Lisa Nocquet, Philippe Juin, and Frederique Souaze. Mitochondria at Center of Exchanges be-tween Cancer Cells and Cancer-Associated Fibroblasts during Tumor Progression. Cancers, 2020. inserm-02978374.
Amandine Billaud, Louise-Marie Chevalier, Mario Campone, Alain Morel, and Frederic Bigot. L’instabilite genomique, parametre limitant l’efficacite des therapies ciblees en oncologie. Bulletin du Cancer, 2020. inserm-02978363.
Kristell Oizel, Chendong Yang, Ophelie Renoult, Fabien Gautier, Quyen N Do, Noemie Joalland, Xiaofei Gao, Bookyung Ko, Francois Vallette, Woo-Ping Ge, Francois Paris, Ralph J DeBerardinis, and Claire Pecqueur. Glutamine uptake and utilization of human mesenchymal glioblastoma in orthotopic mouse model. Cancer and Metabolism, 2020. inserm-03013555.
Pascal Jezequel, Anne Patsouris, Catherine Guette, Philippe Juin, and Mario Campone. RE: Immune checkpoint pro les in luminal B breast cancer (Alliance). Journal of the National Cancer Institute, 2020. inserm-02524151.
Elie Dagher, Laura Simbault, Jerôme Abadie, Delphine Loussouarn, Mario Campone, and Frederique Nguyen. Identification of an immune-suppressed subtype of feline triple-negative basal-like invasive mammary carcinomas, spontaneous models of breast cancer. Tumor Biology, 2020. inserm-02484624.
Floriane Etienne, Maxime Berthaud, Frederique Nguyen, Karine Bernardeau, Catherine Maurel, Caroline Bodet-Milin, Maya Diab, Jerôme Abadie, Valerie Gouilleux-Gruart, Aurelien Vidal, Mickael Bourgeois, Nicolas Chouin, Catherine Ibisch, and Francois Davodeau. SPECT-CT Imaging of Dog Spontaneous Diffuse Large B-Cell Lymphoma Targeting CD22 for the Implementation of a Relevant Preclinical Model for Human. Frontiers in Oncology, 2020. inserm-02512859.
Carolane Seiller, Sophie Maiga, Cyrille Touzeau, Celine Bellanger, Charlotte Kervoelen, Geraldine Descamps, Laurent Maillet, Philippe Moreau, Catherine Pellat-Deceunynck, Patricia Gomez-Bougie, and Martine Amiot. Dual targeting of BCL2 and MCL1 rescues myeloma cells resistant to BCL2 and MCL1 inhibitors associated with the formation of BAX/ BAK hetero-complexes. Cell Death and Disease, 2020. inserm-02563554.
Steven Lohard, Nathalie Bourgeois, Laurent A Maillet, Fabien P Gautier, Aurelie Fetiveau, Hamza Lasla, Frederique Nguyen, Celine Vuillier, Alison Dumont, Agnes Moreau-Aubry, Morgane Frapin, Laurent David, Delphine Loussouarn, Olivier Kerdraon, Mario Campone, Pascal Jezequel, Philippe Juin, and Sophie Barille-Nion. STING-dependent paracriny shapes apoptotic priming of breast tumors in response to anti-mitotic treatment. Nature Communications, 2020. inserm-02448103.
Cindy Pensec, Florence Gillaizeau, Dominique Guenot, Anne Bessard, Thomas Carton, Sebastien Leuillet, Mario Campone, Michel Neunlist, Herv Blottiere, and Francoise Le Vacon. Impact of pemetrexed chemotherapy on the gut microbiota and intestinal in ammation of patient-lung-derived tumor xenograft (PDX) mouse models. Scientific Reports, 2020. hal-03098267.
