Publications 2017

EQUIPE 1

Stéphanie Dirou, Arnaud Chambellan, Patrice Chevallier, Patrick Germaud, Guillaume Lamirault, Pierre-Antoine Gourraud, Bastien Perrot, Béatrice Delasalle, Bastien Forestier, Thierry Guillaume, Pierre Peterlin, Alice Garnier, Antoine Magnan, François-Xavier Blanc, Patricia Lemarchand. Deconditioning, fatigue and impaired quality of life in long-term survivors after allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplantation. (2017) Epub ahead of print. inserm-01684314

Sébastien Küry, Geeske van Woerden, Thomas Besnard, Martina Onori, Xénia Latypova, Meghan Towne, Megan Cho, Trine Prescott, Melissa Ploeg, Stephan Sanders, Holly Stessman, Aurora Pujol, Ben Distel, Laurie Robak, Jonathan Bernstein, Anne-Sophie Denommé-Pichon, Gaëtan Lesca, Elizabeth Sellars, Jonathan Berg, Wilfrid Carré, Øyvind Busk, Bregje Van Bon, Jeff Waugh, Matthew Deardorff, George Hoganson, Katherine Bosanko, Diana Johnson, Tabib Dabir, Øystein Lunde Holla, Ajoy Sarkar, Kristian Tveten, Julitta De Bellescize, Geir Braathen, Paulien Terhal, Dorothy Grange, Arie Van Haeringen, Christina Lam, Ghayda Mirzaa, Jennifer Burton, Elizabeth Bhoj, Jessica Douglas, Avni Santani, Addie Nesbitt, Katherine Helbig, Marisa Andrews, Amber Begtrup, Sha Tang, Koen L.I. van Gassen, Jane Juusola, Kimberly Foss, Gregory Enns, Ute Moog, Katrin Hinderhofer, Nagarajan Paramasivam, Sharyn Lincoln, Brandon Kusako, Pierre Lindenbaum, Eric Charpentier, Catherine Nowak, Elouan Cherot, Thomas Simonet, Claudia A.L. Ruivenkamp, Sihoun Hahn, Catherine Brownstein, Fan Xia, Sébastien Schmitt, Wallid Deb, Dominique Bonneau, Mathilde Nizon, Delphine Quinquis, Jamel Chelly, Gabrielle Rudolf, Damien Sanlaville, Philippe Parent, Brigitte Gilbert-Dussardier, Annick Toutain, Vernon Sutton, Jenny Thies, Lisenka E.L.M. Peart-Vissers, Pierre Boisseau, Marie Vincent, Andreas Grabrucker, Christèle Dubourg, Undiagnosed Diseases Network, Wen-Hann Tan, Nienke Verbeek, Martin Granzow, Gijs W.E. Santen, Jay Shendure, Bertrand Isidor, Laurent Pasquier, Richard Redon, Yaping Yang, Matthew State, Tjitske Kleefstra, Benjamin Cogné, GEM HUGO, Deciphering Study, Slavé Petrovski, Kyle Retterer, Evan Eichler, Jill Rosenfeld, Pankaj Agrawal, Stéphane Bézieau, Sylvie Odent, Ype Elgersma, Sandra Mercier. De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability. American Journal of Human Genetics. (2017) 768 – 788. inserm-01813739

Raphaëlle Riou, Céline Bressollette-Bodin, David Boutoille, Katia Gagne, Audrey Rodallec, Maeva Lefebvre, François Raffi, David Senitzer, Berthe-Marie Imbert-Marcille, Christelle Retière. Severe Symptomatic Primary Human Cytomegalovirus Infection despite Effective Innate and Adaptive Immune Responses. Journal of Virology. (2017) e02245-16. inserm-01805573

Raphael Carapito, Martina Konantz, Catherine Paillard, Zhichao Miao, Angélique Pichot, Magalie Leduc, Yaping Yang, Katie Bergstrom, Donald Mahoney, Deborah Shardy, Ghada Alsaleh, Lydie Naegely, Aline Kolmer, Nicodème Paul, Antoine Hanauer, Véronique Rolli, Joëlle Müller, Elisa Alghisi, Loïc Sauteur, Cécile Macquin, Aurore Morlon, Consuelo Sebastia Sancho, Patrizia Amati-Bonneau, Vincent Procaccio, Anne-Laure Mosca-Boidron, Nathalie Marle, Nael Osmani, Olivier Lefebvre, Jacky Goetz, Sule Unal, Nurten Akarsu, Mirjana Radosavljevic, Marie-Pierre Chenard, Fanny Rialland, Audrey Grain, Marie-Christine Béné, Marion Eveillard, Vincent Vincent, Julien Guy, Laurence Faivre, Christel Thauvin-Robinet, Julien Thevenon, Kasiani Myers, Mark Fleming, Akiko Shimamura, Elodie Bottollier-Lemallaz, Eric Westhof, Claudia Lengerke, Bertrand Isidor, Seiamak Bahram. Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond–like features. Journal of Clinical Investigation. (2017) 4090-4103. hal-02171273

Pierre Boisseau, Camille Debord, Marion Eveillard, Agnès Quéméner, Marianne Sigaud, Mathilde Giraud, Patricia Talarmain, C. Thomas, G. Landeau, Stéphane Bezieau, Brigitte Pan-Petesch, Marie-Christine Béné, Marc Fouassier. Two novel variants of uncertain significance in GP9 associated with Bernard–Soulier syndrome: Are they true mutations? Platelets. (2017) 316 – 318. inserm-01807674

Mickael Vourc’h, Antoine Roquilly, Alexis Broquet, Gaëlle David, Philippe Hulin, Cédric Jacqueline, Jocelyne Caillon, Christelle Retière, Karim Asehnoune. Exoenzyme T Plays a Pivotal Role in the IFN-γ Production after Pseudomonas Challenge in IL-12 Primed Natural Killer Cells. Frontiers in Immunology. (2017) 1283 – 1283. inserm-01813287

Jocelyn Ollier, Régine Vivien, Henri Vié, Béatrice Clémenceau. Transfection of FcγRIIIa (CD16) Alone Can Be Sufficient To Enable Human αβTCR T Lymphocytes To Mediate Antibody-Dependent Cellular Cytotoxicity. ImmunoHorizons. (2017) 63 – 70. inserm-01563703

Henri Vié, Béatrice Clémenceau. Transfert adoptif de lymphocytes T : Adoptive transfer of T lymphocytes. Transfusion Clinique et Biologique. (2017) 256 – 262. inserm-01806932

E. Rederstorff, Gildas Réthoré, Pierre Weiss, Sophie Sourice, Sarah Beck-Cormier, E. Mathieu, Mike Maillasson, Yannick Jacques, S. Colliec-Jouault, B. Fellah, Jérome Guicheux, Claire Vinatier. Enriching a cellulose hydrogel with a biologically active marine exopolysaccharide for cell-based cartilage engineering. Journal of Tissue Engineering and Regenerative Medicine. (2017) 1152 – 1164. inserm-01818096

