PUBLICATIONS DE 2018

EQUIPE 1         EQUIPE 2          EQUIPE 3          EQUIPE 4             EQUIPE 5              EQUIPE 6                EQUIPE 7               EQUIPE 8               EQUIPE 9

EQUIPE 10      EQUIPE 11         EQUIPE 12        EQUIPE 13           EQUIPE 14            EQUIPE 15               EQUIPE 16             EQUIPE 17

EQUIPE 1

Régine Vivien, Soraya Saïagh, Philippe Lemarre, Valérie Chabaud, Béline Jesson, Catherine Godon, Ulrich Jarry, Thierry Guillaume, Patrice Chevallier, Henri Vié, Béatrice Clémenceau. The doubling potential of T lymphocytes allows clinical-grade production of a bank of genetically modified monoclonal T-cell populations. Cytotherapy. (2018) 436 – 452. inserm-01813104

Bercelin Maniangou, Christelle Retière, Katia Gagne. Next-generation sequencing technology a new tool for killer cell immunoglobulin-like receptor allele typing in hematopoietic stem cell transplantation : Séquençage nouvelle génération, un nouvel outil pour typer les allèles killer cell immunoglobulin-like receptor en greffes de cellules souches hématopoïétiques. Transfusion Clinique et Biologique. (2018) 87 – 89. inserm-01807147

Lola Boutin, Emmanuel Scotet. Towards Deciphering the Hidden Mechanisms That Contribute to the Antigenic Activation Process of Human Vγ9Vδ2 T Cells. Frontiers in Immunology. (2018) 1-1. inserm-01807705

Trudy Straetemans, Guido Kierkels, Ruud Doorn, Koen Jansen, Sabine Heijhuurs, Joao dos Santos, Anna van Muyden, Henri Vié, Béatrice Clémenceau, Reinier Raymakers, Moniek de Witte, Zsolt Sebestyén, Jürgen Kuball. GMP-Grade Manufacturing of T Cells Engineered to Express a Defined γδTCR. Frontiers in Immunology. (2018) 1062. inserm-01823708

Christelle Retière, Catherine Willem, Thierry Guillaume, Henri Vié, Laetitia Gautreau-Rolland, Emmanuel Scotet, Xavier Saulquin, Katia Gagne, Marie Béné, Berthe-Marie Imbert, Béatrice Clémenceau, Pierre Peterlin, Alice Garnier, Patrice Chevallier. Impact on early outcomes and immune reconstitution of high- dose post-transplant cyclophosphamide vs anti-thymocyte globulin after reduced intensity conditioning peripheral blood stem cell allogeneic transplantation. Oncotarget. (2018) 11451 – 11464. inserm-01737944

Marie-Claire Devilder, Melinda Moyon, Xavier Saulquin, Laetitia Gautreau-Rolland. Generation of Discriminative Human Monoclonal Antibodies from Rare Antigen-specific B Cells Circulating in Blood. Journal of visualized experiments : JoVE. (2018) e56508. inserm-01745629

Marie Frutoso, Sébastien Morisseau, Fella Tamzalit, Agnès Quéméner, Dihia Meghnem, Isabelle Leray, Yannick Jacques, Erwan Mortier. Emergence of NK Cell Hyporesponsiveness after Two IL-15 Stimulation Cycles. Journal of Immunology. (2018) Epub ahead of print. inserm-01805185

Oisín Huhn, Olympe Chazara, Martin Ivarsson, Christelle Retière, Timothy Venkatesan, Paul Norman, Hugo Hilton, Jyothi Jayaraman, James Traherne, John Trowsdale, Mitsutero Ito, Christiane Kling, Peter Parham, Hormas Ghadially, Ashley Moffett, Andrew Sharkey, Francesco Colucci. High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia. Journal of Immunology. (2018) 2593-2601. inserm-01968722

Francesco Saraceni, Myriam Labopin, Rose-Marie Hamladji, Ghulam Mufti, Gerard Socie, Avichai Shimoni, Jeremy Delage, Eric Deconinck, Patrice Chevallier, Didier Blaise, Jaime Sanz, Anne Huynh, Edouard Forcade, Bipin N. Savani, Mohamad Mohty, Arnon Nagler, Acute Leukemia Working Party Europ. Thiotepa-busulfan-fludarabine compared to busulfan-fludarabine for sibling and unrelated donor transplant in acute myeloid leukemia in first remission. Oncotarget. (2018) 3379-3393. hal-02143546

Salyka Sengsayadeth, Myriam Labopin, Ariane Boumendil, Juergen Finke, Arnold Ganser, Matthias Stelljes, Gerhard Ehninger, Dietrich Beelen, Dietger Niederwieser, Didier Blaise, Peter Dreger, Ghulam Mufti, Patrice Chevallier, Audrey Mailhol, Katie S. Gatwood, Norbert Gorin, Jordi Esteve, Fabio Ciceri, Frederic Baron, Christoph Schmid, Sebastian Giebel, Mohamad Mohty, Bipin N. Savani, Arnon Nagler. Transplant Outcomes for Secondary Acute Myeloid Leukemia: Acute Leukemia Working Party of the European Society for Blood and Bone Marrow Transplantation Study. Biology of Blood and Marrow Transplantation. (2018) 1406-1414. hal-02143562

Raynier Devillier, Myriam Labopin, Patrice Chevallier, Marie-Pierre Ledoux, Gerard Socie, Anne Huynh, Jean-Henri Bourhis, Jean-Yves Cahn, Gabrielle Roth-Guepin, Ghulam Mufti, Deborah Desmier, Mauricette Michallet, Nathalie Fegueux, Fabio Ciceri, Frederic Baron, Didier Blaise, Arnon Nagler, Mohamad Mohty. Impact of antithymocyte globulin doses in reduced intensity conditioning before allogeneic transplantation from matched sibling donor for patients with acute myeloid leukemia: a report from the acute leukemia working party of European group of Bone Marrow Transplantation. Bone Marrow Transplantation. (2018) 431-437. hal-02143554

Emilie Dugast, Gaëlle David, Romain Oger, Richard Danger, Jean-Paul Judor, Katia Gagne, Mélanie Chesneau, Nicolas Degauque, Jean-Paul Soulillou, Pascale Paul, Christophe Picard, Pierrick Guerif, Sophie Conchon, Magali Giral, Nadine Gervois, Christelle Retière, Sophie Brouard. Corrigendum: Broad Impairment of Natural Killer Cells From Operationally Tolerant Kidney Transplanted Patients. Frontiers in Immunology. (2018) 589. inserm-01811913

Jocelyn Ollier, Thibault Kervarrec, Mahtab Samimi, Houssem Benlalam, Pascal Aumont, Régine Vivien, Antoine Touzé, Nathalie Labarrière, Henri Vié, Béatrice Clémenceau. Merkel cell carcinoma and cellular cytotoxicity: sensitivity to cellular lysis and screening for potential target antigens suitable for antibodydependent cellular cytotoxicity. Cancer Immunology, Immunotherapy. (2018) Epub ahead of print. inserm-01807689

Noémie Joalland, Cynthia Chauvin, Lisa Oliver, François Vallette, Claire Pecqueur, Ulrich Jarry, Emmanuel Scotet. IL-21 Increases the Reactivity of Allogeneic Human Vγ9Vδ2 T Cells Against Primary Glioblastoma Tumors. Journal of immunotherapy : official journal of the Society for Biological Therapy. (2018) 224-231. inserm-01804994

Ulrich Jarry, Noémie Joalland, Cynthia Chauvin, Béatrice Clémenceau, Claire Pecqueur, Emmanuel Scotet. Stereotactic Adoptive Transfer of Cytotoxic Immune Cells in Murine Models of Orthotopic Human Glioblastoma Multiforme Xenografts. Journal of visualized experiments : JoVE. (2018) 1(139). inserm-01885088

Pierre Peterlin, Joëlle Gaschet, Thierry Guillaume, Alice Garnier, Marion Eveillard, Amandine Le Bourgeois, Michel Chérel, Camille Debord, Yannick Le Bris, Olivier Theisen, Béatrice Mahé, Viviane Dubruille, Soraya Wuilleme, Catherine Godon, Cyrille Touzeau, Thomas Gastinne, Nicolas Blin, Anne Lok, Antoine Bonnet, Steven Le Gouill, Philippe Moreau, Marie Béné, Patrice Chevallier. Fms-like Tyrosine Kinase 3 Ligand Concentration Kinetic Profile during Induction Is Strongly Predictive of Survivals in AML: Results of the FLAM/Flal Study. Blood (2018) 1484. inserm-02341909

EQUIPE 2

Brigitte Dréno, Robert Bissonnette, Angélique Gagné-Henley, Benjamin Barankin, Charles Lynde, Nabil Kerrouche, Jerry Tan. Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3% /Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison. American Journal of Clinical Dermatology. (2018) 275-286. inserm-01812230

Marie-Ange Dagnelie, Stéphane Corvec, Mélanie Saint-Jean, Valérie Bourdès, Jean-Michel Nguyen, Amir Khammari, Brigitte Dréno. Decrease in Diversity of Propionibacterium acnes Phylotypes in Patients with Severe Acne on the Back. Acta Dermato-Venereologica. (2018) 262 – 267. inserm-01807415

I Carlavan, B Bertino, M Rivier, P Martel, V Bourdes, M Motte, S Déret, P Reiniche, C Menigot, Amir Khammari, Brigitte Dréno, P Fogel, Johannes Voegel. Atrophic scar formation in acne patients involves long-acting immune responses with plasma cells and alteration of sebaceous glands. British Journal of Dermatology. (2018) Epub ahead of print. inserm-01810723

Cécile Frenard, Marie-Ange Dagnelie, Amir Khammari, Mélanie Saint-Jean, Aurélie Boisrobert, Stéphane Corvec, Brigitte Dréno. Do Cutibacterium acnes and Staphylococcus aureus define two different types of folliculitis? Bacteriological study of scalp folliculitis. Journal of the European Academy of Dermatology and Venereology. (2018) Epub ahead of print. inserm-01813330

Charles Decraene, Amanda Silveira, François-Clément Bidard, Audrey Vallée, Marc Michel, Samia Melaabi, Anne Vincent-Salomon, Adrien Saliou, Alexandre Houy, Maud Milder, Olivier Lantz, Marc Ychou, Marc Denis, Jean-Yves Pierga, Marc-Henri Stern, Charlotte Proudhon. Multiple Hotspot Mutations Scanning by Single Droplet Digital PCR. Clinical Chemistry. (2018) 317 – 328. inserm-01823628

Marie-Ange Dagnelie, Amir Khammari, Brigitte Dréno, Stéphane Corvec. Cutibacterium acnes molecular typing: time to standardize the method. Clinical Microbiology and Infection. (2018) Epub ahead of print. inserm-01810309

Stéphane Corvec. Clinical and Biological Features of Cutibacterium (Formerly Propionibacterium) avidum, an Underrecognized Microorganism. Clinical Microbiology Reviews. (2018) 31;3. inserm-01810023

Laurent Petit, Didier Zugaj, Vincenzo Bettoli, Brigitte Dréno, Sewon Kang, Jerry Tan, V. Torres, Alison Layton, Philippe Martel. Validation of 3D skin imaging for objective repeatable quantification of severity of atrophic acne scarring. Skin Research and Technology. (2018) 542-550. inserm-01811944

Lamia Jelti, Nadège Cordel, André Gillibert, Philippe Lacour, Claire Uthurriague, Marie-Sylvie Doutre, Emmanuel Delaporte, Sophie Duvert-Lehembre, Gaëlle Quéreux, Alain Dupuy, Henri Adamski, Christophe Bédane, Laurent Misery, Claire Abasq Thomas, Camille Fleuret, Philippe Bernard, Guillaume Chaby, Michel D’Incan, Laurence Verneuil, Noémie Litrowski, Pascal Joly. Incidence and Mortality of Pemphigus in France. Journal of Investigative Dermatology. (2018) 469-473. hal-01927030

Louise Guenot, Morgane Vourc’h Jourdain, Mélanie Saint-Jean, Stéphane Corvec, Aurélie Gaultier, Amir Khammari, Marie Le Moigne, Aurélie Boisrobert, Charlotte Paugam, Brigitte Dréno. Confocal microscopy in adult women with acne. International Journal of Dermatology. (2018) 278-283. inserm-01813447

Guillaume Herbreteau, Audrey Vallée, Anne-Chantal Knol, Sandrine Théoleyre, Gaëlle Quéreux, Emilie Varey, Amir Khammari, Brigitte Dréno, Marc Denis. Quantitative monitoring of circulating tumor DNA predicts response of cutaneous metastatic melanoma to anti-PD1 immunotherapy. Oncotarget. (2018) 25265 – 25276. inserm-01810155

Brigitte Dréno, S. Pécastaings, Stéphane Corvec, S Veraldi, Amir Khammari, C. Roques. Cutibacterium acnes (Propionibacterium acnes) and acne vulgaris: a brief look at the latest updates. Journal of the European Academy of Dermatology and Venereology. (2018) 05-14. inserm-01823717