Lea Paolini, Clement Adam, Celine Beauvillain, Laurence Preisser, Simon Blanchard, Pascale Pignon, Valerie Seegers, Louise-Marie Chevalier, Mario Campone, Romuald Wernert, Veronique Verriele, Pedro Raro, Norbert Ifrah, Vincent Lavoue, Philippe Descamps, Alain Morel, Veronique Catros, Guillaume Tcherkez, Guy Lenaers, Cinzia Bocca, Judith Kouassi Nzoughet, Vincent Procaccio, Yves Delneste, and Pascale Jeannin. Lactic acidosis together with GM-CSF and M-CSF induces human macrophages toward an in ammatory pro-tumor phenotype. Cancer Immunology Research, 2020. hal-02442525.
Appala Venkata Ramana Murthy, Vennu Narendar, Nangunoori Sampath Kumar, Pasula Aparna, Anagani Kanaka Durga Bhavani, Fabien Gautier, Sophie Barillé-Nion, Philippe Juin, Paul Mosset, René Grée, Nicolas Levoin. Targeting PUMA/Bcl-xL interaction by new specific compounds to unleash apoptotic process in cancer cells. European Journal of Medicinal Chemistry. 334-347. hal-01937242
Elie Dagher, Jérôme Abadie, Delphine Loussouarn, Dominique Fanuel, Mario Campone, Frédérique Nguyen. Bcl-2 expression and prognostic significance in feline invasive mammary carcinomas: a retrospective observational study. BMC Veterinary Research. 25. inserm-01991065
Kevin Louault, Thomas Bonneaud, Céline Séveno, Patricia Gomez-Bougie, Frédérique Nguyen, Fabien Gautier, Nathalie Bourgeois, Delphine Loussouarn, Olivier Kerdraon, Sophie Barillé-Nion, Pascal Jézéquel, Mario Campone, Martine Amiot, Philippe Juin, Frédérique Souazé. Interactions between cancer-associated fibroblasts and tumor cells promote MCL-1 dependency in estrogen receptor-positive breast cancers. Oncogene. Epub ahead of print. inserm-01991165
Jordan Guillon, Coralie Petit, Marie Moreau, Bertrand Toutain, Cécile Henry, Henry Roché, Nathalie Bonichon-Lamichhane, Jean Salmon, Jérôme Lemonnier, Mario Campone, Veronique Verriele, Eric Lelièvre, Catherine Guette, Olivier Coqueret. Regulation of senescence escape by TSP1 and CD47 following chemotherapy treatment. Cell Death and Disease. inserm-02055140
Pascal Jézéquel, Olivier Kerdraon, Hubert Hondermarck, Catherine Guérin-Charbonnel, Hamza Lasla, Wilfried Gouraud, Jean-Luc Canon, Andrea Gombos, Florence Dalenc, Suzette Delaloge, Jérôme Lemonnier, Delphine Loussouarn, Veronique Verriele, Mario Campone. Identification of three subtypes of triple-negative breast cancer with potential therapeutic implications. Breast Cancer Research. 65. inserm-02140196
Elie Dagher, Jérôme Abadie, Delphine Loussouarn, Mario Campone, Frédérique Nguyen. Feline Invasive Mammary Carcinomas: Prognostic Value of Histological Grading. Veterinary Pathology. inserm-02167919
Isabelle Valo, Pédro Raro, Alice Boissard, Amine Maarouf, Pascal Jézéquel, Veronique Verriele, Mario Campone, Olivier Coqueret, Catherine Guette. OLFM4 Expression in Ductal Carcinoma In Situ and in Invasive Breast Cancer Cohorts by a SWATH‐Based Proteomic Approach. Proteomics. e1800446. inserm-02281345