Dihia Meghnem, Sébastien Morisseau, Marie Frutoso, Kilian Trillet, Mike Maillasson, Isabelle Barbieux, Sarah Khaddage, Isabelle Leray, Markus Hildinger, Agnès Quéméner, Yannick Jacques, Erwan Mortier. Cutting Edge: Differential Fine-Tuning of IL-2- and IL-15- Dependent Functions by targeting their Common IL-2/15Rβ/γc Receptor. Journal of Immunology. (2017) 4563-4568. inserm-01524397

Bercelin Maniangou, Nolwenn Legrand, Mehdi Alizadeh, Ulysse Guyet, Catherine Willem, Gaëlle David, Eric Charpentier, Alexandre Walencik, Christelle Retière, Katia Gagne. Killer Immunoglobulin-Like Receptor Allele Determination Using Next-Generation Sequencing Technology. Frontiers in Immunology. (2017) 547. inserm-01807094

Alexis Rossignol, Véronique Bonnaudet, Béatrice Clémenceau, Henri Vié, Laurent Bretaudeau. A high-performance, non-radioactive potency assay for measuring cytotoxicity: A full substitute of the chromium-release assay targeting the regulatory-compliance objective. mAbs. (2017) 521 – 535. inserm-01806965

Agnès Quéméner, Mike Maillasson, Laurence Arzel, Benoit Sicard, Romy Vomiandry, Erwan Mortier, Didier Dubreuil, Yannick Jacques, Jacques Lebreton, Monique Mathé-Allainmat. Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization. Journal of Medicinal Chemistry. (2017) 6249-6272. inserm-01550121

Emilie Dugast, Gaëlle David, Romain Oger, Richard Danger, Jean-Paul Judor, Katia Gagne, Mélanie Chesneau, Nicolas Degauque, Pascale Paul, Christophe Picard, Pierrick Guerif, Sophie Conchon, Magali Giral, Nadine Gervois, Christelle Retière, Sophie Brouard. Broad Impairment of Natural Killer Cells from Operationally Tolerant Kidney Transplanted Patients. Frontiers in Immunology. (2017) 1721. hal-01712225

Julien Fleurence, Sophie Fougeray, Meriem Bahri, Denis Cochonneau, Béatrice Clémenceau, François Paris, Andras Heczey, Stéphane Birklé. Targeting-Acetyl-GD2 Ganglioside for Cancer Immunotherapy. Journal of Immunology Research. (2017) [Epub ahead of print]. inserm-01474322

EQUIPE 2

Tiphaine Delaunay, Mathilde Violland, Nicolas Boisgerault, Soizic Dutoit, Virginie Vignard, Christian Münz, Monique Gannagé, Brigitte Dréno, Kristine Vaivode, Dace Pjanova, Nathalie Labarrière, Yaohe Wang, E Chiocca, Fabrice Le Boeuf, John Bell, Philippe Erbs, Frédéric Tangy, Marc Grégoire, Jean-François Fonteneau. Oncolytic viruses sensitize human tumor cells for NY-ESO-1 tumor antigen recognition by CD4+ effector T cells. OncoImmunology. (2017) inserm-01644345

Sylvain Simon, Virginie Vignard, Emilie Varey, Tiphaine Parrot, Anne-Chantal Knol, Amir Khammari, Nadine Gervois, François Lang, Brigitte Dréno, Nathalie Labarrière. Emergence of High-Avidity Melan-A–Specific Q2 Clonotypes as a Reflection of Anti–PD-1 Q3 Clinical Efficacy. Cancer Research. (2017) 7083 – 7093. inserm-01636933

Stéphane Corvec, Sarah Dellière, Aurélie Guillouzouic, Guillaume Aubin. Can 16S rRNA PCR be the solution for a rapid detection of Propionibacterium acnes in surgical shoulder or spine samples? Comments on » A rapid method for detecting Propionibacterium acnes in surgical biopsy specimens from the shoulder « .Journal of Shoulder and Elbow Surgery. (2017) e203-e204. inserm-01525858

Stanimir Kambarev, Stéphane Corvec, Annick Chauty, Estelle Marion, Laurent Marsollier, Frédéric Pecorari. Draft Genome Sequence of Mycobacterium ulcerans S4018 Isolated from a Patient with an Active Buruli Ulcer in Benin, Africa. Genome Announcements. (2017) inserm-01550042

Stanimir Kambarev, Frédéric Pecorari, Stéphane Corvec. Draft Genome Sequences of Two Highly Erythromycin-Resistant Streptococcus gallolyticus subsp. gallolyticus Isolates Containing a Novel Tn916-Like Element, Tn6331. Genome Announcements. (2017) Epub ahead of print. inserm-01550034

Sophie Wylomanski, Marc Denis, Sandrine Théoleyre, Réjane Bouquin, Audrey Vallée, Anne-Chantal Knol, Mélanie Saint-Jean, Lucie Peuvrel, Brigitte Dréno, Gaëlle Quéreux. BRAF mutations might be more common than supposed in vulvar melanomas. Experimental Dermatology. (2017) 210 – 213. inserm-01808469

Sarah Le Naour, Lucie Peuvrel, Mélanie Saint-Jean, Brigitte Dréno, Gaëlle Quereux. Three new cases of bullous pemphigoid during anti-PD-1 antibody therapy. Journal of the European Academy of Dermatology and Venereology. (2017) e104-e106. inserm-01807978

S Vildy, Jean Michel Nguyen, A Gaultier, Anne-Chantal Knol, Amir Khammari, Brigitte Dréno. Impact of the time interval between lymph node recurrence and lymphadenectomy on melanoma patient survival. European Journal of Dermatology. (2017) inserm-01819482

Raul Perret, Nicolas Josselin, Anne-Chantal Knol, Amir Khammari, Julie Cassecuel, Lucie Peuvrel, Brigitte Dréno. Histopathological aspects of cutaneous erythematous-papular eruptions induced by immune checkpoint inhibitors for the treatment of metastatic melanoma. International Journal of Dermatology. (2017) 527-533. inserm-01808063

N. Jacquelot, M.P. Roberti, D.P. Enot, S. Rusakiewicz, N. Ternès, S. JEGOU, D.M. Woods, A.L. Sodré, M. Hansen, Y. Meirow, M. Sade-Feldman, A. Burra, S.S. Kwek, C. Flament, M. Messaoudene, C.P.M. Duong, L. Chen, B.S. Kwon, A.C. Anderson, V.K. Kuchroo, B. Weide, F. Aubin, C. Borg, S. Dalle, O. Beatrix, M. Ayyoub, B. Balme, G. Tomasic, A.M. Di Giacomo, M. Maio, D. Schadendorf, I. Melero, Brigitte Dréno, Amir Khammari, R. Dummer, M. Levesque, Y. Koguchi, L. Fong, M. Lotem, M. Baniyash, H. Schmidt, I.M. Svane, G. Kroemer, A. Marabelle, S. Michiels, A. Cavalcanti, M.J. Smyth, J.S. Weber, A.M. Eggermont, Laurence Zitvogel. Predictors of responses to immune checkpoint blockade in advanced melanoma. Nature Communications. (2017) 592. inserm-01824289

