Sélection et réactivité des cellules iNKT humaines/Développement d’anticorps monoclonaux humains

PUBLICATIONS

Legoux F, Gautreau L, Hesnard L, Leger A, Moyon M, Devilder MC, Bonneville M, Saulquin X. Characterization of the human CD4(+) T-cell repertoire specific for major histocompatibility class I-restricted antigens. Eur J Immunol. 2013

Hesnard L, Legoux F, Gautreau L, Moyon M, Baron O, Devilder MC, Bonneville M, Saulquin X. 2016. Role of the MHC restriction during maturation of antigen-specific human T cells in the thymus. Eur J Immunol. 2016

Ouisse LH, Gautreau-Rolland L, Devilder MC, Osborn M, Moyon M, Visentin J, Halary F, Bruggemann M, Buelow R, Anegon I, Saulquin X. Antigen-specific single B cell sorting and expression-cloning from immunoglobulin humanized rats: a rapid and versatile method for the generation of high affinity and discriminative human monoclonal antibodies. BMC Biotechnol. 2017

Devilder MC., Moyon M., Saulquin X., Gautreau-Rolland L. Generation of Discriminative Human Monoclonal Antibodies from Rare Antigen-specific B Cells Circulating in Blood. Journal of visualized experiments : JoVE. 2018

Devilder MC, Moyon M, Gautreau-Rolland L, Navet B, Perroteau J, Delbos F, Gesnel MC, Breathnach R, Saulquin X. Ex vivo evolution of human antibodies by CRISPR-X: from a naive B cell repertoire to affinity matured antibodies. BMC Biotechnol. 2019