S. Pécastaings, C. Roques, Th. Nocera, C. Peraud, Valérie Mengeaud, Amir Khammari, Brigitte Dréno. Characterisation of Cutibacterium acnes phylotypes in acne and in vivo exploratory evaluation of Myrtacine®. Journal of the European Academy of Dermatology and Venereology. (2018) 15 – 23. inserm-01823729

Brigitte Dréno, Vincenzo Bettoli, Elena Araviiskaia, Miguel Sanchez Viera, Anne Bouloc. The influence of exposome on acne. Journal of the European Academy of Dermatology and Venereology. (2018) 812 – 819. inserm-01813534

Jean-Paul Claudel, N. Auffret, Marie Therese Leccia, F. Poli, Brigitte Dréno. Acne and nutrition: hypotheses, myths and facts. Journal of the European Academy of Dermatology and Venereology. (2018) Epub ahead of print. inserm-01810779

Brigitte Dréno. Ipilimumab more and more discussed: urgent need for predictive markers of response. Journal of the European Academy of Dermatology and Venereology. (2018) 849. inserm-01823774

Lucie Peuvrel, Julie Cassecuel, C. Bernier, Gaëlle Quéreux, Mélanie Saint-Jean, Marie Le Moigne, Cécile Frénard, Amir Khammari, Brigitte Dréno. TOXICAN: a guide for grading dermatological adverse events of cancer treatments. Supportive Care in Cancer. (2018) Epub ahead of print. inserm-01812109

Jean-Marie Berthelot, Stéphane Corvec, Gilles Hayem. SAPHO, autophagy, IL-1, FoxO1, and Propionibacterium (Cutibacterium) acnes. Joint Bone Spine. (2018) 171 – 176. inserm-01814460

Anne Knol, Jean-Michel Nguyen, Marie-Christine Pandolfino, Marc Denis, Amir Khammari, Brigitte Dréno. PD-L1 expression by tumor cell-lines: a predictive marker in melanoma. Experimental Dermatology. (2018) 647-655. inserm-01805109

Acke Ohlin, Emma Mattsson, Matthias Mörgelin, Julia Davies, Gunnel Svensäter, Stéphane Corvec, Pentti Tengvall, Kristian Riesbeck. Titanium granules pre treated with hydrogen peroxide inhibit growth of bacteria associated with post operative infections in spine surgery. European Spine Journal. (2018) Epub ahead of print. inserm-01812146

Mélanie Saint-Jean, Anne-Chantal Knol, Christelle Volteau, Gaëlle Quéreux, Lucie Peuvrel, Anabelle Brocard, Marie-Christine Pandolfino, Soraya Saïagh, Jean-Michel Nguyen, Christophe Bedane, Nicole Basset-Seguin, Amir Khammari, Brigitte Dréno. Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes in Advanced Melanoma Patients. Journal of Immunology Research. (2018) eCollection2018. inserm-01810834

Mélanie Saint-Jean, Marie Le Moigne, Justine Daguze, Céline Bossard, Lucie Peuvrel, Gaëlle Quereux, Brigitte Dréno. Pyoderma Gangrenosum Under Dabrafenib and Trametinib for Metastatic Melanoma. Acta Dermato-Venereologica. (2018) 530-531. inserm-02099570

Barbara Bregeon, Jean-Michel Nguyen, Emilie Varey, Gaëlle Quereux, Mélanie Saint-Jean, Lucie Peuvrel, Amir Khammari, Brigitte Dréno. Positive margins after surgical excision of locoregional cutaneous melanoma metastasis and their impact on patient outcome. European Journal of Dermatology. (2018) 661-667. inserm-02099813

Cécile Frénard, Hervé Dutartre, Aurélie Boisrobert, Amir Khammari, Brigitte Dréno. Decreased photosensitivity to UVA on vemurafenib combined with cobimetinib. Journal of the European Academy of Dermatology and Venereology. (2018) e87-e88. inserm-02099451

Edouard Chasseuil, Mélanie Saint-Jean, Hannah Chasseuil, Lucie Peuvrel, Gaëlle Quereux, Jean-Michel Nguyen, Aurélie Gaultier, Emilie Varey, Amir Khammari, Brigitte Dréno. Blood Predictive Biomarkers for Nivolumab in Advanced Melanoma. Acta Dermato-Venereologica. (2018) 406-410. inserm-02099448

Stéphane Corvec, Marie-Ange Dagnelie, Amir Khammari, Brigitte Dréno. Taxonomy and phylogeny of Cutibacterium (formerly Propionibacterium) acnes in inflammatory skin diseases. Annales de Dermatologie et de Vénéréologie. (2018) 26-30. inserm-02099793

Dalila Sellah, Mélanie Saint-Jean, Lucie Peuvrel, Amir Khammari, Gaëlle Quereux, Brigitte Dréno. Anti-PD1 in Merkel cell carcinoma and cutaneous squamous cell carcinoma, description of five cases and recent data from the literature. Journal of the European Academy of Dermatology and Venereology. (2018) e159-e161. inserm-02099780

Stanimir Kambarev, Frédéric Pecorari, Stéphane Corvec. Novel Tn916-like elements confer aminoglycoside/macrolide co-resistance in clinical isolates of Streptococcus gallolyticus ssp. gallolyticus. Journal of Antimicrobial Chemotherapy. (2018) 1201 – 1205. inserm-01813206

Sylvain Simon, Zhong Wu, J. Cruard, Virginie Vignard, Agnès Fortun, Amir Khammari, Brigitte Dréno, Francois Lang, Samuel Rulli, Nathalie Labarrière. TCR Analyses of Two Vast and Shared Melanoma Antigen-Specific T Cell Repertoires: Common and Specific Features. Frontiers in Immunology. (2018) 1962. inserm-01885141

EQUIPE 3

Catherine Le Stunff, Anne-Laure Castell, Nicolas Todd, Clémence Mille, Marie-Pierre Belot, Nathalie Frament, Sylvie Brailly-Tabard, Alexandra Benachi, Delphine Fradin, Pierre Bougnères. Fetal growth is associated with the CpG methylation of the P2 promoter of the IGF1 gene. Clinical Epigenetics. (2018) 57. inserm-01782203

Virginie Vignard, Delphine Fradin. Non-Coding RNAs in Cutaneous Melanoma Development, Progression and Dissemination. OBM Genetics. (2018) 1-1. inserm-01804848

Nicolas Jouand, Céline Bressollette-Bodin, Nathalie Gérard, Magali Giral, Pierrick Guérif, Audrey Rodallec, Romain Oger, Tiphaine Parrot, Mathilde Allard, Anne Cesbron-Gautier, Nadine Gervois, Béatrice Charreau. HCMV triggers frequent and persistent UL40- specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition. PLoS Pathogens. (2018) e1007041. inserm-01812003

Chantal Bou-Hanna, Anne Jarry, Jean-François Mosnier, Céline Bossard, Christian Laboisse. The double stranded RNA analog poly-IC elicits both robust IFN-λ production and oncolytic activity in human gastrointestinal cancer cells. Oncotarget. (2018) 34471 – 34484. inserm-01938002

Camille Martin-Gallausiaux, Pierre Larraufie, Anne Jarry, Fabienne Beguet-Crespel, Ludovica Marinelli, Florence Ledue, Frank Reimann, Herve Blottiere, Nicolas Lapaque. Butyrate produced by commensal bacteria down-regulates indolamine 2, 3-dioxygenase 1 (IDO-1) expression via a dual mechanism in human intestinal epithelial cells. Frontiers in Immunology. (2018) 2838. inserm-01937996

Marie-Laure Vuillaume, Mederic Jeanne, Li Xue, Sophie Blesson, Anne-Sophie Denomme-Pichon, Servane Alirol, Celine Brulard, Estelle Colin, Bertrand Isidor, Brigitte Gilbert-Dussardier, Sylvie Odent, Philippe Parent, Audrey Donnart, Richard Redon, Stéphane Bézieau, Philippe Rondard, Frederic Laumonnier, Annick Toutain. A novel mutation in the transmembrane 6 domain of GABBR2 leads to a Rett-like phenotype. Annals of Neurology. (2018) 437-439. hal-01730199

Tilda Passat, Yann Touchefeu, Nadine Gervois, Anne Jarry, Céline Bossard, Jaafar Bennouna. Physiopathological mechanisms of immune-related adverse events induced by anti-CTLA-4, anti-PD-1 and anti-PD-L1 antibodies in cancer treatment. Bulletin du Cancer. (2018) 1033-1041. inserm-01981595

Nicolas Jouand, Céline Bressollette-Bodin, Nathalie Gérard, Magali Giral, Pierrick Guerif, Audrey Rodallec, Romain Oger, Tiphaine Parrot, Anne Cesbron-Gautier, Nadine Gervois, Béatrice Charreau. Deciphering anti-HCMV HLA-E-restricted unconventional CD8 T-cell responses in seropositive HCMV+ hosts. [Poster]. (2018) np. inserm-02158889

Emilie Dugast, Gaëlle David, Romain Oger, Richard Danger, Jean-Paul Judor, Katia Gagne, Mélanie Chesneau, Nicolas Degauque, Jean-Paul Soulillou, Pascale Paul, Christophe Picard, Pierrick Guerif, Sophie Conchon, Magali Giral, Nadine Gervois, Christelle Retière, Sophie Brouard. Corrigendum: Broad Impairment of Natural Killer Cells From Operationally Tolerant Kidney Transplanted Patients. Frontiers in Immunology. (2018) 589. inserm-01811913

Jocelyn Ollier, Thibault Kervarrec, Mahtab Samimi, Houssem Benlalam, Pascal Aumont, Régine Vivien, Antoine Touzé, Nathalie Labarrière, Henri Vié, Béatrice Clémenceau. Merkel cell carcinoma and cellular cytotoxicity: sensitivity to cellular lysis and screening for potential target antigens suitable for antibodydependent cellular cytotoxicity. Cancer Immunology, Immunotherapy. (2018) Epub ahead of print. inserm-01807689

Sylvain Simon, Zhong Wu, J. Cruard, Virginie Vignard, Agnès Fortun, Amir Khammari, Brigitte Dréno, Francois Lang, Samuel Rulli, Nathalie Labarrière. TCR Analyses of Two Vast and Shared Melanoma Antigen-Specific T Cell Repertoires: Common and Specific Features. Frontiers in Immunology. (2018) 1962. inserm-01885141

Emmanuelle Godefroy, Joudy Alameddine, Emmanuel Montassier, Justine Mathé, Juliette Desfrançois-Noël, Nadège Marec, Céline Bossard, Anne Jarry, Chantal Bridonneau, Amandine Le Roy, Guillaume Sarrabayrouse, Elise Kerdreux, Arnaud Bourreille, Harry Sokol, Francine Jotereau, Frédéric Altare. Expression of CCR6 and CXCR6 by Gut-Derived CD4+/CD8α+ T-Regulatory Cells, Which Are Decreased in Blood Samples From Patients With Inflammatory Bowel Diseases. Gastroenterology. (2018) 1205-1217. inserm-01968888

Léa Paolini, Caroline Poli, Simon Blanchard, Thierry Urban, Anne Croué, Marie-Christine Rousselet, Sarah Le Roux, Nathalie Labarrière, Pascale Jeannin, José Hureaux. Thoracic and cutaneous sarcoid-like reaction associated with anti-PD-1 therapy: longitudinal monitoring of PD-1 and PD-L1 expression after stopping treatment. Journal for Immunotherapy of Cancer. (2018) 52. inserm-01817689

EQUIPE 4

Douae Bensaid, Thibaut Blondy, Sophie Deshayes, Virginie Dehame, Philippe Bertrand, Marc Grégoire, Mohammed Errami, Christophe Blanquart. Assessment of new HDAC inhibitors for immunotherapy of malignant pleural mesothelioma. Clinical Epigenetics. (2018) 10-1. inserm-01820890

Joanna Boucard, Camille Linot, Thibaut Blondy, Steven Nedellec, Philippe Hulin, Christophe Blanquart, Lenaic Lartigue, Eléna Ishow. Small Molecule-Based Fluorescent Organic Nanoassemblies with Strong Hydrogen Bonding Networks for Fine Tuning and Monitoring Drug Delivery in Cancer Cells. Small. (2018) e1802307. inserm-01885511

Kamila Hladíková, Simona Partlová, Vladimír Koucký, Jan Bouček, Jean-François Fonteneau, Michal Zábrodský, Ruth Tachezy, Marek Grega, Radek Špíšek, Anna Fialová. Dysfunction of HPV16-specific CD8+ T cells derived from oropharyngeal tumors is related to the expression of Tim-3 but not PD-1. Oral Oncology. (2018) 75 – 82. inserm-01823518