Laurence Zitvogel, Eric Vivier, Frederic Vely, Florence Faure, Brigitte Dréno, Houssem Benlalam, Fanny Bouquet, Ariel Savina, Eric Pasmant, Antoine Toubert, Marie-Francoise Avril, Anne Caignard, Alexandra Frazao, Marina Colombo, Emmanuelle Fourmentraux-Neves, Meriem Messaoudene, Sylvie Rusakiewicz. Shifting the Balance of Activating and Inhibitory Natural Killer Receptor Ligands on BRAF(V600E) Melanoma Lines with Vemurafenib. Cancer Immunology Research. (2017) 582-593. hal-01996164

Guillaume Herbreteau, Audrey Vallée, Anne-Chantal Knol, Sandrine Théoleyre, Gaëlle Quéreux, Amir Khammari, Brigitte Dréno, Marc Denis. ADN tumoral circulant : aspects analytiques et intérêt dans la prise en charge des patients ayant un mélanome métastatique : Circulating tumour DNA: analytical aspects and clinical applications for metastatic melanoma patients. Annales de Biologie Clinique. (2017) 619-630. inserm-01808416

Guillaume Aubin, Marc Baud’Huin, Jean-Philippe Lavigne, Régis Brion, François Gouin, Didier Lepelletier, Cédric Jacqueline, Dominique Heymann, Karim Asehnoune, Stéphane Corvec. Interaction of Cutibacterium (formerly Propionibacterium) acnes with bone cells: a step toward understanding bone and joint infection development. Scientific Reports. (2017) 42918. inserm-01671739

Guillaume Aubin, Jean-Philippe Lavigne, Yohan Foucher, Sarah Dellière, Didier Lepelletier, François Gouin, Stéphane Corvec. Tropism and virulence of Cutibacterium (formerly Propionibacterium) acnes involved in implant-associated infection. Anaerobe. (2017) 73 – 78. inserm-01814725

Guillaume Aubin, Grâce Ada Da Silva, Yoshinobu Eishi, Cédric Jacqueline, Frédéric Altare, Stéphane Corvec, Karim Asehnoune. Immune discrepancies during in vitro granuloma formation in response to Cutibacterium (formerly Propionibacterium ) acnes infection. Anaerobe. (2017) 172 – 176. inserm-01667138

Gaëlle Quéreux, Sophie Wylomanski, Rejane Bouquin, Mélanie Saint-Jean, Lucie Peuvrel, Anne-Chantal Knol, Matthieu Hanf, Brigitte Dréno. Are checkpoint inhibitors a valuable option for metastatic or unresectable vulvar and vaginal melanomas?. Journal of the European Academy of Dermatology and Venereology. (2017) e39 – e40. inserm-01808303

Gaëlle Quéreux, Guillaume Herbreteau, Anne-Chantal Knol, Audrey Vallée, Amir Khammari, Sandrine Théoleyre, Mélanie Saint-Jean, Brigitte Dréno, Marc Denis. Efficient treatment of a metastatic melanoma patient with a combination of BRAF and MEK inhibitors based on circulating tumor DNA analysis: a case report. BMC Biochemistry. (2017) 320. inserm-01807889

Eve-Marie Takoudju, Aurélie Guillouzouic, Stanimir Kambarev, Frédéric Pécorari, Stéphane Corvec. In vitro emergence of fluoroquinolone resistance in Cutibacterium (formerly Propionibacterium ) acnes and molecular characterization of mutations in the gyrA gene. Anaerobe. (2017) 194 – 200. inserm-01636129

Cédric Rat, Sarah Houd, Aurélie Gaultier, Charlotte Grimault, Gaëlle Quereux, Alain Mercier, Laurent Letrilliart, Brigitte Dréno, Jean Michel Nguyen. General practitioner management related to skin cancer prevention and screening during standard medical encounters: a French cross-sectional study based on the International Classification of Primary Care. BMJ Open. (2017) e013033. inserm-01808743

Cédric Rat, Sandrine Hild, Aurelie Gaultier, Amir Khammari, Angelique Bonnaud-Antignac, Gaëlle Quereux, Brigitte Dréno, Jean Michel Nguyen. Anxiety, locus of control and sociodemographic factors associated with adherence to an annual clinical skin monitoring: a cross-sectional survey among 1000 high-risk French patients involved in a pilot-targeted screening programme for melanoma. BMJ Open. (2017) e016071. inserm-01808160

Cédric Rat, Brigitte Dréno, Jean-Michel Nguyen. Why We Should Focus on Melanoma-Targeted Screening Strategies. Dermatology. (2017) 480-481. inserm-01813132

Brigitte Dréno, Richard Martin, Dominique Moyal, Jessica Henley, Amir Khammari, Sophie Seité. Skin microbiome and acne vulgaris : Staphylococcus , a new actor in acne. Experimental Dermatology. (2017) 798 – 803. inserm-01807656

Anne Cowppli-Bony, Aurélie Gaultier, Jean-Michel Nguyen, Cédric Rat, Pogu C, D. Le Donné, C. Latour, G. Bianco, F. Nanin. Effect of Physician Notification Regarding Nonadherence to Colorectal Cancer Screening on Patient Participation in Fecal Immunochemical Test Cancer Screening: A Randomized Clinical Trial.. JAMA Ophthalmology. (2017). inserm-01628347

EQUIPE 3

Sylvain Simon, Virginie Vignard, Emilie Varey, Tiphaine Parrot, Anne-Chantal Knol, Amir Khammari, Nadine Gervois, François Lang, Brigitte Dréno, Nathalie Labarrière. Emergence of High-Avidity Melan-A–Specific Q2 Clonotypes as a Reflection of Anti–PD-1 Q3 Clinical Efficacy. Cancer Research. (2017) 7083 – 7093. inserm-01636933

Sylvain Simon, Nathalie Labarrière. PD-1 expression on tumor-specific T cells: Friend or foe for immunotherapy?. OncoImmunology. (2017). inserm-01592666

Sylvain Simon, Maud Charpentier, Ignacio Anegon, Nathalie Labarrière. Conference Scenes: Immunotherapies in transplantation and cancer. Immunotherapy. (2017) Epub ahead of print. inserm-01639012

Sylvain Simon, Maud Charpentier, Ignacio Anegon, Nathalie Labarrière. Immunotherapies in transplantation and cancer: 22nd NAT meeting/2nd NAT LabEx IGO joint meeting; 1–2 June 2017, Nantes, France. Cancer Immunology, Immunotherapy. (2017) 867-870. inserm-02153746

Sébastien Küry, Thomas Besnard, Frédéric Ebstein, Tahir N. Khan, Tomasz Gambin, Jessica Douglas, Carlos A. Bacino, Stephan J. Sanders, Andrea Lehmann, Xenia Latypova, Kamal Khan, Mathilde Pacault, Stephanie Sacharow, Kimberly Glaser, Eric Bieth, Laurence Perrin-Sabourin, Marie-Line Jacquemont, Megan T. Cho, Elizabeth Roeder, Anne-Sophie Denommé-Pichon, Kristin G. Monaghan, Bo Yuan, Fan Xia, Sylvain Simon, Dominique Bonneau, Philippe Parent, Brigitte Gilbert-Dussardier, Sylvie Odent, Annick Toutain, Laurent Pasquier, Deborah Barbouth, Chad A. Shaw, Ankita Patel, Janice L. Smith, Weimin Bi, Sébastien Schmitt, Wallid Deb, Mathilde Nizon, Sandra Mercier, Marie Vincent, Caroline Rooryck, Valérie MALAN, Ignacio Briceno, Alberto Gómez, Kimberly M. Nugent, James B. Gibson, Benjamin Cogné, James R. Lupski, Holly A. F. Stessman, Evan E. Eichler, Kyle Retterer, Yaping Yang, Richard Redon, Nicholas Katsanis, Jill A. Rosenfeld, Peter-Michael Kloetzel, Christelle Golzio, Stéphane Bézieau, Paweł Stankiewicz, Bertrand Isidor. De Novo Disruption of the Proteasome Regulatory Subunit PSMD12 Causes a Syndromic Neurodevelopmental Disorder. American Journal of Human Genetics. (2017) 352-363. hal-01478814