Pascal Jézéquel, Catherine Guette, Hamza Lasla, Wilfried Gouraud, Alice Boissard, Catherine Guérin-Charbonnel, Mario Campone. iTRAQ‐Based Quantitative Proteomic Analysis Strengthens Transcriptomic Subtyping of Triple‐Negative Breast Cancer Tumors. Proteomics. 1800484. inserm-02281393
Florian Chocteau, Jérôme Abadie, Delphine Loussouarn, Frédérique Nguyen. Proposal for a Histological Staging System of Mammary Carcinomas in Dogs and Cats. Part 1: Canine Mammary Carcinomas. Frontiers in Veterinary Science (2019). inserm-02383821
Florian Chocteau, Marie-Mélanie Boulay, Fanny Besnard, Germain Valeau, Delphine Loussouarn, Frédérique Nguyen. Proposal for a Histological Staging System of Mammary Carcinomas in Dogs and Cats. Part 2: Feline Mammary Carcinomas. Frontiers in Veterinary Science (2019). inserm-02383102
Pierre Avril, Luciano Vidal, Sophie Barille-Nion, Louis-Romée Le Nail, Françoise Rédini, Pierre Layrolle, Michelle Pinault, Stéphane Chevalier, Pierre Perrot, Valérie Trichet. Epinephrine Infiltration of Adipose Tissue Impacts MCF7 Breast Cancer Cells and Total Lipid Content. International Journal of Molecular Sciences Article (2019). inserm-02383856
Jennifer Allègre, Jessy Cartier, Valérie Glorian, Droin Nathalie, Baptiste Dumetier, Cémile Kayaci, Jean Berthelet, Simon Gemble, Céline Vuillier, Laurent Maillet, Carmen Garrido, Laurence Dubrez. E2F1 binds to the peptide-binding groove within the BIR3 domain of cIAP1 and requires cIAP1 for chromatin binding. PLoS ONE. (2018) e0206253. hal-01923499
Pascal Jézéquel, Mario Campone. Comment on “How the evolution of multicellularity set the stage for cancer”. British Journal of Cancer. (2018) Epub ahead of print. inserm-01823385
Lorenzo Galluzzi, Ilio Vitale, Stuart A. Aaronson, John M. Abrams, Dieter Adam, Patrizia Agostinis, Emad S. Alnemri, Lucia Altucci, Ivano Amelio, David W. Andrews, Margherita Annicchiarico-Petruzzelli, Alexey V. Antonov, Eli Arama, Eric H. Baehrecke, Nickolai A. Barlev, Nicolas G. Bazan, Francesca Bernassola, Mathieu J. M. Bertrand, Katiuscia Bianchi, Mikhail V. Blagosklonny, Klas Blomgren, Christoph Borner, Patricia Boya, Catherine Brenner, Michelangelo Campanella, Eleonora Candi, Didac Carmona-Gutierrez, Francesco Cecconi, Francis K.-M. Chan, Navdeep S. Chandel, Emily H. Cheng, Jerry E. Chipuk, John A. Cidlowski, Aaron Ciechanover, Gerald M. Cohen, Marcus Conrad, Juan R. Cubillos-Ruiz, Peter E. Czabotar, Vincenzo D Angiolella, Ted M. Dawson, Valina L. Dawson, Vincenzo De Laurenzi, Ruggero De Maria, Klaus-Michael Debatin, Ralph J. DeBerardinis, Mohanish Deshmukh, Nicola Di Daniele, Francesco Di Virgilio, Vishva M. Dixit, Scott J. Dixon, Colin S. Duckett, Brian D. Dynlacht, Wafik S. El-Deiry, John W. Elrod, Gian Maria Fimia, Simone Fulda, Ana J. García-Sáez, Abhishek D. Garg, Carmen Garrido, Evripidis Gavathiotis, Pierre Golstein, Eyal Gottlieb, Douglas R. Green, Lloyd A. Greene, Hinrich Gronemeyer, Atan Gross, Gyorgy Hajnoczky, J. Marie Hardwick, Isaac S. Harris, Michael O. Hengartner, Claudio Hetz, Hidenori Ichijo, Marja Jäättelä, Bertrand Joseph, Philipp J. Jost, Philippe P. Juin, William J. Kaiser, Michael Karin, Thomas Kaufmann, Oliver Kepp, Adi Kimchi, Richard N. Kitsis, Daniel