Patrick Smeele, Sènan d’Almeida, Clément Meiller, Anne-Laure Chéné, Charly Liddell, Laurent Cellerin, François Montagne, Sophie Deshayes, Sarah Benziane, Marie-Christine Copin, Paul Hofman, Françoise Le Pimpec-Barthes, Henri Porte, Arnaud Scherpereel, Marc Grégoire, Didier Jean, Christophe Blanquart. Brain-derived neurotrophic factor, a new soluble biomarker for malignant pleural mesothelioma involved in angiogenesis. Molecular Cancer. (2018) 148. inserm-01904612

Melita Vidakovic, Jessica Marinello, Maija Lahtela-Kakkonen, Daumantas Matulis, Vaida Linkuvienė, Benoît Y. Michel, Ruta Navakauskienė, Michael S. Christodoulou, Danielle Passarella, Saulius Klimasauskas, Christophe Blanquart, Muriel Cuendet, Judit Ovadi, Stéphane Poulain, Fabien Fontaine-Vive, Alain Burger, Nadine Martinet. New Insights into the Epigenetic Activities of Natural Compounds. OBM Genetics. (2018) 3033-41. inserm-01981397

Marine Charrier, Judith Lorant, Rafael Contreras Lopez, Christophe Blanquart, Blandine Lieubeau-Teillet, Cindy Schleder, Isabelle Leroux, Tejedor Gauthier, Candice Babarit, Yann Pereon, Patricia Luz-Crawford, Guillaume Lamirault, Farida Djouad, Karl Rouger. Demonstration of immunomodulatory properties for the human MuStem cell population, a promising candidate for cell therapy of muscular dystrophies. [Actes Congrès]. (2018) np. hal-01959646

Valérie Héroguez, Christophe Blanquart, Philippe Bertrand. Application au mésothéliome, le cancer de l’amiante. L’Actualité Chimique. (2018) 33-38. inserm-01981403

Vincent Bonnarme, Antoine Piccirilli, Philippe Ayrault, Laurent Lemée, Gilles Frapper, Jérémie Pourchez, Douae Bensaid, Thibaut Blondy, Sophie Deshayes, Virginie Dehame, Marc Grégoire, Mohammed Errami, Christophe Blanquart, Micaela Faria Freitas, Muriel Cuendet, Philippe Bertrand. HDAC inhibitors: a 2013–2017 patent survey. Expert Opinion on Therapeutic Patents. (2018) 365-381. hal-02147173

Anne Lok, Géraldine Descamps, Benoit Tessoulin, David Chiron, Marion Eveillard, Catherine Godon, Yannick Le Bris, Astrid Vabret, Céline Bellanger, Laurent Maillet, Sophie Barillé-Nion, Marc Gregoire, Jean-François Fonteneau, Steven Le Gouill, Philippe Moreau, Frederic Tangy, Martine Amiot, Agnès Moreau-Aubry, Catherine Pellat-Deceunynck. p53 regulates CD46 expression and measles virus infection in myeloma cells. Blood Advances. (2018) 3492-3505. inserm-01957487

Judith Lorant, Marine Charrier, Rafael Contreras Lopez, Christophe Blanquart, Blandine Lieubeau-Teillet, Cindy Schleder, Isabelle Leroux, Tejedor Gauthier, Candice Babarit, Yann Pereon, Patricia Luz-Crawford, Guillaume Lamirault, Farida Djouad, Karl Rouger. Demonstration of immunomodulatory properties for the human MuStem cell population, a promising candidate for cell therapy of muscular dystrophies. [Actes Congrès]. (2018) np. hal-01927456

Joëlle Nader, Jérôme Abadie, Sophie Deshayes, Alice Boissard, Stéphanie Blandin, Christophe Blanquart, Nicolas Boisgerault, Olivier Coqueret, Catherine Guette, Marc Grégoire, Daniel Pouliquen. Characterization of increasing stages of invasiveness identifies stromal/cancer cell crosstalk in rat models of mesothelioma. Oncotarget. (2018) Epub ahead of print. inserm-01726393

Christophe Blanquart, Camille Linot, Pierre-François Cartron, Daniela Tomaselli, Antonello Mai, Philippe Bertrand. Epigenetic metalloenzymes. Current Medicinal Chemistry. (2018) 1-36. inserm-01885512

EQUIPE 5

Pedro Esteves, Joana Abrantes, Hanna-Mari Baldauf, Lbachir Benmohamed, Yuxing Chen, Neil Christensen, Javier González-Gallego, Lorenzo Giacani, Jiafen Hu, Gilla Kaplan, Oliver Keppler, Katherine Knight, Xiang-Peng Kong, Dennis Lanning, Jacques Le Pendu, Ana Lemos De Matos, Jia Liu, Shuying Liu, Ana Lopes, Shan Lu, Sheila Lukehart, Yukari Manabe, Fabiana Neves, Grant McFadden, Ruimin Pan, Xuwen Peng, Patricia de Sousa-Pereira, Ana Pinheiro, Masmudur Rahman, Natalie Ruvoën-Clouet, Selvakumar Subbian, Maria Tuñón, Wessel Van Der Loo, Michael Vaine, Laura Via, Shixia Wang, Rose Mage. The wide utility of rabbits as models of human diseases. Experimental & Molecular Medicine. (2018) 66. inserm-01804663

Eun-Hyo Cho, Mahmoud Soliman, Mia Alfajaro, Ji-Yun Kim, Ja-Young Seo, Jun-Gyu Park, Deok-Song Kim, Yeong-Bin Baek, Mun-Il Kang, Sang-Ik Park, Jacques Le Pendu, Kyoung-Oh Cho. Bovine Nebovirus Interacts with a Wide Spectrum of Histo-Blood Group Antigens. Journal of Virology. (2018) Epub ahead of print. inserm-01708919

Peter Hraber, Steven Bradfute, Elizabeth Clarke, Chunyan Ye, Bruno Pitard. Amphiphilic block copolymer delivery of a DNA vaccine against Zika virus. Vaccine. (2018) 6911 – 6917. inserm-01908713

Laurence Dallet, Marion Decossas, Jean-Christophe Taveau, Sophie Lecomte, Sylvie Poussard, Olivier Lambert, Bruno Pitard. Single lipoaminoglycoside promotes efficient intracellular antibody delivery: A comprehensive insight into the mechanism of action. Nanomedicine: Nanotechnology, Biology and Medicine. (2018) 141 – 151. inserm-01814772

Laure Barbé, Béatrice Le Moullac-Vaidye, Klara Echasserieau, Karine Bernardeau, Thomas Carton, Nicolai Bovin, Johan Nordgren, Lennart Svensson, Nathalie Ruvoën-Clouet, Jacques Le Pendu. Histo-blood group antigen-binding specificities of human rotaviruses are associated with gastroenteritis but not with in vitro infection. Scientific Reports. (2018) 12961. inserm-01885025

Emmanuelle Godefroy, Joudy Alameddine, Emmanuel Montassier, Justine Mathé, Juliette Desfrançois-Noël, Nadège Marec, Céline Bossard, Anne Jarry, Chantal Bridonneau, Amandine Le Roy, Guillaume Sarrabayrouse, Elise Kerdreux, Arnaud Bourreille, Harry Sokol, Francine Jotereau, Frédéric Altare. Expression of CCR6 and CXCR6 by Gut-Derived CD4+/CD8α+ T-Regulatory Cells, Which Are Decreased in Blood Samples From Patients With Inflammatory Bowel Diseases. Gastroenterology. (2018) 1205-1217. inserm-01968888

EQUIPE 6

Hélène Pailhoriès, Clémence Tiry, Matthieu Eveillard, Marie Kempf. Acinetobacter pittii isolated more frequently than Acinetobacter baumannii in blood cultures: the experience of a French hospital. Journal of Hospital Infection. (2018) Epub ahead of print. inserm-01811906

Milène Nitenberg, Anaïs Benarouche, Ofélia Maniti, Estelle Marion, Laurent Marsollier, Julie Géan, Erick Dufourc, Jean-François Cavalier, Stéphane Canaan, Agnès Girard-Egrot. The potent effect of mycolactone on lipid membranes. PLoS Pathogens. (2018) e1006814. inserm-01709054

Fabrice Compain, Daria Soroka, Beate Heym, Jean-Louis Gaillard, Jean-Louis Herrmann, Delphine Dorchène, Michel Arthur, Vincent Dubée. In vitro activity of tedizolid against the Mycobacterium abscessus complex. Diagnostic Microbiology and Infectious Disease. (2018) 186 – 189. inserm-01813096

Hassan Nehme, Patrick Saulnier, Alyaa Ramadan, Viviane Cassisa, Catherine Guillet, Matthieu Eveillard, Anita Umerska. Antibacterial activity of antipsychotic agents, their association with lipid nanocapsules and its impact on the properties of the nanocarriers and on antibacterial activity. PLoS ONE. (2018) e0189950. inserm-01813878

Céline Lafarge, Bruno Pontoire, Nathalie Cayot, Patricia Le Bail, Noémie Coron, Marc Pihet, Emilie Fréalle, Yolande Lemeille, Claudine Pinel, Hervé Pelloux, Gilles Gargala, Loïc Favennec, Isabelle Accoceberry, Isabelle Durand-Joly, Frédéric Dalle, Frédéric Huet, Annlyse Fanton, Amale Boldron, Guy-André Loeuille, Philippe Domblides, Bérengère Coltey, Isabelle Pin, Catherine Llerena, Françoise Troussier, Christine Person, Christophe Marguet, Nathalie Wizla, Caroline Thumerelle, Dominique Turck, Stéphanie Bui, Michael Fayon, Alain Duhamel, Anne Prévotat, Sylvie Leroy, Benoit Wallaert, Jean-Philippe Bouchara, Laurence Delhaes. Toward the Standardization of Mycological Examination of Sputum Samples in Cystic Fibrosis : Results from a French Multicenter Prospective Study. Mycopathologia. (2018) 101-117. hal-01618715

Quentin Vincent, Aziz Belkadi, Cindy Fayard, Estelle Marion, Ambroise Adeye, Marie-Françoise Ardant, Christian Johnson, Didier Agossadou, Lazaro Lorenzo, Julien Guergnon, Christine Bole-Feysot, Jeremy Manry, Patrick Nitschké, Ioannis Theodorou, Jean-Laurent Casanova, Laurent Marsollier, Annick Chauty, Laurent Abel, Alexandre Alcaïs. Microdeletion on chromosome 8p23.1 in a familial form of severe Buruli ulcer. PLoS Neglected Tropical Diseases. (2018) e0006429. inserm-01804969

Pierre Danneels, Rafael Mahieu, Mamoun Dib, Pierre Abgueguen, Valérie Rabier, Marion Klosek, Yohann Le Govic, Vincent Dubée. On the Nose: Disseminated Mucormycosis »✯✯✯..The American Journal of Medicine. (2018) 1182-1184. inserm-01815460

Elodie Couvé-Deacon, Thomas Jové, Pamela Afouda, Olivier Barraud, Valentin Tilloy, Erwan Scaon, Bastien Hervé, Christophe Burucoa, Marie Kempf, Javier Marcos, Marie-Cécile Ploy, Fabien Garnier. Class 1 integrons in Acinetobacter baumannii: a weak expression of gene cassettes to counterbalance the lack of LexA-driven integrase repression. International Journal of Antimicrobial Agents. (2018) Epub ahead of print. inserm-01959852

Anita Umerska, Magnus Strandh, Viviane Cassisa, Nada Matougui, Matthieu Eveillard, Patrick Saulnier. Synergistic Effect of Combinations Containing EDTA and the Antimicrobial Peptide AA230, an Arenicin-3 Derivative, on Gram-Negative Bacteria. Biomolecules. (2018) 122. inserm-01959870

Laura Riva, Ok-Ryul Song, Jannick Prentoe, Francois Helle, Laurent L’homme, Charles-Henry Gattolliat, Alexandre Vandeputte, Lucie Fénéant, Sandrine Belouzard, Thomas Baumert, Tarik Asselah, Jens Bukh, Priscille Brodin, Laurence Cocquerel, Yves Rouillé, Jean Dubuisson. Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry. Journal of Virology. (2018) e01982-17. hal-02112504

EQUIPE 7

Olivier Mansier, Damien Luque Paz, Jean-Christophe Ianotto, Yannick Le Bris, Aurélie Chauveau, Françoise Boyer, Carole Conejero, Olivier Fitoussi, Jérémie Riou, Didier Adiko, Mohamed Touati, Jasmine Chauzeix, Jean-François Viallard, Marie Béné, Stéphane Giraudier, Valérie Ugo, Eric Lippert. Clinical and biological characterization of MPN patients harboring two driver mutations, a French intergroup of myeloproliferative neoplasms (FIM) study. American Journal of Hematology. (2018) E84 – E86. inserm-01813777

Corentin Orvain, Francois Beloncle, Jean-Francois Hamel, Aurélien Sutra Del Galy, Sylvain Thépot, Mélanie Mercier, Achille Kouatchet, Jonathan Fahri, Sylvie Francois, Norbert Ifrah, Alain Mercat, Pierre Asfar, Mathilde Hunault-Berger, Aline Tanguy-Schmidt. Allogeneic stem cell transplantation recipients requiring intensive care: time is of the essence. Annals of Hematology. (2018) Epub ahead of print. inserm-01812041