EQUIPE 4

Nicolas Boisgerault, Marc Gregoire, Jean-François Fonteneau. Viral cancer therapies : are they ready for combination with other immunotherapies ?. Future Oncology. (2017) 1569-1571. inserm-01582475

Daniel Pouliquen, Béatrice Nawrocki-Raby, Joëlle Nader, Stéphanie Blandin, Myriam Robard, Philippe Birembaut, Marc Grégoire. Evaluation of intracavitary administration of curcumin for the treatment of sarcomatoid mesothelioma. Oncotarget. (2017) [Epub ahead of print]. inserm-01480303

Camille Linot, Julien Poly, Joanna Boucard, Daniel Pouliquen, Steven Nedellec, Philippe Hulin, Nadège Marec, Paolo Arosio, Alessandro Lascialfari, Andrea Guerrini, Claudio Sangregorio, Marc Lecouvey, Lenaic Lartigue, Christophe Blanquart, Eléna Ishow. PEGylated Anionic Magneto-Fluorescent Nanoassemblies: Impact of their Interface Structure on MRI Contrast and Cellular Uptake. ACS Applied Materials & Interfaces. (2017) 14242-14257. inserm-01522631

EQUIPE 5

Thibault Colombani, Pauline Peuziat, Laurence Dallet, Thomas Haudebourg, Mathieu Mével, Mathieu Berchel, Olivier Lambert, Damien Habrant, Bruno Pitard. Self-assembling complexes between binary mixtures of lipids with different linkers and nucleic acids promote universal mRNA, DNA and siRNA delivery. Journal of Controlled Release. (2017) 131 – 142. inserm-01473687
Jacques Le Pendu, Joana Abrantes, Stéphane Bertagnoli, Jean-Sébastien Guitton, Ghislaine Le Gall-Reculé, Ana Margarida Lopes, Stéphane Marchandeau, Fernando Alda, Tereza Almeida, Paulo Celio Alves, Juan Barcena, Galina Burmakina, Esther Blanco, Carlos Calvete, Patrizia Cavadini, Brian Cooke, Kevin Dalton, Miguel Delibes Mateos, Wieslaw Deptula, John Sebastian Eden, Fang Wang, Catarina Ferreira, Paula Ferreira, Pilar Foronda, David Gonçalves, Dolores Gavier-WidEN, Robin Hall, Beata Hukowska-Szematowicz, Peter Kerr, John Kovaliski, Antonio Lavazza, Jackie Mahar, Alexander Malogolovkin, Raquel Marques, Sara Marques, Aaron Martin-Alonso, Pedro Monterroso, Sacramento Moreno, Greg Mutze, Aleksija Neimanis, Paulina Niedzwiedzka-Rystwej, David Peacock, Francisco Parra, Mara Rocchi, Carlos Rouco, Nathalie Ruvoen-Clouet, Eliane Silva, Diogo Silvério, Tanja Strive, Gertrudes Thompson, Beata Tokarz-Deptula, Pedro Esteves. Proposal for a unified classification system and nomenclature of lagoviruses. Journal of General Virology. (2017) Epub ahead of print. inserm-01563782

Guillaume Aubin, Grâce Ada Da Silva, Yoshinobu Eishi, Cédric Jacqueline, Frédéric Altare, Stéphane Corvec, Karim Asehnoune. Immune discrepancies during in vitro granuloma formation in response to Cutibacterium (formerly Propionibacterium) acnes infection. Anaerobe. (2017) 172 – 176. inserm-01667138

Ana Lopes, Adrien Breiman, Mónica Lora, Béatrice Le Moullac-Vaidye, Oxana Galanina, Kristina Nyström, Stéphane Marchandeau, Ghislaine Le Gall-Reculé, Tanja Strive, Aleksija Neimanis, Nicolai Bovin, Nathalie Ruvoën-Clouet, Pedro Esteves, Joana Abrantes, Jacques Le Pendu. Relationships between host-species specificities and glycan specificities of 1 pathogenic and non-pathogenic lagoviruses. Journal of Virology. (2017) Epub ahead of print. inserm-01636824

EQUIPE 6

Rafael Mahieu, Viviane Cassisa, Diane Sanderink, Rachel Chenouard, Hélène Pailhoriès, Marie Kempf, Vincent Dubée, Matthieu Eveillard. Iterative fecal microbiota transplantations for eradicating digestive colonization with carbapenemase-producing Enterobacteriaceae: is it worth it?. Infection Control and Hospital Epidemiology. (2017). inserm-01559275

Rafael Mahieu, Viviane Cassisa, Delphine Hilliquin, Noémie Coron, Hélène Pailhories, Marie Kempf, Marie-Laure Joly-Guillou, Matthieu Eveillard. Impact of faecal microbiota transplantation on mouse digestive colonization with two extensively resistant bacteria. Journal of Infection. (2017) 75-77. inserm-01522741

Ok-Ryul Song, Han-Byul Kim, Samuel Jouny, Isabelle Ricard, Alexandre Vandeputte, Nathalie Deboosere, Estelle Marion, Christophe Queval, Pierre Lesport, Emmanuel Bourinet, Daniel Henrion, Seog Bae Oh, Guillaume Lebon, Guillaume Sandoz, Edouard Yeramian, Laurent Marsollier, Priscille Brodin. A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone. Toxins. (2017) 227. inserm-01582485
Ok-Ryul Song, Christophe Queval, Raffaella Iantomasi, Vincent Delorme, Sabrina Marion, Romain Veyron-Churlet, Elisabeth Werkmeister, Michka Popoff, Isabelle Ricard, Samuel Jouny, Nathalie Deboosere, Frank Lafont, Alain Baulard, Edouard Yeramian, Laurent Marsollier, Eik Hoffmann, Priscille Brodin. ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton. EMBO Reports. (2017) Epub ahead of print. inserm-01636290

Marie Robbe-Saule, Jérémie Babonneau, Odile Sismeiro, Laurent Marsollier, Estelle Marion. An Optimized Method for Extracting Bacterial RNA from Mouse Skin Tissue Colonized by Mycobacterium ulcerans. Frontiers in microbiology. (2017) 512. inserm-01508404

Hélène Pailhories, Linda Hadjadj, Rafael Mahieu, Nicolas Crochette, Jean-Marc Rolain, Marie Kempf. Fortuitous diagnosis of NDM-1producing Acinetobacter pittii carriage in a patient from France with no recent history of travel. Journal of Antimicrobial Chemotherapy. (2017) 942-944. hal-01521227