J. Klionsky, Richard A. Knight, Sharad Kumar, Sam W. Lee, John J. Lemasters, Beth Levine, Andreas Linkermann, Stuart A. Lipton, Richard A. Lockshin, Carlos López-Otín, Scott W. Lowe, Tom Luedde, Enrico Lugli, Marion MacFarlane, Frank Madeo, Michal Malewicz, Walter Malorni, Gwenola Manic, Jean-Christophe Marine, Seamus J. Martin, Jean-Claude Martinou, Jan Paul Medema, Patrick Mehlen, Pascal Meier, Sonia Melino, Edward A. Miao, Jeffery D. Molkentin, Ute M. Moll, Cristina Muñoz-Pinedo, Shigekazu Nagata, Gabriel Nuñez, Andrew Oberst, Moshe Oren, Michael Overholtzer, Michele Pagano, Theocharis Panaretakis, Manolis Pasparakis, Josef M. Penninger, David M. Pereira, Shazib Pervaiz, Marcus E. Peter, Mauro Piacentini, Paolo Pinton, Jochen H.M. Prehn, Hamsa Puthalakath, Gabriel A. Rabinovich, Markus Rehm, Rosario Rizzuto, Cecilia M.P. Rodrigues, David C. Rubinsztein, Thomas Rudel, Kevin M. Ryan, Emre Sayan, Luca Scorrano, Feng Shao, Yufang Shi, John Silke, Hans-Uwe Simon, Antonella Sistigu, Brent R. Stockwell, Andreas Strasser, Gyorgy Szabadkai, Stephen W.G. Tait, Daolin Tang, Nektarios Tavernarakis, Andrew Thorburn, Yoshihide Tsujimoto, Boris Turk, Tom Vanden Berghe, Peter Vandenabeele, Matthew G. Vander Heiden, Andreas Villunger, Herbert W. Virgin, Karen H. Vousden, Domagoj Vucic, Erwin F. Wagner, Henning Walczak, David Wallach, Ying Wang, James A. Wells, Will Wood, Junying Yuan, Zahra Zakeri, Boris Zhivotovsky, Laurence Zitvogel, Gerry Melino, Guido Kroemer. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. (2018) 486–541. hal-01727577
Céline Vuillier, Steven Lohard, Aurélie Fétiveau, Jennifer Allègre, Cémile Kayaci, Louise King, Frédérique Braun, Sophie Barillé-Nion, Fabien Gautier, Laurence Dubrez, Andrew Gilmore, Philippe Juin, Laurent Maillet. E2F1 interacts with BCL‐xL and regulates its subcellular localization dynamics to trigger cell death. EMBO Reports. (2018) 234-243. inserm-01669957
Lazaro Aira, Elodie Villa, Pascal Colosetti, Parvati Gamas, Laurie Signetti, Sandrine Obba, Emma Proics, Fabien Gautier, Beatrice Bailly-Maitre, Arnaud Jacquel, Guillaume Robert, Frédéric Luciano, Philippe Juin, Jean-Ehrland Ricci, Patrick Auberger, Sandrine Marchetti. The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim. Oncogene. (2018) 2122 – 2136. inserm-01814383
Siham Hedir, Marcella De Giorgi, Jade Fogha, Martina De Pascale, Louis-Bastien Weiswald, Emilie Brotin, Bogdan Marekha, Christophe Denoyelle, Camille Denis, Peggy Suzanne, Fabien Gautier, Philippe Juin, Laetitia Ligat, Frédéric Lopez, Ludovic Carlier, Rémi Legay, Ronan Bureau, Sylvain Rault, Laurent Poulain, Jana Sopkova-de Oliveira Santos, Anne-Sophie Voisin-Chiret. Structure-guided design of pyridoclax derivatives based on Noxa / Mcl-1 interaction mode. European Journal of Medicinal Chemistry. (2018) 357-380. inserm-01980723
Marie Robert, Anne Patsouris, Jean-Sébastien Frenel, Carole Gourmelon, Paule Augereau, Mario Campone. Emerging PARP inhibitors for treating breast cancer. Expert Opinion on Emerging Drugs. (2018) 211-221. inserm-01977751