Damien Luque Paz, Françoise Boyer, Annaelle Beucher, Anne Bouvier, Rebecca Jouanneau-Courville, Philippe Guardiola, Diane Lambert, Yves Delneste, Mathilde Hunault, Odile Blanchet, Valérie Ugo. Concomitant CALR and LNK mutations leading to essential thrombocythemia with erythrocytosis. Blood Cells, Molecules and Diseases. (2018) 75-76. inserm-01804692

Jean-François Augusto, Marie-Elise Truchetet, Nicolas Charles, Patrick Blanco, Christophe Richez. IgE in lupus pathogenesis: Friends or foes? Autoimmunity Reviews. (2018) 361 – 365. inserm-01813114

Yves Delneste, Vincent Larochette, Pascale Jeannin. Immune Properties of HSP70. Chap de l’ouvrage : Human Diseases and Disorders. (2018) 173 – 203. inserm-01884988

Pascale Jeannin, Léa Paolini, Clément Adam, Yves Delneste. The roles of CSFs on the functional polarization of tumor-associated macrophages. FEBS Journal. (2018) 680 – 699. inserm-01718654

Jérôme Paillassa, Thibaut Leguay, Xavier Thomas, Françoise Huguet, Marie Audrain, Véronique Lheritier, Christine Vianey-Saban, Cécile Acquaviva-Bourdain, Cécile Pagan, Hervé Dombret, Norbert Ifrah, Nicolas Boissel, Mathilde Hunault-Berger. Monitoring of asparagine depletion and anti-L-asparaginase antibodies in adult acute lymphoblastic leukemia treated in the pediatric-inspired GRAALL-2005 trial. Blood Cancer Journal. (2018) 45. inserm-01810271

Thomas Briot, Emilie Roger, Sylvain Thépot, Frédéric Lagarce. Advances in treatment formulations for acute myeloid leukemia. Drug Discovery Today Biosilico. (2018) Epub ahead of print. inserm-01809889

Nicolas Duployez, Elise Boudry-Labis, Christophe Roumier, Nicolas Boissel, Arnaud Petit, Sandrine Geffroy, Nathalie Helevaut, Karine Celli-Lebras, Christine Terré, Odile Fenneteau, Wendy Cuccuini, Isabelle Luquet, Hélène Lapillonne, Catherine Lacombe, Pascale Cornillet, Norbert Ifrah, Hervé Dombret, Guy Leverger, Eric Jourdan, Claude Preudhomme. SNP-array lesions in core binding factor acute myeloid leukemia. Oncotarget. (2018) 6478 – 6489. inserm-01813829

Anne-Sophie Garnier, Agnès Duveau, Martin Planchais, Jean-François Subra, Johnny Sayegh, Jean-François Augusto. Serum Magnesium after Kidney Transplantation: A Systematic Review. Nutrients. (2018) E729. inserm-01815356

Charlotte Roy, Julie Tabiasco, Antoine Caillon, Yves Delneste, Jean Mérot, Julie Favre, Anne-Laure Guihot, Ludovic Martin, Danielle C. Nascimento, Bernhard Ryffel, Simon Robson, Jean Sévigny, Daniel Henrion, Gilles Kauffenstein. Loss of vascular expression of nucleoside triphosphate diphosphohydrolase-1/CD39 in hypertension. Purinergic Signalling. (2018) 73-82. inserm-01738043

Raffaella Soleti, Gregory Hilairet, Patricia Mallegol, Catherine Dourguia, Mehdi Frifra, Marie Guillou, Agnes Gacel, Sylvain Guyot, Pascale Pignon, Laetitia Basset, Yves Cadot, Jean Renou, Mathilde Orsel, Ramaroson Andriantsitohaina. Screening of ordinary commercial varieties of apple fruits under different storage conditions for their potential vascular and metabolic protective properties. Food and Function. (2018) 5855-5867. inserm-01958474

Léa Paolini, Caroline Poli, Simon Blanchard, Thierry Urban, Anne Croué, Marie-Christine Rousselet, Sarah Le Roux, Nathalie Labarrière, Pascale Jeannin, José Hureaux. Thoracic and cutaneous sarcoid-like reaction associated with anti-PD-1 therapy: longitudinal monitoring of PD-1 and PD-L1 expression after stopping treatment. Journal for Immunotherapy of Cancer. (2018) 52. inserm-01817689

EQUIPE 8

Jennifer Allègre, Jessy Cartier, Valérie Glorian, Droin Nathalie, Baptiste Dumetier, Cémile Kayaci, Jean Berthelet, Simon Gemble, Céline Vuillier, Laurent Maillet, Carmen Garrido, Laurence Dubrez. E2F1 binds to the peptide-binding groove within the BIR3 domain of cIAP1 and requires cIAP1 for chromatin binding. PLoS ONE. (2018) e0206253. hal-01923499

Pascal Jézéquel, Mario Campone. Comment on “How the evolution of multicellularity set the stage for cancer”. British Journal of Cancer. (2018) Epub ahead of print. inserm-01823385

Lorenzo Galluzzi, Ilio Vitale, Stuart A. Aaronson, John M. Abrams, Dieter Adam, Patrizia Agostinis, Emad S. Alnemri, Lucia Altucci, Ivano Amelio, David W. Andrews, Margherita Annicchiarico-Petruzzelli, Alexey V. Antonov, Eli Arama, Eric H. Baehrecke, Nickolai A. Barlev, Nicolas G. Bazan, Francesca Bernassola, Mathieu J. M. Bertrand, Katiuscia Bianchi, Mikhail V. Blagosklonny, Klas Blomgren, Christoph Borner, Patricia Boya, Catherine Brenner, Michelangelo Campanella, Eleonora Candi, Didac Carmona-Gutierrez, Francesco Cecconi, Francis K.-M. Chan, Navdeep S. Chandel, Emily H. Cheng, Jerry E. Chipuk, John A. Cidlowski, Aaron Ciechanover, Gerald M. Cohen, Marcus Conrad, Juan R. Cubillos-Ruiz, Peter E. Czabotar, Vincenzo D Angiolella, Ted M. Dawson, Valina L. Dawson, Vincenzo De Laurenzi, Ruggero De Maria, Klaus-Michael Debatin, Ralph J. DeBerardinis, Mohanish Deshmukh, Nicola Di Daniele, Francesco Di Virgilio, Vishva M. Dixit, Scott J. Dixon, Colin S. Duckett, Brian D. Dynlacht, Wafik S. El-Deiry, John W. Elrod, Gian Maria Fimia, Simone Fulda, Ana J. García-Sáez, Abhishek D. Garg, Carmen Garrido, Evripidis Gavathiotis, Pierre Golstein, Eyal Gottlieb, Douglas R. Green, Lloyd A. Greene, Hinrich Gronemeyer, Atan Gross, Gyorgy Hajnoczky, J. Marie Hardwick, Isaac S. Harris, Michael O. Hengartner, Claudio Hetz, Hidenori Ichijo, Marja Jäättelä, Bertrand Joseph, Philipp J. Jost, Philippe P. Juin, William J. Kaiser, Michael Karin, Thomas Kaufmann, Oliver Kepp, Adi Kimchi, Richard N. Kitsis, Daniel J. Klionsky, Richard A. Knight, Sharad Kumar, Sam W. Lee, John J. Lemasters, Beth Levine, Andreas Linkermann, Stuart A. Lipton, Richard A. Lockshin, Carlos López-Otín, Scott W. Lowe, Tom Luedde, Enrico Lugli, Marion MacFarlane, Frank Madeo, Michal Malewicz, Walter Malorni, Gwenola Manic, Jean-Christophe Marine, Seamus J. Martin, Jean-Claude Martinou, Jan Paul Medema, Patrick Mehlen, Pascal Meier, Sonia Melino, Edward A. Miao, Jeffery D. Molkentin, Ute M. Moll, Cristina Muñoz-Pinedo, Shigekazu Nagata, Gabriel Nuñez, Andrew Oberst, Moshe Oren, Michael Overholtzer, Michele Pagano, Theocharis Panaretakis, Manolis Pasparakis, Josef M. Penninger, David M. Pereira, Shazib Pervaiz, Marcus E. Peter, Mauro Piacentini, Paolo Pinton, Jochen H.M. Prehn, Hamsa Puthalakath, Gabriel A. Rabinovich, Markus Rehm, Rosario Rizzuto, Cecilia M.P. Rodrigues, David C. Rubinsztein, Thomas Rudel, Kevin M. Ryan, Emre Sayan, Luca Scorrano, Feng Shao, Yufang Shi, John Silke, Hans-Uwe Simon, Antonella Sistigu, Brent R. Stockwell, Andreas Strasser, Gyorgy Szabadkai, Stephen W.G. Tait, Daolin Tang, Nektarios Tavernarakis, Andrew Thorburn, Yoshihide Tsujimoto, Boris Turk, Tom Vanden Berghe, Peter Vandenabeele, Matthew G. Vander Heiden, Andreas Villunger, Herbert W. Virgin, Karen H. Vousden, Domagoj Vucic, Erwin F. Wagner, Henning Walczak, David Wallach, Ying Wang, James A. Wells, Will Wood, Junying Yuan, Zahra Zakeri, Boris Zhivotovsky, Laurence Zitvogel, Gerry Melino, Guido Kroemer. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. (2018) 486–541. hal-01727577

Céline Vuillier, Steven Lohard, Aurélie Fétiveau, Jennifer Allègre, Cémile Kayaci, Louise King, Frédérique Braun, Sophie Barillé-Nion, Fabien Gautier, Laurence Dubrez, Andrew Gilmore, Philippe Juin, Laurent Maillet. E2F1 interacts with BCL‐xL and regulates its subcellular localization dynamics to trigger cell death. EMBO Reports. (2018) 234-243. inserm-01669957

Lazaro Aira, Elodie Villa, Pascal Colosetti, Parvati Gamas, Laurie Signetti, Sandrine Obba, Emma Proics, Fabien Gautier, Beatrice Bailly-Maitre, Arnaud Jacquel, Guillaume Robert, Frédéric Luciano, Philippe Juin, Jean-Ehrland Ricci, Patrick Auberger, Sandrine Marchetti. The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim. Oncogene. (2018) 2122 – 2136. inserm-01814383

Siham Hedir, Marcella De Giorgi, Jade Fogha, Martina De Pascale, Louis-Bastien Weiswald, Emilie Brotin, Bogdan Marekha, Christophe Denoyelle, Camille Denis, Peggy Suzanne, Fabien Gautier, Philippe Juin, Laetitia Ligat, Frédéric Lopez, Ludovic Carlier, Rémi Legay, Ronan Bureau, Sylvain Rault, Laurent Poulain, Jana Sopkova-de Oliveira Santos, Anne-Sophie Voisin-Chiret. Structure-guided design of pyridoclax derivatives based on Noxa / Mcl-1 interaction mode. European Journal of Medicinal Chemistry. (2018) 357-380. inserm-01980723

Marie Robert, Anne Patsouris, Jean-Sébastien Frenel, Carole Gourmelon, Paule Augereau, Mario Campone. Emerging PARP inhibitors for treating breast cancer. Expert Opinion on Emerging Drugs. (2018) 211-221. inserm-01977751

Anne Lok, Géraldine Descamps, Benoit Tessoulin, David Chiron, Marion Eveillard, Catherine Godon, Yannick Le Bris, Astrid Vabret, Céline Bellanger, Laurent Maillet, Sophie Barillé-Nion, Marc Gregoire, Jean-François Fonteneau, Steven Le Gouill, Philippe Moreau, Frederic Tangy, Martine Amiot, Agnès Moreau-Aubry, Catherine Pellat-Deceunynck. p53 regulates CD46 expression and measles virus infection in myeloma cells. Blood Advances. (2018) 3492-3505. inserm-01957487

EQUIPE 9

Jorge Vargas-Franco, Beatriz Castaneda, Françoise Rédini, David Francisco Gómez, Dominique Heymann, Frederic Lezot. Paradoxical side effects of bisphosphonates on the Skeleton : What do we know and what can we do ? Journal of Cellular Physiology. (2018) Epub ahead of print. inserm-01693313

Yolanda González-Fernández, Hannah Brown, Ana Patiño-García, Dominique Heymann, María Blanco-Prieto. Oral edelfosine lipid nanoparticles caused the regression of lung metastases in pre- clinical osteosarcoma animal models. Cancer Letters. (2018) 193 – 200. inserm-01803295

Marja Steenman, Olivier espetia, Blandine Maurel, Béatrice Guyomarch, Marie-Françoise Heymann, Marc-Antoine Pistorius, Benjamin Ory, Dominique Heymann, Rémi Houlgatte, Yann Gouëffic, Thibaut Quillard. Identification of genomic differences among peripheral arterial beds in atherosclerotic and healthy arteries. Scientific Reports. (2018) 3940. inserm-01725150