Anita Umerska, Viviane Cassisa, Guillaume Bastiat, Nada Matougui, Hassan Nehme, Florence Manero, Matthieu Eveillard, Patrick Saulnier. Synergistic interactions between antimicrobial peptides derived from plectasin and lipid nanocapsules containing monolaurin as a cosurfactant against Staphylococcus aureus. International Journal of Nanomedicine. (2017) 5687 – 5699. inserm-01814912

EQUIPE 7

Ombeline Roche, Nathalie Aladjidi, Josué Rakotonjanahary, Guy Leverger, Thierry Leblanc, Caroline Thomas, Marlène Pasquet, Mary-France Courcoux, Sophie Bayart, Marion Gilibert-Yvert, Bénédicte Neven, Pierre Quartier, Isabelle Pellier. Evaluation of the efficiency of hydroxychloroquine in treating children with immune thrombocytopenia (ITP). American Journal of Hematology. (2017) E79 – E81. inserm-01815546

Nina Salabert-Le Guen, Caroline Hemont, Agathe Delbove, Caroline Poli, Cécile Braudeau, Aurelie Fantou, Karine Amouriaux, Gaëlle Bériou, Jerome C Martin, Luc Colas, Vassili Soumelis, Regis Josien. Thymic stromal lymphopoietin does not activate human basophils.. Journal of Allergy and Clinical Immunology. (2017). inserm-01885566

Mathilde Hunault-Berger, N. Maillard, C. Himberlin, C. Recher, Aline Schmidt-Tanguy, B Choufi, C Bonmati, M. Carré, M-A Couturier, E Daguindau, J-P Marolleau, F Orsini-Piocelle, J Delaunay, E Tavernier, S Lissandre, M Ojeda-Uribe, L. Sanhes, L. Sutton, A. Banos, LM Fornecker, M. Bernard, D Bouscary, A. Saad, M Puyade, V Rouillé, I Luquet, MC Béné, Jean-François Hamel, F. Dreyfus, Norbert Ifrah, A Pigneux. Maintenance therapy with alternating azacitidine and lenalidomide in elderly fit patients with poor prognosis acute myeloid leukemia: a phase II multicentre FILO trial. Blood Cancer Journal. (2017) e568. inserm-01814864

L. Boucret, C. Bris, Valérie Seegers, D. Goudenège, V. Desquiret-Dumas, M. Domin-Bernhard, V Ferré-L’hotellier, P. Bouet, P. Descamps, P. Reynier, V. Procaccio, P. May-Panloup. Deep sequencing shows that oocytes are not prone to accumulate mtDNA heteroplasmic mutations during ovarian ageing. Human Reproduction. (2017) 2101 – 2109. inserm-01815346

Jean-François Augusto, Caroline Poli, Céline Beauvillain, Jean-François Subra, Sébastien Jaillon, Gilles Renier, Alain Chevailler, Xavier Puéchal, Yves Delneste, Pascale Jeannin. Anti-pentraxin antibodies in autoimmune systemic diseases: Focus on anti-pentraxin-3 autoantibodies. International Reviews of Immunology. (2017) 145 – 153. inserm-01814831

Helen D. Bailey, Brigitte Lacour, Léa Guerrini-Rousseau, Anne-Isabelle Bertozzi, Pierre Leblond, Cécile Faure-Conter, Isabelle Pellier, Claire Freycon, François Doz, Stéphanie Puget, Stéphane Ducassou, Laurent Orsi, Jacqueline Clavel. Parental smoking, maternal alcohol, coffee and tea consumption and the risk of childhood brain tumours: the ESTELLE and ESCALE studies (SFCE, France). Cancer Causes and Control. (2017) 719-732. inserm-01824356

Helen Bailey, Paula Rios, Brigitte Lacour, Léa Guerrini-Rousseau, Anne-Isabelle Bertozzi, Pierre Leblond, Cécile Faure-Conter, Isabelle Pellier, Claire Freycon, Jean Michon, Stéphanie Puget, Stéphane Ducassou, Laurent Orsi, Jacqueline Clavel. Factors related to pregnancy and birth and the risk of childhood brain tumours: The ESTELLE and ESCALE studies (SFCE, France). International Journal of Cancer. (2017) 1757 – 1769. inserm-01824419

Caroline Poli, Jean-François Augusto, Jonathan Dauvé, Clément Adam, Laurence Preisser, Vincent Larochette, Pascale Pignon, Ariel Savina, Simon Blanchard, Jean-François Subra, Alain Chevailler, Vincent Procaccio, Anne Croué, Christophe Créminon, Alain Morel, Yves Delneste, Helmut Fickenscher, Pascale Jeannin. IL-26 Confers Proinflammatory Properties to Extracellular DNA. Journal of Immunology. (2017) 3650-3661. inserm-01514382

EQUIPE 8

Sophie De Carné Trécesson, Frédérique Souazé, Agnes Basseville, Anne-Charlotte Bernard, Jessie Pécot, Jonathan Lopez, Margaux Bessou, Kristopher Sarosiek, Anthony Letaï, Sophie Barillé-Nion, Isabelle Valo, Olivier Coqueret, Catherine Guette, Mario Campone, Fabien Gautier, Philippe Juin. BCL-XL directly modulates RAS signalling to favour cancer cell stemnes.. Nature Communications. (2017) 1123. inserm-01628330

Pierre-Samuel Gillardin, Géraldine Descamps, Sophie Maiga, Benoit Tessoulin, Hanane Djamai, Benedetta Lucani, David Chiron, Philippe Moreau, Steven Le Gouill, Martine Amiot, Catherine Pellat-Deceunynck, Agnès Moreau-Aubry. Decitabine and Melphalan Fail to Reactivate p73 in p53 Deficient Myeloma Cells. International Journal of Molecular Sciences. (2017) inserm-01691503

P Mathot, M Grandin, G Devailly, Frédérique Souazé, V. Cahais, S. Moran, Mario Campone, Z Herceg, M Esteller, Philippe Juin, P. Mehlen, R Dante. DNA methylation signal has a major role in the response of human breast cancer cells to the microenvironment. Oncogenesis. (2017) e390. inserm-01668763

Kristell Oizel, Cynthia Chauvin, Lisa Oliver, Catherine Gratas, Fanny Geraldo, Ulrich Jarry, Emmanuel Scotet, Marion Rabe, Marie-Clotilde Alves-Guerra, Raluca Teusan, Fabien Gautier, Delphine Loussouarn, Vincent Compan, Jean-Claude Martinou, François Vallette, Claire Pecqueur. Efficient Mitochondrial Glutamine Targeting Prevails Over Glioblastoma Metabolic Plasticity. Clinical Cancer Research. (2017) Epub ahead of print. inserm-01595798
Jérôme Abadie, Frédérique Nguyen, Delphine Loussouarn, Laura Pena, Adelina Gama, Natascha Rieder, Anton Belousov, Ingrid Bemelmans, Laëtitia Jaillardon, Catherine Ibisch, Mario Campone. Canine invasive mammary carcinomas as models of human breast cancer. Part 2: immunophenotypes and prognostic significance. Breast Cancer Research and Treatment. (2017) Epub ahead of print. inserm-01629625

