., Guelminger R., Pialat J.B., Gineyts E., Bouazza L., Millet M., Maury J.M., Clézardin P., Girard N., Confavreux C. B, Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma. Journal of Bone Oncology., 2021, 29:100364. Réf. HAL: hal-03263846

Muñoz-Garcia J., Cochonneau D., Télétchéa S., Moranton E., Lanoe D., Brion R., Lézot F., Heymann M.F., Heymann D., The twin cytokines interleukin-34 and CSF-1: masterful conductors of macrophage homeostasis. Theranostics., 2021, 11(4):1568-1593. Réf. HAL: inserm-03298306

Muñoz-Garcia J., Jubelin C., Loussouarn A., Goumard M., Griscom L., Renodon-Cornière A., Heymann M.F., Heymann D., In vitro three-dimensional cell cultures for bone sarcomas. Journal of Bone Oncology., 2021, 30:100379. Réf. HAL: inserm-03298212

Olivier C., Oliver L., Lalier L., Vallette F. M., Drug Resistance in Glioblastoma: The Two Faces of Oxidative Stress. Frontiers in Molecular Neuroscience., 2021,. Réf. HAL: inserm-03136960

Pantano F., Croset M., Driouch K., Bednarz-Knoll N., Iuliani M., Ribelli G., Bonnelye E. E, Wikman H., Geraci S., Bonin F., Simonetti S., Vincenzi B., Hong S.S., Sousa S., Pantel K., Tonini G., Santini D., Clézardin P., Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions. Oncogene., 2021,. Réf. HAL: hal-03104932

Terrié E., Déliot N., Benzidane Y., Harnois T., Cousin L., Bois P., Oliver L., Arnault P., Vallette F., Constantin B., Coronas V., Store-Operated Calcium Channels Control Proliferation and Self-Renewal of Cancer Stem Cells from Glioblastoma. Cancers., 2021, 13(14):3428. Réf. HAL: inserm-03287913

Yoshioka H., Okita S., Nakano M., Minamizaki T., Nubukiyo A., Sotomaru Y., Bonnelye E., Kozai K., Tanimoto K., Aubin J. E, Yoshiko Y., Single‐Cell RNA ‐Sequencing Reveals the Breadth of Osteoblast Heterogeneity. JBMR Plus., 2021, 5(6). Réf. HAL: hal-03263878

Equipe 10

Damien Luque Paz, Jeremie Riou, Emmanuelle Verger, Bruno Cassinat, Aurelie Chauveau, Jean-Christophe Ianotto, Brigitte Dupriez, Francoise Boyer, Maxime Renard, Olivier Mansier, Anne Murati, Jerôme Rey, Gabriel Etienne, Veronique Mansat-De Mas, Suzanne Tavitian, Olivier Nibourel, Stephane Girault, Yannick Le Bris, Francois Girodon, Dana Ranta, Jean-Claude Chomel, Pascale Cony-Makhoul, Pierre Sujobert, Margot Robles, Raouf Ben Abdelali, Olivier Kosmider, Laurane Cottin, Lydia Roy, Ivan Sloma, Fabienne Vacheret, Mathieu Wemeau, Pascal Mossuz, Borhane Slama, Vincent Cussac, Guillaume Denis, Anouk Walter-Petrich, Barbara Burroni, Nathalie Jezequel, Stephane Giraudier, Eric Lippert, Gerard Socie, Jean-Jacques Kiladjian, and Valerie Ugo. Genomic analysis of primary and secondary myelo brosis rede nes the prognostic impact of ASXL1 mutations: a FIM study. Blood Advances, 2021. inserm-03187575.

David Chiron. Commentary on Rodrigues et al : derstanding of B-cell lymphomas aggressiveness. Towards ecosystem integration for a better understanding of B-cell lymphomas aggressiveness. British Journal of Haematology, 2021. inserm-03128392.

Benoit Tessoulin, David Chiron, Catherine Thieblemont, Lucie Oberic, Kamal Bouadballah, Emmanuel Gyan, Gandhi Damaj, Vincent Ribrag, Remy Gressin, Pierre Feugier, Olivier Casasnovas, Hacene Zerazhi, Francois Lemonnier, Herve Maisonneuve, Clementine Joubert, Eric Van Den Neste, Thierry Lamy, Herve Tilly, Anne Moreau, Olivier Hermine, and Steven Le Gouill. Oxaliplatin before autologous transplantation in combination with high-dose cytarabine and rituximab provides longer disease control than cisplatin or carboplatin in patients with mantle-cell lymphoma: results from the LyMA prospective trial. Bone Marrow Transplantation. hal-03203334.