Daniëlle de Ridder, Silvia Marino, Ryan Bishop, Nathalie Renema, Chantal Chenu, Dominique Heymann, Aymen Idris. Bidirectional regulation of bone formation by exogenous and osteosarcoma-derived Sema3A. Scientific Reports. (2018) 6877. inserm-01792163

Delphine Garnier, Ruoya Li, Frédéric Delbos, Angélique Fourrier, Camille Collet, Christiane Guguen-Guillouzo, Christophe Chesné, Tuan Huy Nguyen. Expansion of human primary hepatocytes in vitro through their amplification as liver progenitors in a 3D organoid system. Scientific Reports. (2018) 8222 – 8222. inserm-01810195

Delphine Garnier, Brian Meehan, Thomas Kislinger, Paul Daniel, Ankit Sinha, Bassam Abdulkarim, Ichiro Nakano, Janusz Rak. Divergent evolution of temozolomide resistance in glioblastoma stem cells is reflected in extracellular vesicles and coupled with radiosensitization. Neuro-Oncology. (2018) 236 – 248. inserm-01814308

Benjamin Navet, Jorge Vargas-Franco, Andrea Gama, Jerome Amiaud, Yongwon Choi, Hideo Yagita, Christopher Mueller, Françoise Rédini, Dominique Heymann, Beatriz Castaneda, Frédéric Lézot. Maternal RANKL Reduces the Osteopetrotic Phenotype of Null Mutant Mouse Pups. Journal of Clinical Medicine Research. (2018) E426. inserm-01923428

The Milieu Intérieur Consortium, Stephanie Kilens, Dimitri Meistermann, Diego Moreno, Caroline Chariau, Anne Gaignerie, Arnaud Reignier, Yohann Lelièvre, Miguel Casanova, Céline Vallot, Steven Nedellec, Léa Flippe, Julie Firmin, Juan Song, Eric Charpentier, Jenna Lammers, Audrey Donnart, Nadège Marec, Wallid Deb, Audrey Bihouee, Cédric Le Caignec, Claire Pecqueur, Richard Redon, Paul Barriere, Jérémie Bourdon, Vincent Pasque, Magali Soumillon, Tarjei S Mikkelsen, Claire Rougeulle, Thomas Freour, Laurent David. Parallel derivation of isogenic human primed and naive induced pluripotent stem cells. Nature Communications. (2018) 487. hal-01881146

Camille Jacques, Nathalie Renema, Frédéric Lézot, Benjamin Ory, Carl Walkley, Agamemnon Grigoriadis, Dominique Heymann. Small animal models for the study of bone sarcoma pathogenesis:characteristics, therapeutic interests and limitations. Journal of Bone Oncology. (2018) 7-13. inserm-01814330

Antoine Chalopin, Marta Tellez-Gabriel, Hannah Brown, Francois Vallette, Marie Françoise Heymann, Dominique Heymann. Isolation of circulating tumor cells in a preclinical model of osteosarcoma: effect of chemotherapy. Journal of Bone Oncology. (2018) 83-90. inserm-01851614

Hannah Brown, Marta Tellez-Gabriel, Pierre-François Cartron, François Vallette, Marie-Françoise Heymann, Dominique Heymann. Characterization of circulating tumor cells as a reflection of the tumor heterogeneity: myth or reality? Drug Discovery Today Biosilico. (2018) Epub ahead of print. inserm-01947472

Eric Hervouet, Paul Peixoto, Régis Delage-Mourroux, Michaël Boyer-Guittaut, Pierre-François Cartron. Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma. Clinical Epigenetics. (2018) 17. inserm-01981717

Josephine Briand, Arulraj Nadaradjane, François Vallette, Pierre Cartron. The TET2 Expression Level Correlates with a Short Relapse Time in Glioblastoma Multiforme. Journal of Clinical Epigenetics / J Clin Epigenet. (2018) 12. inserm-01981842

Marta Tellez-Gabriel, Denis Cochonneau, Marie Cadé, Camille Jubelin, Marie-Françoise Heymann, Dominique Heymann. Circulating Tumor Cell-Derived Pre-Clinical Models for Personalized Medicine. Cancers. (2018) epub ahead of print. inserm-01964962

Steven Georges, Lidia Calleja, Camille Jacques, Melanie Lavaud, Brice Moukengue, Fernando Lecanda, Thibaut Quillard, Marta Gabriel, Pierre-François Cartron, Marc Baudéposhuin, François Lamoureux, Dominique Heymann, Benjamin Ory. Loss of miR-198 and-206 during primary tumor progression enables metastatic dissemination in human osteosarcoma. Oncotarget. (2018) 35726 – 35741. inserm-01982044

Arulraj Nadaradjane, Joséphine Briand, Gwenola Bougras-Cartron, Valentine Disdero, François Vallette, Jean-Sébastien Frenel, Pierre-François Cartron. miR-370-3p Is a Therapeutic Tool in Anti-glioblastoma Therapy but Is Not an Intratumoral or Cell-free Circulating Biomarker. Molecular Therapy – Nucleic Acids. (2018) 642-650. inserm-01982015

Catherine Boisson-Vidal, Zahia Benslimane-Ahmim, Anna Lokajczyk, Dominique Heymann, David Smadja. Osteoprotegerin induces CD34 + differentiation in Endothelial Progenitor Cells. Frontiers in Medicine. (2018) 331. inserm-01965981

François Vallette, Christophe Olivier, Frederic Lezot, Lisa Oliver, Denis Cochonneau, Lisenn Lalier, François Cartron, Dominique Heymann. Dormant, quiescent, tolerant and persister cells: Four synonyms for the same target in cancer. Biochemical Pharmacology. (2018) Epub ahead of print. inserm-01947474

Stéphanie Kilens, Dimitri Meistermann, Diego Moreno, Caroline Chariau, Anne Gaignerie, Arnaud Reignier, Yohann Lelièvre, Miguel Casanova, Céline Vallot, Steven Nedellec, Léa Flippe, Julie Firmin, Juan Song, Eric Charpentier, Jenna Lammers, Audrey Donnart, Nadège Marec, Wallid Deb, Audrey Bihouée, Cédric Le Caignec, Claire Pecqueur, Richard Redon, Paul Barriere, Jérémie Bourdon, Vincent Pasque, Magali Soumillon, Tarjei Mikkelsen, Claire Rougeulle, Thomas Freour, Laurent David, Milieu Intérieur Consortium. Parallel derivation of isogenic human primed and naive induced pluripotent stem cells. Nature Communications. (2018) 302 – 314. pasteur-01758726

Noémie Joalland, Cynthia Chauvin, Lisa Oliver, François Vallette, Claire Pecqueur, Ulrich Jarry, Emmanuel Scotet. IL-21 Increases the Reactivity of Allogeneic Human Vγ9Vδ2 T Cells Against Primary Glioblastoma Tumors. Journal of immunotherapy : official journal of the Society for Biological Therapy. (2018) 224-231. inserm-01804994

Ulrich Jarry, Noémie Joalland, Cynthia Chauvin, Beatrice Clemenceau, Claire Pecqueur, Emmanuel Scotet. Stereotactic Adoptive Transfer of Cytotoxic Immune Cells in Murine Models of Orthotopic Human Glioblastoma Multiforme Xenografts. Journal of visualized experiments : JoVE. (2018) 1(139). inserm-01885088

Christophe Blanquart, Camille Linot, Pierre-François Cartron, Daniela Tomaselli, Antonello Mai, Philippe Bertrand. Epigenetic metalloenzymes. Current Medicinal Chemistry. (2018) 1-36. inserm-01885512

EQUIPE 10

Yassine Al Tabaa, Emmanuel Tchernonog, Pierre Faurie, Anne Ségolène Cottereau, Hélène Monjanel, Antoine Bonnet, Steven Le Gouill, Emmanuel Gyan, Hervé Ghesquières, Denis Mariano-Goulart, Guillaume Cartron. Post-treatment positron emission tomography-computed tomography is highly predictive of outcome in Plasmablastic lymphoma. European Journal of Nuclear Medicine and Molecular Imaging. (2018) 1705-1709. hal-01833550

Patrick Casara, James Davidson, Audrey Claperon, Gaëtane Le Toumelin-Braizat, Meike Vogler, Alain Bruno, Maïa Chanrion, Gaëlle Lysiak-Auvity, Thierry Le Diguarher, Jérôme-Benoît Starck, Ijen Chen, Neil Whitehead, Christopher Graham, Natalia Matassova, Pawel Dokurno, Christopher Pedder, Youzhen Wang, Shumei Qiu, Anne-Marie Girard, Emilie Schneider, Fabienne Gravé, Aurélie Studeny, Ghislaine Guasconi, Francesca Rocchetti, Sophie Maïga, Jean-Michel Henlin, Frédéric Colland, Laurence Kraus-Berthier, Steven Le Gouill, Martin Dyer, Roderick Hubbard, Mike Wood, Martine Amiot, Gerald Cohen, John Hickman, Erick Morris, James Murray, Olivier Geneste. S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth. Oncotarget. (2018) 20075 – 20088. inserm-01807731

Roch Houot, G Cartron, Fontanet Bijou, Sophie De Guibert, Gilles A. Salles, Christophe Fruchart, Krimo Bouabdallah, Marie Maerevoet, Pierre Feugier, Steven Le Gouill, Hervé Tilly, Rene-Olivier Casasnovas, Cécile Moluçon-Chabrot, Eric Van Den Neste, Pierre Zachee, Marc Andre, Christophe Bonnet, Corinne Haioun, Achiel Van Hoof, Koen Van Eygen, Lysiane Molina, Emmanuelle Nicolas-Virelizier, Philippe Ruminy, Franck Morschhauseur. Obinutuzumab plus Lenalidomide (GALEN) for the treatment of relapse/refractory aggressive lymphoma: a phase II LYSA study. Leukemia. (2018) 776-780. inserm-01934613

Alix Augustin, Steven Le Gouill, Remy Gressin, Aurélie Bertaut, Alain Monnereau, Anne Woronoff, Brigitte Tretarre, Patricia Delafosse, Xavier Troussard, Anne Moreau, Olivier Hermine, Marc Maynadié. Survival benefit of mantle cell lymphoma patients enrolled in clinical trials; a joint study from the LYSA group and French cancer registries. Journal of Cancer Research and Clinical Oncology. (2018) 629–635. inserm-01624838

Franck Morschhauser, Nathan Fowler, Pierre Feugier, Reda Bouabdallah, Hervé Tilly, M Palomba, Christophe Fruchart, Edward Libby, René-Olivier Casasnovas, Ian Flinn, Corinne Haioun, Hervé Maisonneuve, Loic Ysebaert, Nancy Bartlett, Kamal Bouabdallah, Pauline Brice, Vincent Ribrag, Nicolas Daguindau, Steven Le Gouill, Gian Pica, Alejandro Martin Garcia-Sancho, Armando Lopez-Guillermo, Jean-François Larouche, Kiyoshi Ando, Maria Gomes da Silva, Marc André, Pierre Zachee, Laurie Sehn, Kensei Tobinai, Guillaume Cartron, David Liu, Jianming Wang, Luc Xerri, Gilles Salles. Rituximab plus Lenalidomide in Advanced Untreated Follicular Lymphoma. New England Journal of Medicine. (2018) 934 – 947. inserm-01934589

Thierry Lamy, Gandhi Damaj, Pierre Soubeyran, Emmanuel Gyan, Guillaume Cartron, Krimo Bouabdallah, Rémy Gressin, Jérôme Cornillon, Anne Banos, Katell Le Du, Mohamed Benchalal, Marie-Pierre Moles, Steven Le Gouill, Joel Fleury, Pascal Godmer, Hervé Maisonneuve, Eric Deconinck, Roch Houot, Kamel Laribi, Jean Pierre Marolleau, Olivier Tournilhac, Bernard Branger, Anne Devillers, Philippe Vuilliez, Thierry Fest, Philippe Colombat, Valérie Costes, Vanessa Szablewski, Marie C. Béné, Vincent Delwail. R-CHOP 14 with or without radiotherapy in non-bulky limited-stage diffuse large B-cell lymphoma (DLBCL). Blood. (2018) 174-181. hal-01635792

Michael Wang, Simon Rule, Pier Zinzani, Andre Goy, Olivier Casasnovas, Stephen Smith, Gandhi Damaj, Jeanette Doorduijn, Thierry Lamy, Franck Morschhauser, Carlos Panizo, Bijal Shah, Andrew Davies, Richard Eek, Jehan Dupuis, Eric Jacobsen, Arnon Kater, Steven Le Gouill, Lucie Oberic, Taduesz Robak, Todd Covey, Richa Dua, Ahmed Hamdy, xin huang, Raquel Izumi, Priti Patel, Wayne Rothbaum, Greg Slatter, Wojciech Jurczak. Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial. Lancet. (2018) 659-667. inserm-01980627

Patricia Gomez-Bougie, Sophie Maïga, Benoit Tessoulin, Jessie Bourcier, Antoine Bonnet, Manuel Rodriguez, Steven Le Gouill, Cyrille Touzeau, Philippe Moreau, Catherine Pellat-Deceunynck, Martine Amiot. BH3-mimetic toolkit guides the respective use of BCL2 and MCL1 BH3-mimetics in myeloma treatment. Blood. (2018) Epub ahead of print. inserm-01900681