Frédérique Nguyen, Laura Pena, Catherine Ibisch, Delphine Loussouarn, Adelina Gama, Natascha Rieder, Anton Belousov, Mario Campone, Jérôme Abadie. Canine invasive mammary carcinomas as models of human breast cancer. Part 1: natural history and prognostic factors. Breast Cancer Research and Treatment. (2017) Epub ahead of print. inserm-01629480

Caroline Corbel, Sara Sartini, Elisabetta Levati, Pierre Colas, Laurent Maillet, Cyril Couturier, Barbara Montanini, Stéphane Bach. Screening for Protein-Protein Interaction Inhibitors Using a Bioluminescence Resonance Energy Transfer (BRET)-Based Assay in Yeast. Slas Discovery. (2017) 751-759. hal-01697260

EQUIPE 9

Quentin Séry, Marion Rabé, Lisa Oliver, François Vallette, Catherine Gratas. HB-EGF is associated with DNA damage and Mcl-1 turnover in human glioma cell lines treated by Temozolomide. Biochemical and Biophysical Research Communications. (2017) 1377 – 1383. inserm-01813093

Peter Ratcliffe, Peppi Koivunen, Johanna Myllyharju, Jiannis Ragoussis, Judith Bovée, Ines Batinic-Haberle, Claire Vinatier, Valérie Trichet, Florence Robriquet, Lisa Oliver, Betty Gardie. Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways: from physiology to therapeutics. Hypoxia. (2017) inserm-01845039

Julien Fleurence, Sophie Fougeray, Meriem Bahri, Denis Cochonneau, Béatrice Clémenceau, François Paris, Andras Heczey, Stéphane Birklé. Targeting-Acetyl-GD2 Ganglioside for Cancer Immunotherapy. Journal of Immunology Research. (2017) [Epub ahead of print]. inserm-01474322

Judith Raimbourg, Marie-Pierre Joalland, Mathilde Cabart, Ludmilla dePlater, Fanny Bouquet, Ariel Savina, Didier Decaudin, Jaafar Bennouna,François Vallette, Lisenn Lalier. Sensitization of EGFR wild-type non-small cell lung cancer cells to EGFR-tyrosine kinase inhibitor erlotinib.. Molecular Cancer Therapeutics. (2017) 1634-1644. inserm-01525974

Hannah Brown, Kristina Schiavone, François Gouin, Marie-Françoise Heymann, Dominique Heymann. Biology of bone sarcomas and new therapeutic developments. Calcified Tissue International. (2017) inserm-01653600

Elizabeth Harford-Wright, Gwennan André-Grégoire, Kathryn Jacobs, Lucas Treps, Sophie Le Gonidec, Héloïse Leclair, Sara Gonzalez-Diest, Quentin Roux, François Guillonneau, Delphine Loussouarn, Lisa Oliver, François Vallette, Fabienne Foufelle, Philippe Valet, Anthony Davenport, Robert Glen, Nicolas Bidère, Julie Gavard. Pharmacological targeting of apelin impairs glioblastoma growth. Brain – A Journal of Neurology. (2017) Epub ahead of print. inserm-01611131

Cristina Bagacean, Adrian Tempescul, Christelle Le Dantec, Anne Bordron, Audrey Mohr, Hussam Saad, Valerie Olivier, Mihnea Zdrenghea, Victor Cristea, Pierre-François Cartron, Nathalie Douet-Guilbert, Christian Berthou, Yves Renaudineau. Alterations in DNA methylation/demethylation intermediates predict clinical outcome in chronic lymphocytic leukemia. Oncotarget. (2017) hal-01573947

EQUIPE 10

Steven Le Gouill, René-Olivier Casasnovas. Interim PET-driven strategy in de novo diffuse large B-cell lymphoma: do we trust the driver ?. Blood. (2017) 3059-3070. inserm-01556383

Shaji Kumar, Jonathan Kaufman, Cristina Gasparetto, Joseph Mikhael, Ravi Vij, Brigitte Pegourie, Lofti Benboubker, Thierry Facon, Martine Amiot, Philippe Moreau, Elizabeth Punnoose, Stefanie Alzate, Martin Dunbar, Tu Xu, Suresh K. Agarwal, Sari Heitner Enschede, Joel D. Leverson, Jeremy A. Ross, Paulo C. Maciag, Maria Verdugo, Cyrille Touzeau. Efficacy of venetoclax as targeted therapy for relapsed/refractory t(11;14) multiple myeloma. Blood. (2017) 2401-2409. inserm-01631468

Laurence Lodé, Audrey Ménard, Laurent Flet, Steven Richebourg, Marion Loirat, Marion Eveillard, Yannick Le Bris, Catherine Godon, Olivier Theisen, Anne-Laure Gagez, Guillaume Cartron, Thérèse Commes-Maerten, Bruno Villemagne, Odile Luycx, Pascal Godmer, Catherine Pellat-Deceunynck, Thierry Soussi, Marie Béné, Jacques Delaunay, Pierre Peterlin. Emergence and evolution of TP53 mutations are a key feature of disease progression in myelodysplastic patients with lower-risk del(5q) treated with lenalidomide.. Haematologica. (2017) Epub ahead of print. inserm-01691580

Joel Leverson, Deepak Sampath, Andrew Souers, Saul Rosenberg, Wayne Fairbrother, Martine Amiot, Marina Konopleva, Anthony Letai. Found in Translation: How Preclinical Research Is Guiding the Clinical Development of the BCL2-Selective Inhibitor Venetoclax. Cancer Discovery / Cancer Discov. (2017) Epub ahead of print. inserm-01638832

Jeroen Guikema, Martine Amiot, Eric Eldering. Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer. Expert Opinion on Therapeutic Targets. (2017) 767-779. inserm-01558188

Hanna Karvonen, David Chiron, Wilhelmiina Niininen, Sara Ek, Mats Jerkeman, Elaheh Moradi, Matti Nykter, Caroline Heckman, Olli Kallioniemi, Astrid Murumägi, Daniela Ungureanu. Crosstalk between ROR1 and BCR pathways defines novel treatment strategies in mantle cell lymphoma. Blood. (2017) 2257-2268. inserm-01654519

Clément Bailly, Rodolphe Leforestier, Bastien Jamet, Thomas Carlier, Mickael Bourgeois, François Guérard, Cyrille Touzeau, Philippe Moreau, Michel Chérel, Françoise Kraeber-Bodéré, Caroline Bodet-Milin. PET Imaging for Initial Staging and Therapy Assessment in Multiple Myeloma Patients. International Journal of Molecular Sciences. (2017) pii: E445. inserm-01500327

Benoit Tessoulin, Marion Eveillard, Anne Lok, David Chiron, Philippe Moreau, Martine Amiot, Agnès Moreau-Aubry, Steven Le Gouill, Catherine Pellat-Deceunynck. p53 dysregulation in B-cell malignancies: More than a single gene in the pathway to hell. Blood Reviews. (2017) [Epub ahead of print]. inserm-01493742