Equipe 12

Pouliquen D. L, Kopecka J., Malignant Mesothelioma. Cancers., 2021, 13:3447. Réf. HAL: inserm-03287907

Equipe 13

Ansquer C., Touchefeu Y., Faivre-Chauvet A., Leux C., Le Bras M., Régenet N., Fleury V., Maucherat B., Senellart H., Guyetant S., Carlier T., Scotet-Cérato E., Rauscher A., Frampas E., Kraeber-Bodéré F., Head-to-Head Comparison of 18F-DOPA PET/CT and 68Ga-DOTANOC PET/CT in Patients With Midgut Neuroendocrine Tumors. Clinical Nuclear Medicine., 2021, 46(3):181-186. Réf. HAL: hal-03115018

Berdal M., Gouard S., Eychenne R., Marionneau-Lambot S., Croyal M., Faivre-Chauvet A., Chérel M., Gaschet J., Gestin J.F., Guérard F., Investigation on the reactivity of nucleophilic radiohalogens with arylboronic acids in water: access to an efficient single-step method for the radioiodination and astatination of antibodies. Chemical Science ., 2021, 12(4):1458-1468. Réf. HAL: inserm-03024891

Chevalme Y.M., Boudali L., Gauthé M., Rousseau C., Skanjeti A., Merlin C., Robin P., Giraudet A.L., Janier M., Talbot J.N., Survey by the French Medicine Agency (ANSM) of the imaging protocol, detection rate, and safety of 68Ga-PSMA-11 PET/CT in the biochemical recurrence of prostate cancer in case of negative or equivocal 18F-fluorocholine PET/CT: 1084 examinations. European Journal of Nuclear Medicine and Molecular Imaging., 2021, Online ahead of print. Réf. HAL: inserm-03109828

Delage J. Anna, Faivre-Chauvet A., Barbet J., Fierle J. Katrin, Schaefer N., Coukos G., Viertl D., Dunn S. Mark, Gnesin S., Prior J. O, Impact of DOTA Conjugation on Pharmacokinetics and Immunoreactivity of [177Lu]Lu-1C1m-Fc, an Anti TEM-1 Fusion Protein Antibody in a TEM-1 Positive Tumor Mouse Model. Pharmaceutics., 2021, 13(96):Online ahead of print. Réf. HAL: inserm-03109836

Eychenne R., Chérel M., Haddad F., Guérard F., Gestin J.F., Overview of the Most Promising Radionuclides for Targeted Alpha Therapy: The “Hopeful Eight”. Pharmaceutics., 2021, 13(6):906. Réf. HAL: inserm-03292397

Guérard F., Maingueneau C., Liu L., Eychenne R., Gestin J.F., Montavon G. F, Galland N., Advances in the chemistry of astatine and implications for the development of radiopharmaceuticals. Accounts of Chemical Research., 2021,. Réf. HAL: inserm-03290202

Knighton R. C, Troadec T., Mazan V., Le Saëc P., Marionneau-Lambot S., Le Bihan T., Saffon‐merceron N., Le Bris N., Chérel M., Faivre-Chauvet A., Elhabiri M., Charbonnière L. J, Tripier R., Cyclam-Based Chelators Bearing Phosphonated Pyridine Pendants for 64 Cu-PET Imaging: Synthesis, Physicochemical Studies, Radiolabeling, and Bioimaging. Inorganic Chemistry., 2021, 60(4):2634–2648. Réf. HAL: hal-03123032

Marotte L., Capitao M., Deleine C., Beauvais T., Cadiou G., Perrin J., Chérel M., Scotet E., Guilloux Y., Bruchertseifer F., Morgenstern A., Jarry A., Gaschet J., Labarrière N., Anti-tumor efficacy of a combination therapy with PD-L1 targeted alpha therapy and adoptive cell transfer of PD-1 deficient melanoma-specific human T-lymphocytes. OncoImmunology., 2021, 10(1):e1940676. Réf. HAL: inserm-03271847

Mazza M., Alliot C., Sinquin C., Colliec-Jouault S., Reiller P. E, Huclier-Markai S., Marine Exopolysaccharide Complexed With Scandium Aimed as Theranostic Agents. Molecules., 2021, 26(4):1143. Réf. HAL: hal-03187695