Cyrille Touzeau, Paulo Maciag, Martine Amiot, Philippe Moreau. Targeting Bcl-2 for the treatment of multiple myeloma. Leukemia. (2018) 1899 – 1907. inserm-01885190

Cyrille Touzeau, Philippe Moreau. Ixazomib in the management of relapsed multiple myeloma. Future Oncology. (2018) 2013 – 2020. inserm-01934497

Benoit Tessoulin, Agnès Moreau-Aubry, Géraldine Descamps, Patricia Gomez-Bougie, Sophie Maiga, Alban Gaignard, David Chiron, Emmanuelle Ménoret, Steven Le Gouill, Philippe Moreau, Martine Amiot, Catherine Pellat-Deceunynck. Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways. Journal of Hematology & Oncology. (2018) 137. inserm-01958772

Anne Lok, Géraldine Descamps, Benoit Tessoulin, David Chiron, Marion Eveillard, Catherine Godon, Yannick Le Bris, Astrid Vabret, Céline Bellanger, Laurent Maillet, Sophie Barillé-Nion, Marc Gregoire, Jean-François Fonteneau, Steven Le Gouill, Philippe Moreau, Frederic Tangy, Martine Amiot, Agnès Moreau-Aubry, Catherine Pellat-Deceunynck. p53 regulates CD46 expression and measles virus infection in myeloma cells. Blood Advances. (2018) 3492-3505. inserm-01957487

Pierre Sujobert, Yannick Le Bris, Laurence De Leval, Audrey Gros, Jean Philippe Merlio, Cedric Pastoret, Sarah Huet, Clémentine Sarkozy, Frederic Davi, Mary Callanan, Catherine Thieblemont, David Sibon, Vahid Asnafi, Claude Preudhomme, Philippe Gaulard, Fabrice Jardin, Gilles Salles, Elizabeth Macintyre. Definition of a minimal genes set for mature lymphoid blood diseases. Hématologie. (2018) 27-59. hal-01870189

Pierre Peterlin, Joëlle Gaschet, Thierry Guillaume, Alice Garnier, Marion Eveillard, Amandine Le Bourgeois, Michel Chérel, Camille Debord, Yannick Le Bris, Olivier Theisen, Béatrice Mahé, Viviane Dubruille, Soraya Wuilleme, Catherine Godon, Cyrille Touzeau, Thomas Gastinne, Nicolas Blin, Anne Lok, Antoine Bonnet, Steven Le Gouill, Philippe Moreau, Marie Béné, Patrice Chevallier. Fms-like Tyrosine Kinase 3 Ligand Concentration Kinetic Profile during Induction Is Strongly Predictive of Survivals in AML: Results of the FLAM/Flal Study. Blood (2018) 1484. inserm-02341909

EQUIPE 11

Niccolò Bolli, Francesco Maura, Stéphane Minvielle, Dominik Gloznik, Raphael Szalat, Anthony Fullam, Inigo Martincorena, Kevin Dawson, Mehmet Samur, Jorge Zamora, Patrick Tarpey, Helen Davies, Mariateresa Fulciniti, Masood Shammas, Yu-Tzu Tai, Florence Magrangeas, Philippe Moreau, Paolo Corradini, Kenneth Anderson, Ludmil Alexandrov, David Wedge, Hervé Avet-Loiseau, Peter Campbell, Nikhil Munshi. Genomic patterns of progression in smoldering multiple myeloma. Nature Communications. (2018) 3363. inserm-01885513

Lydie Debaize, Hélène Jakobczyk, Stéphane Avner, Jérémie Gaudichon, Anne-Gäelle Rio, Aurélien Sérandour, Lena Dorsheimer, Frédéric Chalmel, Jason Carroll, Martin Zornig, Michael Rieger, Olivier Delalande, Gilles Salbert, Marie-Dominique Galibert, Virginie Gandemer, Marie-Bérengère Troadec. Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation. Nucleic Acids Research. (2018) 11214-11228. inserm-01885128

Bertrand Miannay, Stéphane Minvielle, Florence Magrangeas, Carito Guziolowski. Constraints on signaling network logic reveal functional subgraphs on Multiple Myeloma OMIC data. BMC Systems Biology. (2018) 32 – 32. inserm-01804825

Aurelien Serandour, Hisham Mohammed, Ahmad Miremadi, Klaas Mulder, Jason Carroll. TRPS1 regulates oestrogen receptor binding and histone acetylation at enhancers. Oncogene. (2018) 5281-5291. inserm-01814235

Eric Voog, Loïc Campion, Pauline du Rusquec, Hugues Bourgeois, Julien Domont, Fabrice Denis, Eric Emmanuel, Olivier Dupuis, Gérard Ganem, Cedrik Lafont, Katell Le Du, Elena Pavluc, Yohan Pointreau, Sophie Roche, Laurence Juhel-Voog, Marie Zinger, Philippe Solal-Celigny. Totally implantable venous access ports: a prospective long-term study of early and late complications in adult patients with cancer. Supportive Care in Cancer. (2018) 81-89. inserm-01819309

Mehmet Kemal Samur, Stéphane Minvielle, Annamaria Gulla, Mariateresa Fulciniti, Alice Cleynen, Anil Samur, Raphael Szalat, Masood Shammas, Florence Magrangeas, Yu-Tzu Tai, Daniel Auclair, Jonathan Keats, Paul Richardson, Michel Attal, Philippe Moreau, Kenneth Anderson, Giovanni Parmigiani, Hervé Avet-Loiseau, Nikhil Munshi. Long intergenic non-coding RNAs have an independent impact on survival in multiple myeloma. Leukemia. (2018) Epub ahead of print. inserm-01804867

Lokmane Chebouba, Bertrand Miannay, Dalila Boughaci, Carito Guziolowski. Discriminate the response of Acute Myeloid Leukemia patients to treatment by using proteomics data and Answer Set Programming. BMC Bioinformatics. (2018) S2. hal-01988426

Patricia Gomez-Bougie, Sophie Maïga, Benoit Tessoulin, Jessie Bourcier, Antoine Bonnet, Manuel Rodriguez, Steven Le Gouill, Cyrille Touzeau, Philippe Moreau, Catherine Pellat-Deceunynck, Martine Amiot. BH3-mimetic toolkit guides the respective use of BCL2 and MCL1 BH3-mimetics in myeloma treatment. Blood. (2018) Epub ahead of print. inserm-01900681

Cyrille Touzeau, Paulo Maciag, Martine Amiot, Philippe Moreau. Targeting Bcl-2 for the treatment of multiple myeloma. Leukemia. (2018) 1899 – 1907. inserm-01885190

Cyrille Touzeau, Philippe Moreau. Ixazomib in the management of relapsed multiple myeloma. Future Oncology. (2018) 2013 – 2020. inserm-01934497

Benoit Tessoulin, Agnès Moreau-Aubry, Géraldine Descamps, Patricia Gomez-Bougie, Sophie Maiga, Alban Gaignard, David Chiron, Emmanuelle Ménoret, Steven Le Gouill, Philippe Moreau, Martine Amiot, Catherine Pellat-Deceunynck. Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways. Journal of Hematology & Oncology. (2018) 137. inserm-01958772

Anne Lok, Géraldine Descamps, Benoit Tessoulin, David Chiron, Marion Eveillard, Catherine Godon, Yannick Le Bris, Astrid Vabret, Céline Bellanger, Laurent Maillet, Sophie Barillé-Nion, Marc Gregoire, Jean-François Fonteneau, Steven Le Gouill, Philippe Moreau, Frederic Tangy, Martine Amiot, Agnès Moreau-Aubry, Catherine Pellat-Deceunynck. p53 regulates CD46 expression and measles virus infection in myeloma cells. Blood Advances. (2018) 3492-3505. inserm-01957487

Loig Vaugier, Clément Palpacuer, Emmanuel Rio, Aurore Goineau, David Pasquier, Xavier Buthaud, Guy De Laroche, Véronique Beckendorf, Paul Sargos, Gilles Créhange, Pascal Pommier, Geneviève Loos, Ali Hasbini, Igor Latorzeff, Marlon Silva, Fabrice Denis, Jean-Léon Lagrange, Loïc Campion, Stéphane Supiot. Early toxicity of a phase II trial of combined salvage radiotherapy and hormone therapy in oligometastatic pelvic node relapses of prostate cancer (OLIGOPELVIS GETUG P07). International Journal of Radiation Oncology, Biology, Physics. (2018) 1061-1067. inserm-01980788

Vincent Fleury, Ludovic Ferrer, Mathilde Colombié, Daniela Rusu, Maëlle Le Thiec, Françoise Kraeber-Bodéré, Loïc Campion, Caroline Rousseau. Advantages of systematic trunk SPECT/CT to planar bone scan (PBS) in more than 300 patients with breast or prostate cancer. Oncotarget. (2018) 31744-31752. inserm-01885515

Stéphane Supiot, Caroline Rousseau, Mélanie Dore, Catherine Cheze-Le-Rest, Christine Kandel-Aznar, Vincent Potiron, Stéphane Guerif, François Paris, Ludovic Ferrer, Loïc Campion, Philippe Meingan, Grégory Delpon, Mathieu Hatt, Dimitris Visvikis. Evaluation of tumor hypoxia prior to radiotherapy in intermediate-risk prostate cancer using [18]F-fluoromisonidazole PET/CT: a pilot study. Oncotarget. (2018) 10005 – 10015. inserm-01823478

Aurelien A. Serandour, Stéphane Avner, Gilles Salbert. Coupling Exonuclease Digestion with Selective Chemical Labeling for Base-resolution Mapping of 5-Hydroxymethylcytosine in Genomic DNA. Bio-Protocol. (2018) 8;5. hal-02062038

Pierre Peterlin, Joëlle Gaschet, Thierry Guillaume, Alice Garnier, Marion Eveillard, Amandine Le Bourgeois, Michel Chérel, Camille Debord, Yannick Le Bris, Olivier Theisen, Béatrice Mahé, Viviane Dubruille, Soraya Wuilleme, Catherine Godon, Cyrille Touzeau, Thomas Gastinne, Nicolas Blin, Anne Lok, Antoine Bonnet, Steven Le Gouill, Philippe Moreau, Marie Béné, Patrice Chevallier. Fms-like Tyrosine Kinase 3 Ligand Concentration Kinetic Profile during Induction Is Strongly Predictive of Survivals in AML: Results of the FLAM/Flal Study. Blood (2018) 1484. inserm-02341909

EQUIPE 12

Mélanie Le Duff, Julien Gouju, Barbara Jonchère, Jordan Guillon, Bertrand Toutain, Alice Boissard, Cécile Henry, Catherine Guette, Eric Lelievre, Olivier Coqueret. Regulation of senescence escape by the cdk4–EZH2–AP2M1 pathway in response to chemotherapy. Cell Death and Disease. (2018) 199. inserm-01718563

Joëlle Nader, Jérôme Abadie, Sophie Deshayes, Alice Boissard, Stéphanie Blandin, Christophe Blanquart, Nicolas Boisgerault, Olivier Coqueret, Catherine Guette, Marc Grégoire, Daniel Pouliquen. Characterization of increasing stages of invasiveness identifies stromal/cancer cell crosstalk in rat models of mesothelioma. Oncotarget. (2018) Epub ahead of print. inserm-01726393

EQUIPE 13

Thomas Le Bihan, Anne-Sophie Navarro, Nathalie Le Bris, Patricia Le Saec, Sébastien Gouard, Ferid Haddad, Jean-François Gestin, Michel Cherel, Alain Faivre-Chauvet, Raphaël Tripier. Synthesis of C-functionalized TE1PA and comparison with its analogues. An example of bioconjugation on 9E7.4 mAb for multiple myeloma 64 Cu-PET imaging. Organic and Biomolecular Chemistry. (2018) Epub ahead of print. inserm-01804657

Clément Bailly, Sébastien Gouard, Marie Lacombe, Patricia Remaud-Le Saëc, Benjamin Chalopin, Mickael Bourgeois, Nicolas Chouin, Raphaël Tripier, Zakaria Halime, Ferid Haddad, Alain Faivre-Chauvet, Françoise Kraeber-Bodéré, Michel Chérel, Caroline Bodet-Milin. Comparison of Immuno-PET of CD138 and PET imaging with 64CuCl2 and 18F-FDG in a preclinical syngeneic model of multiple myeloma. Oncotarget. (2018). hal-01677118

Thibaut Merlin, Simon Stute, Didier Benoit, Julien Bert, Thomas Carlier, Claude Comtat, Marina Filipovic, Frédéric Lamare, Dimitris Visvikis. CASToR: a generic data organization and processing code framework for multi-modal and multi-dimensional tomographic reconstruction. Physics in Medicine and Biology. (2018) 185005. hal-01935073