Antonin Papin, Steven Le Gouill, David Chiron. Rationale for targeting tumor cells in their microenvironment for mantle cell lymphoma treatment. Leukemia & lymphoma. (2017) Epub ahead of print. inserm-01655227

Aline Clavert, Zinaida Peric, Eolia Brissot, Florent Malard, Thierry Guillaume, Jacques Delaunay, Viviane Dubruille, Steven Le Gouill, Beatrice Mahe, Thomas Gastinne, Nicolas Blin, Jean-Luc Harousseau, Philippe Moreau, Noel Milpied, Mohamad Mohty, Patrice Chevallier. Late Complications and Quality of Life after Reduced-Intensity Conditioning Allogeneic Stem Cell Transplantation.. Biology of Blood and Marrow Transplantation. (2017) 140-146. hal-01568571

Ali Younes, Gilles Montavon, Sebastien G. Gouin, Emy Andre-Joyaux, Roxane Peumery, Thibaut Chalopin, Cyrille Alliot, Marcel Mokili, Julie Champion, David Deniaud. Investigation of a new `’ N2S2O2 `’ chelating agent with high Po(IV) affinity. Chemical Communications. (2017) 6492-6495. hal-02141226

Ali Younes, Cyrille Alliot, Marcel Mokili, Gilles Montavon. Is Polonium-210 a Good Indicator for Anthropogenic Radioactivity?. DOI 10.1089/cbr.2018.2496. (2017) 356-360. hal-02004388

EQUIPE 11

Salomon Manier, Chia-Jen Liu, Hervé Avet-Loiseau, Jihye Park, Jiantao Shi, Federico Campigotto, Karma Salem, Daisy Huynh, Siobhan Glavey, Bradley Rivotto, Antonio Sacco, Aldo Roccaro, Juliette Bouyssou, Stéphane Minvielle, Philippe Moreau, Thierry Facon, Xavier Leleu, Edie Weller, Lorenzo Trippa, Irene Ghobrial. Prognostic role of circulating exosomal miRNAs in multiple myeloma. Blood. (2017) 2429 – 2436. inserm-01611113

Niccolò Bolli, Giulia Biancon, Matahi Moarii, Silvia Gimondi, Yilong Li, Chiara De Philippis, Francesco Maura, Vijitha Sathiaseelan, Yu-Tzu Tai, Laura Mudie, Sarah O’Meara, Keiran Raine, Jon Teague, Adam Butler, Cristiana Carniti, Moritz Gerstung, Tina Bagratuni, Efstathios Kastritis, Meletios Dimopoulos, Paolo Corradini, Kenneth Anderson, Philippe Moreau, Stephane Minvielle, Peter Campbell, Elli Papaemmanuil, Hervé Avet-Loiseau, Nikhil Munshi. Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups. Leukemia. (2017) Epub ahead of print. inserm-01808859

Francesco Maura, Mia Petljak, Marta Lionetti, Ingrid Cifola, Winnie Liang, Eva Pinatel, Ludmil Alexandrov, Anthony Fullam, Inigo Martincorena, Kevin Dawson, Nicos Angelopoulos, Mehmet Samur, Raphael Szalat, Jorge Zamora, Patrick Tarpey, Helen Davies, Paolo Corradini, Kenneth Anderson, Stéphane Minvielle, Antonino Neri, Herve Avet-Loiseau, Jonathan Keats, Peter Campbell, Nikhil Munshi, Niccolo Bolli. Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines. Leukemia. (2017) 1044-1048. inserm-01808879

Bertrand Miannay, Stéphane Minvielle, Olivier Roux, Pierre Drouin, Hervé Avet-Loiseau, Catherine Guérin-Charbonnel, Wilfried Gouraud, Michel Attal, Thierry Facon, Nikhil Munshi, Philippe Moreau, Loïc Campion, Florence Magrangeas, Carito Guziolowski. Logic programming reveals alteration of key transcription factors in multiple myeloma. Scientific Reports. (2017) 9257. inserm-01611119

EQUIPE 12

EQUIPE 13

Valentina Kalichuk, Axelle Renodon-Cornière, Ghislaine Béhar, Federico Carrión, Gonzalo Obal, Mike Maillasson, Barbara Mouratou, Véronique Préat, Frédéric Pecorari. A novel, smaller scaffold for Affitins: Showcase with binders specific for EpCAM.. Biotechnology and Bioengineering. (2017) Epub ahead of print. inserm-01629637

Mickael Bourgeois, Clément Bailly, Mathieu Frindel, François Guérard, Michel Chérel, Alain Faivre-Chauvet, Françoise Kraeber-Bodéré, Caroline Bodet-Milin. Radioimmunoconjugates for treating cancer: recent advances and current opportunities. Expert Opinion on Biological Therapy. (2017) 813 – 819. inserm-01635514

Glenn Flux, K. Sjogreen Gleisner, C. Chiesa, M. Lassmann, Nicolas Chouin, J. Gear, M. Bardiès, S. Walrand, K. Bacher, U. Eberlein, M. Ljungberg, L. Strigari, E. Visser, M. W. Konijnenberg. From fixed activities to personalized treatments in radionuclide therapy: lost in translation?. European Journal of Nuclear Medicine and Molecular Imaging. (2017) Epub ahead of print. inserm-01635732

François Guérard, Maryline Beyler, Y.-S Lee, Raphaël Tripier, Jean-François Gestin, Martin Brechbiel. Investigation of the complexation of nat Zr(IV) and 89 Zr(IV) by hydroxypyridinones for the develop- ment of chelators for PET imaging applications †.Dalton Transactions. (2017) 4749-4758. inserm-01496515

François Guérard, Laurent Navarro, Y.-S. Lee, Aurélia Roumesy, Cyrille Alliot, Michel Chérel, M.W. Brechbiel, Jean-François Gestin. Bifunctional aryliodonium salts for highly efficient radioiodination and astatination of antibodies. Bioorganic and Medicinal Chemistry. (2017) Epub ahead of print. inserm-01592684

Fijs van Leeuwen, Bart Cornelissen, Federico Caobelli, Laura Evangelista, Latifa Rbah-Vidal, Silvana Vecchio, Catarina Xavier, Jacques Barbet, Marion de Jong. Generation of fluorescently labeled tracers – which features influence the translational potential?. European Association of Nuclear Medicine, issuing body – EJNMMI radiopharmacy and chemistry. (2017) 15. inserm-01782195

F. Guérard. L’astate-211 pour la radiothérapie vectorisée des cancers. L’Actualité Chimique. (2017) 143-144. inserm-01628339

Eric Aboagye, Françoise Kraeber-Bodéré. Highlights lecture EANM 2016: “Embracing molecular imaging and multi-modal imaging: a smart move for nuclear medicine towards personalized medicine”.European Journal of Nuclear Medicine and Molecular Imaging. (2017) 1559 – 1574. inserm-01635423

Delphine Séhédic, Igor Chourpa, Clément Tétaud, Audrey Griveau, Claire Loussouarn, Sylvie Avril, Claire Legendre, Nicolas Lepareur, Didier Wion, François Hindré, François Davodeau, Emmanuel Garcion. Locoregional Confinement and Major Clinical Benefit of 188 Re-Loaded CXCR4-Targeted Nanocarriers in an Orthotopic Human to Mouse Model of Glioblastoma. Theranostics. (2017) 4517 – 4536. inserm-01631431