Proisy M., Vivier P.H., Morel B., Bruneau B., Sembely-Taveau C., Vacheresse S., Devillers A., Lecloirec J., Bodet-Milin C., Dubois M., Hamonic S., Bajeux E., Ganivet A., Adamsbaum C., Treguier C., Whole-body MR imaging in suspected physical child abuse: comparison with skeletal survey and bone scintigraphy findings from the PEDIMA prospective multicentre study. European Radiology., 2021, Online ahead of print. Réf. HAL: inserm-03214574

Equipe 14

Bahri M., Kailayangiri S., Vermeulen S., Galopin N., Rossig C., Paris F., Fougeray S., Birklé S., SIRPα-specific monoclonal antibody enables antibody-dependent phagocytosis of neuroblastoma cells. Cancer Immunology, Immunotherapy., 2021, Online ahead of print. Réf. HAL: inserm-03240786

Sosa-Marrero C., De Crevoisier R., Hernandez A., Fontaine P., Rioux-Leclercq N., Mathieu R., Fautrel A., Paris F., Acosta O., Towards a reduced in silico model predicting biochemical recurrence after radiotherapy in prostate cancer. IEEE Transactions on Biomedical Engineering., 2021, 1-1. Réf. HAL: inserm-03137032

Equipe 15

Ghoroghi S., Mary B., Larnicol A., Asokan N., Klein A., Osmani N., Busnelli I., Delalande F., Paul N., Halary S., Gros F., Fouillen L., Haeberle A.M., Royer C., Spiegelhalter C., André-Grégoire G. M, Mittelheisser V., Detappe A., Murphy K., Timpson P., Carapito R., Blot-Chabaud M., Gavard J., Carapito C., Vitale N., Lefebvre O., Goetz J.G., Hyenne V., Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes. eLife., 2021,(10):e61539. Réf. HAL: inserm-03103515

Huna A., Nawrocki-Raby B., Padilla-Benavides T., Gavard J., Coscoy S., Bernard D., Boissan M., Loss of the Metastasis Suppressor NME1, But Not of Its Highly Related Isoform NME2, Induces a Hybrid Epithelial–Mesenchymal State in Cancer Cells. International Journal of Molecular Sciences., 2021, 22(7):3718. Réf. HAL: inserm-03191241

Rosińska S., Gavard J., Tumor Vessels Fuel the Fire in Glioblastoma. International Journal of Molecular Sciences., 2021, 22(12):6514. Réf. HAL: inserm-03265068

Thys A., Trillet K., Rosinska S., Gayraud A., Douanne T., Danger Y., Renaud C.C.N., Antigny L., Lavigne R., Pineau C., Com E., Vérité F., Gavard J., Bidère N., Serine 165 phosphorylation of SHARPIN regulates the activation of NF-κB. iScience., 2021, 24(1):101939. Réf. HAL: hal-03099208

Equipe 16

Jean Harb, Nicolas Mennesson, Cassandra Lepetit, Maeva Fourny, Margaux Louvois, Adrien Bosseboeuf, Sophie Allain-Maillet, Olivier Decaux, Caroline Moreau, Anne Tallet, Eric Piver, Philippe Moreau, Valery Salle, Edith Bigot-Corbel, and Sylvie Hermouet. Comparison of Monoclonal Gam-mopathies Linked to Poliovirus or Coxsackievirus vs. Other Infectious Pathogens. Cells, 2021. inserm-03148367.

Equipe 17

Melanie Pages, Emmanuelle Uro-Coste, Carole Colin, David Meyronet, Guillaume Gauchotte, Claude-Alain Maurage, Audrey Rousseau, Catherine Godfraind, Karima Mokhtari, Karen Silva, Dominique Figarella-Branger, and Pascale Varlet. The Implementation of DNA Methylation Pro ling into a Multistep Diagnostic Process in Pediatric Neuropathology: A 2-Year Real-World Experience by the French Neuropathology Network. Cancers, 2021. hal-03190280.

Clement Toullec, Jean Le Bideau, Valerie Geoffroy, Boris Halgand, Nela Buchtova, Rodolfo Molina-Pena, Emmanuel Garcion, Sylvie Avril, Laurence Sindji, Admire Dube, Frank Boury, and Christine Jerome. Curdlan-Chitosan Electrospun Fibers as Potential Scaffolds for Bone Regeneration. Polymers, 2021. inserm-03137953.

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