Marie Guillou, Blandine Maurel, Hatem Necib, Pierre-Alexandre Vent, Alain Costargent, Philippe Chaillou, Yann Gouëffic, Adrien Kaladji. Comparison of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease with Flat-Panel Detectors on Mobile C-arm versus Fixed Systems. Annals of Vascular Surgery. (2018) 104-113. hal-01713546

Clément Bailly, Thomas Carlier, Bastien Jamet, Thomas Eugène, Cyrille Touzeau, Michel Attal, Cyrille Hulin, Thierry Facon, Xavier Leleu, Aurore Perrot, Laurent Garderet, Margaret Macro, Denis Caillot, Philippe Moreau, Francoise Kraeber-Bodere, Caroline Bodet-Milin. Interim PET Analysis in First-Line Therapy of Multiple Myeloma: Prognostic Value of ΔSUVmax in the FDG-Avid Patients of the IMAJEM Study. Clinical Cancer Research. (2018) 5219 – 5224. inserm-01934540

Emmanuel Deshayes, Riad Ladjohounlou, Pierre Le Fur, Alexandre Pichard, Catherine Lozza, Vincent Boudousq, Samuel Sevestre, Marta Jarlier, Roxana Kashani, Joanna Koch, Jane Sosabowski, Julie Foster, Nicolas Chouin, Frank Bruchertseifer, Alfred Morgenstern, Pierre-Olivier Kotzki, Isabelle Navarro-Teulon, Jean-Pierre Pouget. Radiolabeled Antibodies Against Müllerian-Inhibiting Substance Receptor, Type II: New Tools for a Theranostic Approach in Ovarian Cancer. Journal of Nuclear Medicine. (2018) 1234 – 1242. inserm-01885063

Bart Cornelissen, James Knight, Somnath Mukherjee, Laura Evangelista, Catarina Xavier, Federico Caobelli, Silvana Del Vecchio, Latifa Rbah-Vidal, Jacques Barbet, Marion de Jong, Fijs van Leeuwen. Translational molecular imaging in exocrine pancreatic cancer. European Journal of Nuclear Medicine and Molecular Imaging. (2018) Epub ahead of print. inserm-01885212

Jean-François Chatal, Françoise Kraeber-Bodéré, Michel Chérel, Ferid Haddad. Alphatherapy, the new impetus to targeted radionuclide therapy? European Journal of Nuclear Medicine and Molecular Imaging. (2018) Epub ahead of print. inserm-01804899

Glenn Flux, K. Gleisner, C. Chiesa, M. Lassmann, Nicolas Chouin, J. Gear, M. Bardiès, S. Walrand, K. Bacher, U. Eberlein, M. Ljungberg, L. Strigari, E. Visser, M. W. Konijnenberg. From fixed activities to personalized treatments in radionuclide therapy: lost in translation? European Journal of Nuclear Medicine and Molecular Imaging. (2018) 152-154. inserm-01813923

Sandrine Huclier-Markai, Cyrille Alliot, Rabha Kerdjoudj, Marie Mougin-Degraef, Nicolas Chouin, Ferid Haddad. Promising Scandium Radionuclides for Nuclear Medicine: A Review on the Production and Chemistry up to In Vivo Proofs of Concept. Cancer Biotherapy and Radiopharmaceuticals. (2018) 316 – 329. inserm-01900722

Olivier Grémy, Laurent Miccoli, Faustine Lelan, Sandra Bohand, Michel Cherel, Marie Mougin-Degraef. Delivery of DTPA through Liposomes as a Good Strategy for Enhancing Plutonium Decorporation Regardless of Treatment Regimen. Radiation Research. (2018) 477 – 489. inserm-01804916

Sandrine Huclier-Markai, Alicia Grivaud-Le Du, Estelle N’tsiba, Gilles Montavon, Marie Mougin-Degraef, Jacques Barbet. Coupling a gamma-ray detector with asymmetrical flow field flow fractionation (AF4): Application to a drug-delivery system for alpha-therapy. Journal of Chromatography A. (2018) 107 – 114. inserm-01900710

Fanny Foubert, Sebastien Gouard, Catherine Sai-Maurel, Michel Cherel, Alain Faivre-Chauvet, David Goldenberg, Jacques Barbet, Clément Bailly, Caroline Bodet-Milin, Thomas Carlier, Françoise Kraeber-Bodéré, Yann Touchefeu, Eric Frampas. Sensitivity of pretargeted immunoPET using 68 Ga-peptide to detect colonic carcinoma liver metastases in a murine xenograft model: Comparison with 18 FDG PET-CT. Oncotarget. (2018) 27502 – 27513. inserm-01981491

Maël Millardet, Saïd Moussaoui, Diana Mateus, Jérôme Idier, Thomas Carlier. Local-mean preserving post-processing for non-negativity enforcement in 90Y-PET imaging. [Poster]. (2018). hal-01951847

Maël Millardet, Saïd Moussaoui, Diana Mateus, Jérôme Idier, Maurizio Conti, Thomas Carlier. A comparative study of AML, NEGML and OSEM based on experimental and clinical 90Y-PET data using the CASToR platform. [Poster]. (2018). hal-01953013

Maël Millardet, Saïd Moussaoui, Diana Mateus, Jérôme Idier, Thomas Carlier. Étude comparative d’AML, NEGML et OSEM sur des données 90Y-TEP expérimentales et cliniques en utilisant CASToR. [Poster]. (2018). hal-01953061

François Guérard. Propriétés et applications de l’astate en médecine nucléaire. Les Techniques de l’Ingenieur. (2018) nc. inserm-01960094

Mathieu Gauthé, Cyrielle Aveline, Frédéric Lecouvet, Laure Michaud, Caroline Rousseau, Marc Tassart, Olivier Cussenot, Jean-Noël Talbot, Isabelle Durand-Zaleski. Impact of sodium 18F-fluoride PET/CT, 18F-fluorocholine PET/CT and whole-body diffusion-weighted MRI on the management of patients with prostate cancer suspicious for metastasis: a prospective multicentre study. World Journal of Urology. (2018) Epub ahead of print. inserm-01981537

Avichai Shimoni, Myriam Labopin, Bipin Savani, Rose-Marie Hamladji, Dietrich Beelen, Ghulam Mufti, Gerard Socie, Jeremy Delage, Didier Blaise, Patrice Chevallier, Edouard Forcade, Eric Deconinck, Mohamad Mohty, Arnon Nagler. Intravenous Busulfan Compared with Treosulfan-Based Conditioning for Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia: A Study on Behalf of the Acute Leukemia Working Party of European Society for Blood and Marrow Transplantation. Biology of Blood and Marrow Transplantation. (2018) 751-757. hal-02143555

Vincent Fleury, Ludovic Ferrer, Mathilde Colombié, Daniela Rusu, Maëlle Le Thiec, Françoise Kraeber-Bodéré, Loïc Campion, Caroline Rousseau. Advantages of systematic trunk SPECT/CT to planar bone scan (PBS) in more than 300 patients with breast or prostate cancer. Oncotarget. (2018) 31744-31752. inserm-01885515

Stanimir Kambarev, Frédéric Pecorari, Stéphane Corvec. Novel Tn916-like elements confer aminoglycoside/macrolide co-resistance in clinical isolates of Streptococcus gallolyticus ssp. gallolyticus. Journal of Antimicrobial Chemotherapy. (2018) 1201 – 1205. inserm-01813206

Stéphane Supiot, Caroline Rousseau, Mélanie Dore, Catherine Cheze-Le-Rest, Christine Kandel-Aznar, Vincent Potiron, Stéphane Guerif, François Paris, Ludovic Ferrer, Loïc Campion, Philippe Meingan, Grégory Delpon, Mathieu Hatt, Dimitris Visvikis. Evaluation of tumor hypoxia prior to radiotherapy in intermediate-risk prostate cancer using [18]F-fluoromisonidazole PET/CT: a pilot study. Oncotarget. (2018) 10005 – 10015. inserm-01823478

Valentina Kalichuk, Stanimir Kambarev, Ghislaine Béhar, Benjamin Chalopin, Axelle Renodon-Cornière, Barbara Mouratou, Frédéric Pecorari. Affitins: Ribosome Display for Selection of Aho7c-Based Affinity Proteins. [in] Genotype Phenotype Coupling (2018) 19-41. inserm-02337107

Jean-Baptiste Gorin, Jérémie Ménager, Yannick Guilloux, Jean-François Chatal, Joëlle Gaschet, Michel Cherel. Combining RAIT and immune-based therapies to overcome resistance in cancer? Combining RAIT and immune-based therapies to overcome resistance in cancer? [in] Resistance to Ibritumomab in Lymphoma (2018). inserm-02338494

Clément Bailly, Caroline Bodet-Milin, François Guérard, Caroline Rousseau, Michel Chérel, Francoise Kraeber-Bodere, Jean-François Chatal. Prospects for Enhancing Efficacy of Radioimmunotherapy [in] Resistance to Ibritumomab in Lymphoma (2018). inserm-02315459

Clément Bailly, Sébastien Gouard, Benjamin Chalopin, Thomas Carlier, Catherine Sai-Maurel, Patricia Remaud-Le Saec, Mickaël Bourgeois, Nicolas Chouin, Raphaël Tripier, Ferid Haddad, Alain Faivre-Chauvet, Françoise Kraeber-Bodéré, Bodet-Milin Caroline, Michel Chérel. PET Imaging of Multiple Myeloma : Comparison of 89Zr- and 64Cu-labeled anti-CD138 Conjugates to 64CuCl2 and 18F-FDG in a Preclinical Syngeneic Model. European Journal of Nuclear Medicine and Molecular Imaging (2018) S20. inserm-02341452

Sébastien Gouard, Benjamin Chalopin, Catherine Saï-Maurel, François Guérard, Laurent Navarro, Jean-François Gestin, Nicolas Chouin, Ferid Haddad, Cyrille Alliot, Françoise Kraeber-Bodéré, François Davodeau, Michel Chérel. Efficacy of Astatine-211 radioimmunotherapy of Multiple Myeloma using an anti-mCD138 monoclonal antibody in a syngeneic murine model. European Journal of Nuclear Medicine and Molecular Imaging (2018) S167. inserm-02341491

Caroline Rousseau, Maëlle Le Thiec, Ludovic Ferrer, D. Rusu, A. Rauscher, B. Maucherat, Mathieu Frindel, P. Baumgartner, V. Fleury, A. Denis, N. Varmenot, E. Debeaupuis, Loïc Campion, Françoise Kraeber-Bodéré. Preliminary results of 68Ga-PSMA PET/CT prospective study in prostate cancer occult recurrence patients : diagnostic performance and impact on therapeutic decision-making. European Journal of Nuclear Medicine and Molecular Imaging (2018) S21. inserm-02341820

Elena Zamagni, Cristina Nanni, Luca Dozza, Thomas Carlier, Paola Tacchetti, Annibale Versari, Stephane Chauvie, Andrea Gallamini, Michel Attal, Barbara Gamberi, Denis Caillot, Francesca Patriarca, Margaret Macro, Mario Boccadoro, Laurent Garderet, Stefano Fanti, Aurore Perrot, Francesca Gay, Pieter Sonneveld, Lionel Karlin, Michele Cavo, Caroline Bodet-Milin, Philippe Moreau, Françoise Kraeber-Bodere. Standardization of 18F-FDG PET/CT According to Deauville Criteria for MRD Evaluation in Newly Diagnosed Transplant Eligible Multiple Myeloma Patients: Joined Analysis of Two Prospective Randomized Phase III Trials. Blood (2018) 257. inserm-02341857

Pierre Peterlin, Joëlle Gaschet, Thierry Guillaume, Alice Garnier, Marion Eveillard, Amandine Le Bourgeois, Michel Chérel, Camille Debord, Yannick Le Bris, Olivier Theisen, Béatrice Mahé, Viviane Dubruille, Soraya Wuilleme, Catherine Godon, Cyrille Touzeau, Thomas Gastinne, Nicolas Blin, Anne Lok, Antoine Bonnet, Steven Le Gouill, Philippe Moreau, Marie Béné, Patrice Chevallier. Fms-like Tyrosine Kinase 3 Ligand Concentration Kinetic Profile during Induction Is Strongly Predictive of Survivals in AML: Results of the FLAM/Flal Study. Blood (2018) 1484. inserm-02341909

A. Navarro, T. Le Bihan, Patricia Remaud-Le Saëc, Sébastien Gouard, N. Le Bris, Clément Bailly, Catherine Saï-Maurel, Benjamin Chalopin, Jean-François Gestin, Michel Chérel, R. Tripier, Alain Faivre-Chauvet. Biodistribution, Imaging and Metabolism Studies of 64-Copper Radiolabelled Monoclonal Antibody : Comparison of DOTA and TE1PA Chelating Agents in a Murine Model of Multiple Myeloma. European Journal of Nuclear Medicine and Molecular Imaging (2018) S119. inserm-02344286