David Sarrut, Adrien Halty, Jean-Noël Badel, Ludovic Ferrer, Manuel Bardiès. Voxel-based multi-model fitting method for modelling time activity curves in SPECT images. Medical Physics. (2017) 6280-6288. hal-01611266

Bastien Jamet, Thomas Carlier, Loïc Campion, Emmanuelle Bompas, Sylvie Girault, Fanny Borrely, Ludovic Ferrer, Maxime Rousseau, Yann Venel, Françoise Kraeber-Bodéré, Caroline Rousseau. Initial FDG-PET/CT predicts survival in adults Ewing sarcoma family of tumors. Oncotarget. (2017) 77050-77060. inserm-01636020

EQUIPE 14

Vincent Pautu, Daniela Leonetti, Elise Lepeltier, Nicolas Clere, Catherine Passirani. Nanomedicine as a potent strategy in melanoma tumor microenvironment. Pharmacological Research. (2017) 31 – 53. inserm-01814682

Perrine Paul-Gilloteaux, Vincent Potiron, Grégory Delpon, Stéphane Supiot, Sophie Chiavassa, François Paris, Sylvain Costes. Optimizing radiotherapy protocols using computer automata to model tumour cell death as a function of oxygen diffusion processes. Scientific Reports. (2017) 2280. inserm-01550008

Julien Fleurence, Sophie Fougeray, Meriem Bahri, Denis Cochonneau, Béatrice Clémenceau, François Paris, Andras Heczey, Stéphane Birklé. Targeting-Acetyl-GD2 Ganglioside for Cancer Immunotherapy. Journal of Immunology Research. (2017) [Epub ahead of print]. inserm-01474322

Isabelle Corre, François Paris, Jacques Huot. The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells. Oncotarget. (2017) Epub ahead of print. inserm-01550120

Alan Dal Pra, Thomas Zilli, Stéphane Supiot. Editorial: Controversies and Perspectives in the Use of Postoperative radiotherapy for Prostate Cancer. Frontiers in Oncology. (2017) 275. inserm-01819092

EQUIPE 15

Lucas Treps, Raul Perret, Sébastien Edmond, Damien Ricard, Julie Gavard. Glioblastoma stem-like cells secrete the pro-angiogenic VEGF-A factor in extracellular vesicles. Journal of Extracellular Vesicles. (2017) 1359479. inserm-01573268

Lucas Treps, Julie Gavard. Assaying the Action of Secreted Semaphorins on Vascular Permeability. Methods in Molecular Biology. (2017). inserm-01662346

EQUIPE 16

Cédric Cleyrat, Romain Girard, Eun Choi, Eric Jeziorski, Thierry Lavabre-Bertrand, Sylvie Hermouet, Serge Carillo, Bridget Wilson. Gene editing rescue of a novel MPL mutant associated with congenital amegakaryocytic thrombocytopenia. Blood Advances. (2017) 1815-1826. inserm-01595962

Adrien Bosseboeuf, Sophie Allain-Maillet, Nicolas Mennesson, Anne Tallet, Cédric Rossi, Laurent Garderet, Denis Caillot, Philippe Moreau, Eric Piver, François Girodon, Hélène Perreault, Sophie Brouard, Arnaud Nicot, Edith Bigot-Corbel, Sylvie Hermouet, Jean Harb. Pro-inflammatory State in Monoclonal Gammopathy of Undetermined Significance and in Multiple Myeloma Is Characterized by Low Sialylation of Pathogen-Specific and Other Monoclonal Immunoglobulins.. Frontiers in Immunology. (2017) 1347. inserm-01628293

Adrien Bosseboeuf, Delphine Féron, Anne Tallet, Cédric Rossi, Cathy Charlier, Laurent Garderet, Denis Caillot, Philippe Moreau, Marina Cardó-Vila, Renata Pasqualini, Wadih Arap, Alfreda Nelson, Bridget Wilson, Hélène Perreault, Eric Piver, Pierre Weigel, François Girodon, Jean Harb, Edith Bigot-Corbel, Sylvie Hermouet. Monoclonal IgG in MGUS and multiple myeloma targets infectious pathogens. JCI Insight. (2017) Epub ahead of print. inserm-01628286

EQUIPE 17

Thomas Briot, Emilie Roger, Nolwenn Lautram, Alexis Verger, Anne Clavreul, Frédéric Lagarce. Development and in vitro evaluations of new decitabine nanocarriers for the treatment of acute myeloid leukemia. International Journal of Nanomedicine. (2017) 8427 – 8442. inserm-01668530
Rahmet Parilti, David Alaimo, Bruno Grignard, Franck Boury, Steven Howdle, Christine Jerome. Mild synthesis of poly(HEMA)-networks as well-defined nanoparticles in supercritical carbon dioxide. Journal of materials chemistry‎ B. (2017) 5806 – 5815. inserm-01631383

Nina Henry, Johann Clouet, Catherine Le Visage, Pierre Weiss, Eric Gautron, Denis Renard, Thomas Cordonnier, Franck Boury, Bernard Humbert, Hélène Terrisse, Jérôme Guicheux, Jean Le Bideau. Silica nanofibers as a new drug delivery system: a study of the protein–silica interactions. Journal of materials chemistry‎ B. (2017) 2908 – 2920. inserm-01631453

José Hureaux, Franck Lacœuille, Frédéric Lagarce, Marie-Christine Rousselet, Aurélien Contini, Patrick Saulnier, Jean-Pierre Benoît, Thierry Urban. Absence of lung fibrosis after a single pulmonary delivery of lipid nanocapsules in rats. International Journal of Nanomedicine. (2017) 8159 – 8170. inserm-01813483

Felana Andriatsitoaina, Nora Collomb, Alexis Arnaud, Florence Forbes, Jean-Paul Issartel, Claire Loussouarn, Emmanuel Garcion, Emmanuel Luc Barbier, Benjamin Lemasson. Suivi de l’hétérogénéité de la croissance de 4 modèles de gliomes par IRM multiparamétrique analysée par clustering. [Congrès]. (2017). hal-01652029

Bathabile Ramalapa, Oscar Crasson, Marylène Vandevenne, Alain Gibaud, Emmanuel Garcion, Thomas Cordonnier, Moreno Galleni, Frank Boury. Protein–polysaccharide complexes for enhanced protein delivery in hyaluronic acid templated calcium carbonate microparticles. Journal of materials chemistry‎ B. (2017) 7360 – 7368. inserm-01631419

Anne Clavreul, Milad Pourbaghi-Masouleh, Emilie Roger, Nolwenn Lautram, Claudia Montero-Menei, Philippe Menei. Human mesenchymal stromal cells as cellular drug-delivery vectors for glioblastoma therapy: a good deal?. Journal of Experimental and Clinical Cancer Research. (2017) 135. inserm-01631360

A. Roux, F. Caire, J. Guyotat, Philippe Menei, P. Metellus, J. Pallud, Neuro-Oncology Club French Neurosurgical Society. Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery. Neurochirurgie. (2017) 433 – 443. inserm-01814217

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