Anne Lok, Géraldine Descamps, Benoit Tessoulin, David Chiron, Marion Eveillard, Catherine Godon, Yannick Le Bris, Astrid Vabret, Céline Bellanger, Laurent Maillet, Sophie Barillé-Nion, Marc Gregoire, Jean-François Fonteneau, Steven Le Gouill, Philippe Moreau, Frederic Tangy, Martine Amiot, Agnès Moreau-Aubry, Catherine Pellat-Deceunynck. p53 regulates CD46 expression and measles virus infection in myeloma cells. Blood Advances. (2018) 3492-3505. inserm-01957487
Sophie De Carné Trécesson, Frédérique Souazé, Agnes Basseville, Anne-Charlotte Bernard, Jessie Pécot, Jonathan Lopez, Margaux Bessou, Kristopher Sarosiek, Anthony Letaï, Sophie Barillé-Nion, Isabelle Valo, Olivier Coqueret, Catherine Guette, Mario Campone, Fabien Gautier, Philippe Juin. BCL-XL directly modulates RAS signalling to favour cancer cell stemnes.. Nature Communications. (2017) 1123. inserm-01628330
Pierre-Samuel Gillardin, Géraldine Descamps, Sophie Maiga, Benoit Tessoulin, Hanane Djamai, Benedetta Lucani, David Chiron, Philippe Moreau, Steven Le Gouill, Martine Amiot, Catherine Pellat-Deceunynck, Agnès Moreau-Aubry. Decitabine and Melphalan Fail to Reactivate p73 in p53 Deficient Myeloma Cells. International Journal of Molecular Sciences. (2017) inserm-01691503
P Mathot, M Grandin, G Devailly, Frédérique Souazé, V. Cahais, S. Moran, Mario Campone, Z Herceg, M Esteller, Philippe Juin, P. Mehlen, R Dante. DNA methylation signal has a major role in the response of human breast cancer cells to the microenvironment. Oncogenesis. (2017) e390. inserm-01668763
Kristell Oizel, Cynthia Chauvin, Lisa Oliver, Catherine Gratas, Fanny Geraldo, Ulrich Jarry, Emmanuel Scotet, Marion Rabe, Marie-Clotilde Alves-Guerra, Raluca Teusan, Fabien Gautier, Delphine Loussouarn, Vincent Compan, Jean-Claude Martinou, François Vallette, Claire Pecqueur. Efficient Mitochondrial Glutamine Targeting Prevails Over Glioblastoma Metabolic Plasticity. Clinical Cancer Research. (2017) Epub ahead of print. inserm-01595798
Jérôme Abadie, Frédérique Nguyen, Delphine Loussouarn, Laura Pena, Adelina Gama, Natascha Rieder, Anton Belousov, Ingrid Bemelmans, Laëtitia Jaillardon, Catherine Ibisch, Mario Campone. Canine invasive mammary carcinomas as models of human breast cancer. Part 2: immunophenotypes and prognostic significance. Breast Cancer Research and Treatment. (2017) Epub ahead of print. inserm-01629625
Frédérique Nguyen, Laura Pena, Catherine Ibisch, Delphine Loussouarn, Adelina Gama, Natascha Rieder, Anton Belousov, Mario Campone, Jérôme Abadie. Canine invasive mammary carcinomas as models of human breast cancer. Part 1: natural history and prognostic factors. Breast Cancer Research and Treatment. (2017) Epub ahead of print. inserm-01629480
Caroline Corbel, Sara Sartini, Elisabetta Levati, Pierre Colas, Laurent Maillet, Cyril Couturier, Barbara Montanini, Stéphane Bach. Screening for Protein-Protein Interaction Inhibitors Using a Bioluminescence Resonance Energy Transfer (BRET)-Based Assay in Yeast. Slas Discovery. (2017) 751-759. hal-01697260
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