A. Testard, M. Le Thiec, Ludovic Ferrer, C. Guillerminet, O. Morel, Françoise Kraeber-Bodéré, Caroline Rousseau. PET Pronostic Biomarkers Exploratory Analyses About Initial FDG-PET In Patients With Anal Carcinoma. European Journal of Nuclear Medicine and Molecular Imaging (2018) S466. inserm-02344311

Nicolas Varmenot, Ludovic Ferrer, M. Frindel, A. Rauscher, P. Baumgartner, F. Delaunay, A. Mathey, C. Pitel, H. Zulian, Françoise Kraeber-Bodéré, A. Denis, Caroline Rousseau. Why should we take care about occupational dosimetric impact when routine use of gallium-68 in nuclear medicine ? A preliminary study. European Journal of Nuclear Medicine and Molecular Imaging (2018) S81. inserm-02344327

EQUIPE 14

Olivier Guipaud, Cyprien Jaillet, Karen Clément-Colmou, Agnès François, Stéphane Supiot, Fabien Milliat. The importance of the vascular endothelial barrier in the immune-inflammatory response induced by radiotherapy. British Journal of Radiology. (2018) Epub ahead of print. inserm-01782208

Caroline Noblet, Grégory Delpon, Stéphane Supiot, Vincent Potiron, Francois Paris, Sophie Chiavassa. A new tissue segmentation method to calculate 3D dose in small animal radiation therapy. Radiation Oncology. (2018) 32. inserm-01812710

S. Faraj, M. Bahri, S. Fougeray, A. El Roz, J. Fleurence, J. Véziers, M. D. Leclair, E. Thebaud, F. París, Stéphane Birklé. Neuroblastoma chemotherapy can be augmented by immunotargeting O-acetyl-GD2 tumor-associated ganglioside. OncoImmunology. (2018) e1373232. inserm-01596068

Meriem Bahri, Julien Fleurence, Sébastien Faraj, Mohamed Ben Mostefa Daho, Sophie Fougeray, Stéphane Birklé. Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation. Journal of visualized experiments : JoVE. (2018) epub ahead of print. inserm-01958827

Loig Vaugier, Clément Palpacuer, Emmanuel Rio, Aurore Goineau, David Pasquier, Xavier Buthaud, Guy De Laroche, Véronique Beckendorf, Paul Sargos, Gilles Créhange, Pascal Pommier, Geneviève Loos, Ali Hasbini, Igor Latorzeff, Marlon Silva, Fabrice Denis, Jean-Léon Lagrange, Loïc Campion, Stéphane Supiot. Early toxicity of a phase II trial of combined salvage radiotherapy and hormone therapy in oligometastatic pelvic node relapses of prostate cancer (OLIGOPELVIS GETUG P07). International Journal of Radiation Oncology, Biology, Physics. (2018) 1061-1067. inserm-01980788

Stéphane Supiot, Caroline Rousseau, Mélanie Dore, Catherine Cheze-Le-Rest, Christine Kandel-Aznar, Vincent Potiron, Stéphane Guerif, François Paris, Ludovic Ferrer, Loïc Campion, Philippe Meingan, Grégory Delpon, Mathieu Hatt, Dimitris Visvikis. Evaluation of tumor hypoxia prior to radiotherapy in intermediate-risk prostate cancer using [18]F-fluoromisonidazole PET/CT: a pilot study. Oncotarget. (2018) 10005 – 10015. inserm-01823478

EQUIPE 15

Gwennan André-Grégoire, Nicolas Bidère, Julie Gavard. Temozolomide affects Extracellular Vesicles Released by Glioblastoma Cells. Biochimie. (2018) Epub ahead of print. inserm-01715956

Kathryn Jacobs, Julie Gavard. 3D Endothelial Cell Migration. Chap. de l’ouvrage : Cell Migration. Methods in Molecular Biology. (2018). inserm-01737122

Elizabeth Harford-Wright, Julie Gavard. Apelin, the Devil Inside Brain Tumors. Journal of experimental neuroscience. (2018) eCollection 2018. inserm-01810684

An Thys, Tiphaine Douanne, Nicolas Bidère. Post-translational Modifications of the CARMA1-BCL10-MALT1 Complex in Lymphocytes and Activated B-cell Like Subtype of Diffuse Large B-cell Lymphoma. Frontiers in Oncology. (2018) Epub ahead of print. inserm-01908802

Quentin Roux, Julie Gavard. Endothelial Cell-Cell Junctions in Tumor Angiogenesis. Chap. de l’ouvrage : Tumor Angiogenesis. (2018) 01-29. inserm-01982198

EQUIPE 16

Mark Catherwood, Amy Graham, Robert Cuthbert, Céline Garrec, Betty Gardie, François Girodon, Sophie Laird, Nicholas Cross, Mary Frances McMullin. Absence of CALR Mutations in Idiopathic Erythrocytosis Patients with Low Serum Erythropoietin Levels. Acta Haematologica. (2018). hal-01818466

Marion Lenglet, Florence Robriquet, Klaus Schwarz, Carme Camps, Anne Couturier, David Hoogewijs, Alexandre Buffet, Samantha Jl Knight, Sophie Gad, Sophie Couvé, Franck Chesnel, Mathilde Pacault, Pierre Lindenbaum, Sylvie Job, Solenne Dumont, Thomas Besnard, Marine Cornec, Helene Dreau, Melissa Pentony, Erika Kvikstad, Sophie Deveaux, Nelly Burnichon, Sophie Ferlicot, Mathias Vilaine, Jean-Michaël Mazzella, Fabrice Airaud, Céline Garrec, Laurence Heidet, Sabine Irtan, Elpis Mantadakis, Karim Bouchireb, Klaus-Michael Debatin, Richard Redon, Stéphane Bezieau, Brigitte Bressac-De Paillerets, Bin Tean Teh, François Girodon, Maria-Luigia Randi, Maria Caterina Putti, Vincent Bours, Richard van Wijk, Joachim R. Göthert, Antonis Kattamis, Nicolas Janin, Celeste Bento, Jenny C. Taylor, Yannick Arlot-Bonnemains, Stéphane Richard, Anne-Paule Gimenez-Roqueplo, Holger Cario, Betty Gardie. Identification of a new VHL exon and complex splicing alterations in familial erythrocytosis or von Hippel-Lindau disease. Blood. (2018) hal-01833917

Rini Roy, Evelyn Ang, Emy Komatsu, Ronald Domalaon, Adrien Bosseboeuf, Jean Harb, Sylvie Hermouet, Oleg Krokhin, Frank Schweizer, Hélène Perreault. Absolute Quantitation of Glycoforms of Two Human IgG Subclasses Using Synthetic Fc Peptides and Glycopeptides. Journal of The American Society for Mass Spectrometry. (2018) Journal of The American Society for Mass Spectrometry. inserm-01806658

Jean-Sébastien Souweine, Alice Corbel, Claire Rigothier, Charlotte Dumas de La Roque, Samy Hadjadj, Jean-Paul Cristol, Christian Combe, Edith Bigot-Corbel, Marie-Christine Beauvieux. Interest of albuminuria in nephrology, diabetology and as a marker of cardiovascular risk. Annales de Biologie Clinique. (2018)  hal-02051864

Julia Asp, Vibe Skov, Beatriz Bellosillo, Thomas Kristensen, Eric Lippert, Frank Dicker, Jiri Schwarz, Marzena Wojtaszewska, Lars Palmqvist, Susanna Akiki, Anni Aggerholm, Morten Tolstrup Andersen, François Girodon, Lasse Kjær, Elisabeth Oppliger Leibundgut, Alessandro Pancrazzi, Marta Vorland, Hajnalka Andrikovics, Robert Kralovics, Bruno Cassinat, Margarida Coucelo, Aleksandar Eftimov, Karl Haslam, Rajko Kusec, Dorota Link-Lenczowska, Laurence Lode, Karolina Matiakowska, Dina Naguib, Filippo Navaglia, Guy Novotny, Melanie Percy, Andrey Sudarikov, Sylvie Hermouet, Niels Pallisgaard. International external quality assurance of JAK2 V617F quantification. Annals of Hematology. (2018). inserm-01968802

EQUIPE 17

Swann Gay, Brice Calvignac, Landry Ouanssi Kamtcheu, Thomas Beuvier, Elodie Boller, Martial Sauceau, Sylvie Del Confetto, Franck Boury, Alain Gibaud. Synchrotron X-ray In Situ Tomography of Thermally Induced Phase Separation of Polylactic Acid in 1,4-Dioxane Solution. Crystal Growth and Design. (2018) p.7496-7503. hal-01936837

Franck Bielle, Anna-Luisa Di Stefano, David Meyronnet, Alberto Picca, Chiara Villa, Michèle Bernier, Yohann Schmitt, Marine Giry, Audrey Rousseau, Dominique Figarella-Branger, Claude-Alain Maurage, Emmanuelle Uro-Coste, Anna Lasorella, Antonio Iavarone, Marc Sanson, Karima Mokhtari. Diffuse gliomas with FGFR3-TACC3 fusion have characteristic histopathological and molecular features. Brain Pathology. (2018). hal-01676427

Shubaash Anthiya, Audrey Griveau, Claire Loussouarn, Patrick Baril, Martin Garnett, Jean-Paul Issartel, Emmanuel Garcion. MicroRNA-based Drugs for Brain Tumours. Trends in Cancer. (2018) 222-238. inserm-01691531

Laurence Hoareau, Florian Fouchet, Cynthia Planesse, Sophie Mirbeau, Laurence Sindji, Emmanuel Delay, Régis Roche, Claudia Montero‐Menei, Franck Festy. Combined therapy for critical limb ischaemia: Biomimetic PLGA microcarriers potentiates the pro-angiogenic effect of adipose tissue stromal vascular fraction cells. Journal of Tissue Engineering and Regenerative Medicine. (2018) Epub ahead of print. inserm-01811928

Jean-Michel Lemée, Anne Clavreul, Marc Aubry, Emmanuelle Com, Marie De Tayrac, Jean Mosser, Philippe Menei. Integration of transcriptome and proteome profiles in glioblastoma looking for the missing link. BMC Molecular Biology. (2018) 13. hal-01940252

Florian Bernard, Jean-Michel Lemée, Aram Ter Minassian, Philippe Menei. Right Hemisphere Cognitive Functions: From Clinical and Anatomic Bases to Brain Mapping During Awake Craniotomy Part I: Clinical and Functional Anatomy. World Neurosurgery. (2018) Epub ahead of print. inserm-01823751

Pierre-Jean Mention, Franck Lacoeuille, Georges Leftheriotis, Ludovic Martin, Loukman Omarjee. 18F-Flurodeoxyglucose and 18F-Sodium Fluoride Positron Emission Tomography/Computed Tomography Imaging of Arterial and Cutaneous Alterations in Pseudoxanthoma Elasticum. Circulation: Cardiovascular Imaging. (2018) e007060. hal-01696957

Anne Clavreul, Emilie Roger, Milad Pourbaghi-Masouleh, Laurent Lemaire, Clément Tétaud, Philippe Menei. Development and characterization of sorafenib-loaded lipid nanocapsules for the treatment of glioblastoma. Drug Delivery. (2018) 1756 – 1765. inserm-01908758

E André, N. Daviaud, Laurence Sindji, J. Cayon, R. Perrot, Claudia Montero-Menei. A novel ex vivo Huntington’s disease model for studying GABAergic neurons and cell grafts by laser microdissection. PLoS ONE. (2018) e0193409. inserm-01812641

Muhammad Mansor, Mathie Najberg, Aurélien Contini, Carmen Alvarez-Lorenzo, Emmanuel Garcion, Christine Jerôme, Frank Boury. Development of a non-toxic and non-denaturing formulation process for encapsulation of SDF-1α into PLGA/PEG-PLGA nanoparticles to achieve sustained release. European Journal of Pharmaceutics and Biopharmaceutics. (2018) Epub ahead of print. inserm-01691907

Hélène Lajous, Raphaël Riva, Bénédicte Lelièvre, Clément Tétaud, Sylvie Avril, François Hindré, Frank Boury, Christine Jérôme, Philippe Lecomte, Emmanuel Garcion. Hybrid Gd 3+ /cisplatin cross-linked polymer nanoparticles enhance platinum accumulation and formation of DNA adducts in glioblastoma cell lines. Biomaterials Science. (2018) 2386-2409. inserm-01959991

Matthieu Dreyfus, Michèle El-Atifi, Magali Court, Marie Bidart, Charles Coutton, Céline Leclech, Bruno Ballester, Emmanuel Garcion, Ali Bouamrani, François Berger, Didier Wion. Reprogramming glioma cell cultures with retinoic acid: Additional arguments for reappraising the potential of retinoic acid in the context of personalized glioma therapy. Glioma. (2018) 66-78. inserm-01959941

Blandine Boisselier, Frédéric Dugay, Marc-Antoine Belaud-Rotureau, Anne Coutolleau, Emmanuel Garcion, Philippe Menei, Philippe Guardiola, Audrey Rousseau. Whole genome duplication is an early event leading to aneuploidy in IDH-wild type glioblastoma. Oncotarget. (2018) 36017-36028. inserm-01960034